Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL128W
Length:
434
Number of sequences:
5887
Description:
YNL128W TEP1 SGDID:S000005072, Chr XIV from 382359-383663, Genome Release 64-1-1, Verified ORF, "Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O14976    1311   GAK_HUMAN Cyclin-G-associated kinase OS=Homo ...2070.83     35.8     23     35GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
32Q5PEA9    543   SPTP_SALPA Secreted effector protein sptP OS=...601.2     35.4     32     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
33P74851    543   SPTP_SALTI Secreted effector protein sptP OS=...601.2     35     32     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
34P74873    543   SPTP_SALTY Secreted effector protein sptP OS=...601.2     35     32     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
35P97874    1305   GAK_RAT Cyclin-G-associated kinase OS=Rattus ...2071.2     35.4     22     35GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
36P0C593    212   DUPD1_MONDO Dual specificity phosphatase DUPD...501.3     34.3     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
37Q9ZQP1    337   DSP8_ARATH Putative dual specificity protein ...491.3     34.7     33     55
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
38P34137    522   PTP1_DICDI Tyrosine-protein phosphatase 1 OS=...581.3     35     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
39Q6AXW7    204   DUS18_RAT Dual specificity protein phosphatas...1021.4     34.3     31     46GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
40Q17QJ3    211   DUS26_BOVIN Dual specificity protein phosphat...611.5     34.3     36     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
41Q9P7H1    537   FLP1_SCHPO Tyrosine-protein phosphatase CDC14...851.9     34.7     27     48GO:0000777; C:condensed chromosome kinetochore; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IGI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IGI:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0035853; P:chromosome passenger complex localization to spindle midzone; IMP:PomBase.::GO:0031566; P:contractile ring maintenance involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031565; P:cytokinesis checkpoint; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IGI:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; TAS:PomBase.::GO:0007096; P:regulation of exit from mitosis; IMP:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0031134; P:sister chromatid biorientation; IMP:PomBase.
42Q99956    384   DUS9_HUMAN Dual specificity protein phosphata...571.9     34.3     35     53GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005783; C:endoplasmic reticulum; IDA:HPA.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; TAS:ProtInc.
43Q8TE77    659   SSH3_HUMAN Protein phosphatase Slingshot homo...641.9     34.7     33     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
44Q6PFY9    485   CC14B_MOUSE Dual specificity protein phosphat...552.5     34.3     35     55GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.
45P43078    597   PTPX_CANAW Probable tyrosine-protein phosphat...592.8     33.9     29     49
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
46Q9VVW5    411   DUSK3_DROME Dual specificity protein phosphat...582.9     33.9     33     48GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0042127; P:regulation of cell proliferation; IGI:FlyBase.
47Q5RD73    185   DUS3_PONAB Dual specificity protein phosphata...583.7     32.7     36     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
48P51452    185   DUS3_HUMAN Dual specificity protein phosphata...583.7     32.7     36     47GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
49Q9BV47    211   DUS26_HUMAN Dual specificity protein phosphat...613.8     33.1     34     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
50Q5R6H6    211   DUS26_PONAB Dual specificity protein phosphat...613.9     32.7     34     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
51O60729    498   CC14B_HUMAN Dual specificity protein phosphat...604     33.5     30     53GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0051488; P:activation of anaphase-promoting complex activity; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.
52Q9SK28    1111   FH18_ARATH Formin-like protein 18 OS=Arabidop...864.3     33.5     28     50
GO:0003779; F:actin binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
53Q9JLY7    198   DUS14_MOUSE Dual specificity protein phosphat...394.9     32.3     49     56GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
54Q8VE01    188   DUS18_MOUSE Dual specificity protein phosphat...1155.5     32.3     25     42GO:0031314; C:extrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0031304; C:intrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.::GO:0046677; P:response to antibiotic; ISS:MGI.
55Q5FVI9    211   DUS26_RAT Dual specificity protein phosphatas...615.8     32.3     34     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
56Q9D700    211   DUS26_MOUSE Dual specificity protein phosphat...615.8     32.3     34     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
57P38590    489   MSG5_YEAST Tyrosine-protein phosphatase MSG5 ...366.3     32.7     36     61GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
58P40479    209   SDP1_YEAST Dual-specificity protein phosphata...326.6     32.3     34     63GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0033550; F:MAP kinase tyrosine phosphatase activity; IDA:SGD.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
59Q84JU4    257   IBR5_ARATH Protein-tyrosine-phosphatase IBR5 ...546.8     32.3     39     48GO:0005634; C:nucleus; IDA:TAIR.
GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.
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