Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL135C
Length:
114
Number of sequences:
5887
Description:
YNL135C FPR1 SGDID:S000005079, Chr XIV from 372226-371882, Genome Release 64-1-1, reverse complement, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P20081    114   FKBP_YEAST FK506-binding protein 1 OS=Sacchar...1142e-77     230     100     100GO:0016020; C:membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005528; F:FK506 binding; IBA:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006325; P:chromatin organization; IGI:SGD.::GO:0009092; P:homoserine metabolic process; IGI:SGD.::GO:0006457; P:protein folding; IMP:SGD.
2Q754K8    114   FKBP_ASHGO FK506-binding protein 1 OS=Y-1056)...1145e-73     219     93     96GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:RefGenome.
GO:0005528; F:FK506 binding; ISS:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; ISS:RefGenome.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
3Q6FMA3    114   FKBP_CANGA FK506-binding protein 1 OS=NRRL Y-...1145e-73     219     93     96GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
4Q6CX30    114   FKBP_KLULA FK506-binding protein 1 OS=1267 / ...1144e-70     212     89     93GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
5Q6BX45    112   FKBP_DEBHA FK506-binding protein 1 OS=0083 / ...1087e-53     167     74     83GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
6O42993    112   FKBP_SCHPO FK506-binding protein OS=Schizosac...1016e-50     160     74     86GO:0005829; C:cytosol; IDA:PomBase.::GO:0016020; C:membrane; ISS:RefGenome.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005528; F:FK506 binding; ISS:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0006457; P:protein folding; NAS:PomBase.
7Q6CF41    108   FKBP_YARLI FK506-binding protein 1 OS=lipolyt...1061e-49     159     71     82GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
8O94746    108   FKBP_CRYNV FK506-binding protein 1 OS=grubii)...1062e-44     146     68     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
9P0CP94    108   FKBP_CRYNJ FK506-binding protein 1 OS=ATCC MY...1063e-44     145     66     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
10P0CP95    108   FKBP_CRYNB FK506-binding protein 1 OS=(Filoba...1063e-44     145     66     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
11Q6KBA8    108   FKB1A_EMENI FK506-binding protein 1A OS=194 /...1061e-42     141     66     77GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:RefGenome.
GO:0005528; F:FK506 binding; ISS:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; ISS:RefGenome.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
12P0C1J3    108   FKBP1_RHIO9 FK506-binding protein 1 OS=43880)...1062e-42     141     64     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
13P48375    108   FKB12_DROME 12 kDa FK506-binding protein OS=D...1068e-42     139     62     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IBA:RefGenome.
GO:0005528; F:FK506 binding; IBA:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
14Q4WLV6    112   FKB1A_ASPFU FK506-binding protein 1A OS=A1100...1009e-42     139     67     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
15P18203    108   FKB1A_BOVIN Peptidyl-prolyl cis-trans isomera...1062e-40     135     58     77GO:0030424; C:axon; ISS:RefGenome.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:RefGenome.
GO:0005528; F:FK506 binding; ISS:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.
GO:0032513; P:negative regulation of protein phosphatase type 2B activity; ISS:RefGenome.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; ISS:RefGenome.::GO:0042110; P:T cell activation; NAS:BHF-UCL.
16P26883    108   FKB1A_MOUSE Peptidyl-prolyl cis-trans isomera...1063e-40     135     57     76GO:0030424; C:axon; IBA:RefGenome.::GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:MGI.
GO:0005528; F:FK506 binding; IDA:MGI.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.
GO:0019221; P:cytokine-mediated signaling pathway; IMP:MGI.::GO:0060347; P:heart trabecula formation; IMP:BHF-UCL.::GO:0006936; P:muscle contraction; IMP:MGI.::GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IMP:BHF-UCL.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:MGI.::GO:0031000; P:response to caffeine; IMP:MGI.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
17P62943    108   FKB1A_RABIT Peptidyl-prolyl cis-trans isomera...1064e-40     135     58     77GO:0005792; C:microsome; IDA:AgBase.::GO:0014802; C:terminal cisterna; IDA:BHF-UCL.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
18P62942    108   FKB1A_HUMAN Peptidyl-prolyl cis-trans isomera...1064e-40     135     58     77GO:0030424; C:axon; IBA:RefGenome.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0033017; C:sarcoplasmic reticulum membrane; IBA:RefGenome.::GO:0014802; C:terminal cisterna; ISS:BHF-UCL.
GO:0048185; F:activin binding; IPI:BHF-UCL.::GO:0005528; F:FK506 binding; IDA:BHF-UCL.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0046332; F:SMAD binding; IPI:BHF-UCL.::GO:0034713; F:type I transforming growth factor beta receptor binding; ISS:BHF-UCL.
