| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53916 | 434 | TEP1_YEAST Probable phosphatidylinositol 3,4,... | 434 | 0 | 899 | 100 | 100 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:SGD. | 2 | P60484 | 403 | PTEN_HUMAN Phosphatidylinositol 3,4,5-trispho... | 234 | 2e-17 | 87 | 27 | 47 | GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; ISS:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; ISS:BHF-UCL.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.::GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.::GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.::GO:0031658; P:negative regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.::GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; TAS:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; ISS:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 3 | P60483 | 403 | PTEN_CANFA Phosphatidylinositol 3,4,5-trispho... | 234 | 2e-17 | 87 | 27 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 4 | O08586 | 403 | PTEN_MOUSE Phosphatidylinositol 3,4,5-trispho... | 234 | 3e-17 | 87 | 27 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:BHF-UCL.::GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048738; P:cardiac muscle tissue development; IMP:MGI.::GO:0032286; P:central nervous system myelin maintenance; IMP:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0021542; P:dentate gyrus development; IMP:BHF-UCL.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048853; P:forebrain morphogenesis; IMP:BHF-UCL.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0007611; P:learning or memory; IMP:BHF-UCL.::GO:0045475; P:locomotor rhythm; IMP:BHF-UCL.::GO:0060291; P:long-term synaptic potentiation; IMP:BHF-UCL.::GO:0060179; P:male mating behavior; IMP:BHF-UCL.::GO:0042711; P:maternal behavior; IMP:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:BHF-UCL.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0031642; P:negative regulation of myelination; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0090071; P:negative regulation of ribosome biogenesis; IMP:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; IMP:BHF-UCL.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IMP:BHF-UCL.::GO:0060134; P:prepulse inhibition; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IMP:BHF-UCL.::GO:0060736; P:prostate gland growth; IMP:MGI.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:MGI.::GO:0033032; P:regulation of myeloid cell apoptotic process; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0060074; P:synapse maturation; IMP:BHF-UCL. | 5 | Q54JL7 | 639 | CNRN_DICDI Phosphatidylinositol 3,4,5-trispho... | 227 | 4e-17 | 87 | 30 | 43 | | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0030835; P:negative regulation of actin filament depolymerization; IMP:dictyBase.::GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:dictyBase.::GO:0014066; P:regulation of phosphatidylinositol 3-kinase cascade; IMP:dictyBase. | 6 | Q9PUT6 | 402 | PTEN_XENLA Phosphatidylinositol 3,4,5-trispho... | 233 | 9e-16 | 82.4 | 26 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB. | 7 | Q8T9S7 | 533 | PTEN_DICDI Phosphatidylinositol 3,4,5-trispho... | 227 | 0.0000000000004 | 74.7 | 25 | 44 | GO:0051285; C:cell cortex of cell tip; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031254; C:trailing edge; IDA:dictyBase. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; TAS:dictyBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007015; P:actin filament organization; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; TAS:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IDA:dictyBase.::GO:0050919; P:negative chemotaxis; IMP:dictyBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0045761; P:regulation of adenylate cyclase activity; IGI:dictyBase.::GO:0022604; P:regulation of cell morphogenesis; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 8 | O94526 | 348 | PTEN_SCHPO Phosphatidylinositol 3,4,5-trispho... | 143 | 0.000000002 | 62.8 | 29 | 50 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0009992; P:cellular water homeostasis; IMP:PomBase.