GO:0006458; P:'de novo' protein folding; TAS:BHF-UCL.::GO:0034205; P:beta-amyloid formation; IDA:BHF-UCL.::GO:0043206; P:fibril organization; IDA:BHF-UCL.::GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.::GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IDA:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.::GO:0042026; P:protein refolding; TAS:BHF-UCL.::GO:0032925; P:regulation of activin receptor signaling pathway; IDA:BHF-UCL.::GO:0050776; P:regulation of immune response; IMP:BHF-UCL.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.::GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.::GO:0042110; P:T cell activation; NAS:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
19Q62658    108   FKB1A_RAT Peptidyl-prolyl cis-trans isomerase...1061e-38     131     56     75GO:0043679; C:axon terminus; IDA:RGD.::GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005792; C:microsome; IDA:RGD.::GO:0033017; C:sarcoplasmic reticulum membrane; IBA:RefGenome.
GO:0005528; F:FK506 binding; IDA:RGD.::GO:0030544; F:Hsp70 protein binding; IPI:RGD.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.::GO:0034713; F:type I transforming growth factor beta receptor binding; IDA:BHF-UCL.
GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IBA:RefGenome.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IBA:RefGenome.::GO:0010039; P:response to iron ion; IEP:RGD.
20O42123    108   FKB1A_XENLA Peptidyl-prolyl cis-trans isomera...1061e-38     131     56     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
21Q9Z2I2    108   FKB1B_MOUSE Peptidyl-prolyl cis-trans isomera...1063e-37     127     56     75GO:0034704; C:calcium channel complex; IBA:RefGenome.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:MGI.
GO:0005528; F:FK506 binding; IDA:MGI.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:MGI.
GO:0030073; P:insulin secretion; IMP:MGI.::GO:0010459; P:negative regulation of heart rate; IMP:BHF-UCL.::GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IBA:RefGenome.::GO:0019227; P:neuronal action potential propagation; IMP:MGI.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IMP:BHF-UCL.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IMP:BHF-UCL.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IMP:MGI.::GO:0009749; P:response to glucose stimulus; IMP:MGI.::GO:0006939; P:smooth muscle contraction; IMP:MGI.::GO:0042098; P:T cell proliferation; IMP:MGI.
22P97534    108   FKB1B_RAT Peptidyl-prolyl cis-trans isomerase...1064e-37     127     56     75GO:0034704; C:calcium channel complex; IBA:RefGenome.::GO:0005792; C:microsome; IDA:RGD.::GO:0033017; C:sarcoplasmic reticulum membrane; IBA:RefGenome.
GO:0030551; F:cyclic nucleotide binding; IDA:RGD.::GO:0005528; F:FK506 binding; IDA:RGD.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IBA:RefGenome.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IBA:RefGenome.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0010033; P:response to organic substance; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.
23P68106    108   FKB1B_HUMAN Peptidyl-prolyl cis-trans isomera...1069e-37     126     56     74GO:0034704; C:calcium channel complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IC:BHF-UCL.::GO:0033017; C:sarcoplasmic reticulum membrane; IBA:RefGenome.
GO:0005528; F:FK506 binding; IDA:BHF-UCL.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.::GO:0005102; F:receptor binding; IPI:BHF-UCL.
GO:0006458; P:'de novo' protein folding; TAS:BHF-UCL.::GO:0010459; P:negative regulation of heart rate; ISS:BHF-UCL.::GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IDA:BHF-UCL.::GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.::GO:0042026; P:protein refolding; TAS:BHF-UCL.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IMP:BHF-UCL.::GO:0051775; P:response to redox state; IDA:BHF-UCL.
24P68107    108   FKB1B_BOVIN Peptidyl-prolyl cis-trans isomera...1069e-37     126     56     74GO:0034704; C:calcium channel complex; ISS:RefGenome.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:RefGenome.
GO:0005528; F:FK506 binding; ISS:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; ISS:RefGenome.
GO:0032513; P:negative regulation of protein phosphatase type 2B activity; ISS:RefGenome.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; ISS:RefGenome.
25P28870    124   FKBP_CANAL FK506-binding protein 1 OS=Candida...1164e-36     125     57     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008144; F:drug binding; IPI:CGD.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IGI:CGD.
GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.
26Q8HYX6    108   FKB1B_RABIT Peptidyl-prolyl cis-trans isomera...1061e-35     123     55     73GO:0005792; C:microsome; IDA:AgBase.::GO:0016529; C:sarcoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
27Q54SR7    133   FKBP2_DICDI FK506-binding protein 2 OS=Dictyo...1022e-31     113     56     69GO:0016020; C:membrane; IBA:RefGenome.
GO:0005528; F:FK506 binding; IBA:RefGenome.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
28Q38931    551   FKB62_ARATH Peptidyl-prolyl cis-trans isomera...1110.0005     41.6     26     45GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0070370; P:cellular heat acclimation; IMP:UniProtKB.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
29P0CP96    141   FKBP2_CRYNJ FK506-binding protein 2 OS=ATCC M...1001e-30     112     53     70GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
30P0CP97    141   FKBP2_CRYNB FK506-binding protein 2 OS=(Filob...1001e-30     112     53     70GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
31P56989    109   FKBP_NEIMA FK506-binding protein OS=Neisseria...1071e-30     110     53     67
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
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