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.::GO:0007033; P:vacuole organization; IMP:PomBase. | 9 | Q4R6N0 | 566 | TPTE2_MACFA Phosphatidylinositol 3,4,5-trisph... | 232 | 0.00001 | 51.2 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 10 | Q6XPS3 | 522 | TPTE2_HUMAN Phosphatidylinositol 3,4,5-trisph... | 230 | 0.00002 | 50.4 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 11 | Q68CZ2 | 1445 | TENS3_HUMAN Tensin-3 OS=Homo sapiens (Human).... | 92 | 0.00003 | 50.4 | 28 | 51 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 12 | Q5SSZ5 | 1440 | TENS3_MOUSE Tensin-3 OS=Mus musculus (Mouse).... | 92 | 0.00005 | 49.7 | 28 | 50 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI. | 13 | Q04205 | 1744 | TENS_CHICK Tensin OS=Gallus gallus (Chicken).... | 208 | 0.0001 | 48.5 | 24 | 38 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | P56180 | 551 | TPTE_HUMAN Putative tyrosine-protein phosphat... | 214 | 0.0001 | 48.1 | 22 | 41 | GO:0016021; C:integral to membrane; TAS:ProtInc. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; TAS:ProtInc. | 15 | Q63HR2 | 1409 | TENC1_HUMAN Tensin-like C1 domain-containing ... | 95 | 0.0001 | 48.1 | 32 | 45 | GO:0005925; C:focal adhesion; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB. | 16 | Q8CGB6 | 1400 | TENC1_MOUSE Tensin-like C1 domain-containing ... | 95 | 0.0002 | 47.8 | 32 | 45 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IMP:MGI.::GO:0032963; P:collagen metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001822; P:kidney development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0048871; P:multicellular organismal homeostasis; IMP:MGI.::GO:0014850; P:response to muscle activity; IMP:MGI. | 17 | Q9HBL0 | 1735 | TENS1_HUMAN Tensin-1 OS=Homo sapiens (Human).... | 208 | 0.0004 | 46.6 | 23 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q9GLM4 | 1715 | TENS1_BOVIN Tensin-1 OS=Bos taurus (Bovine). ... | 208 | 0.001 | 45.1 | 23 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | P38148 | 807 | PPS1_YEAST Dual specificity protein phosphata... | 63 | 0.006 | 42.7 | 35 | 57 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IGI:SGD. | 20 | Q54R42 | 230 | DUSP2_DICDI Probable dual specificity protein... | 68 | 0.007 | 41.6 | 34 | 51 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 21 | Q9LVN1 | 1266 | FH13_ARATH Formin-like protein 13 OS=Arabidop... | 89 | 0.052 | 39.7 | 30 | 52 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 22 | Q9BY84 | 665 | DUS16_HUMAN Dual specificity protein phosphat... | 71 | 0.1 | 38.5 | 35 | 49 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0045204; P:MAPK export from nucleus; TAS:UniProtKB.::GO:0045209; P:MAPK phosphatase export from nucleus, leptomycin B sensitive; TAS:UniProtKB. | 23 | Q39491 | 276 | PTP3_CHLMO Dual specificity protein phosphata... | 51 | 0.13 | 37.7 | 37 | 51 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 24 | Q6ZCX3 | 1364 | FH6_ORYSJ Formin-like protein 6 OS=Oryza sati... | 86 | 0.14 | 38.5 | 30 | 51 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 25 | P0C597 | 214 | DUPD1_CHICK Dual specificity phosphatase DUPD... | 35 | 0.28 | 36.6 | 49 | 66 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 26 | Q8WTR2 | 217 | DUS19_HUMAN Dual specificity protein phosphat... | 68 | 0.29 | 36.6 | 29 | 44 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0008579; F:JUN kinase phosphatase activity; IBA:RefGenome.::GO:0005078; F:MAP-kinase scaffold activity; ISS:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; ISS:BHF-UCL.::GO:0030295; F:protein kinase activator activity; ISS:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:BHF-UCL. | 27 | P24656 | 168 | PTP_NPVAC Tyrosine-protein phosphatase OS=Aut... | 63 | 0.4 | 35.4 | 29 | 48 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 28 | Q38806 | 195 | HSP22_ARATH 22.0 kDa heat shock protein OS=Ar... | 52 | 0.46 | 35.8 | 37 | 52 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0009408; P:response to heat; IEP:UniProtKB. | 29 | Q7XWS7 | 1669 | FH12_ORYSJ Formin-like protein 12 OS=Oryza sa... | 199 | 0.49 | 36.6 | 25 | 40 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 30 | Q9D9D8 | 189 | DUS21_MOUSE Dual specificity phosphatase 21 O... | 102 | 0.66 | 35 | 30 | 45 | GO:0019898; C:extrinsic to membrane; ISS:MGI.::GO:0005743; C:mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI. | 31 | O14976 | 1311 | GAK_HUMAN Cyclin-G-associated kinase OS=Homo ... | 207 | 0.83 | 35.8 | 23 | 35 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. |
