Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL123W
Length:
997
Number of sequences:
5887
Description:
YNL123W NMA111 SGDID:S000005067, Chr XIV from 394685-397678, Genome Release 64-1-1, Verified ORF, "Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31E1V4H2    474   DEGPL_HALED Probable periplasmic serine endop...2970.00000000001     72     27     46GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
32P72780    394   HHOA_SYNY3 Putative serine protease HhoA OS=S...2980.00000000002     70.9     25     44GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33A4XSC0    474   DEGPL_PSEMY Probable periplasmic serine endop...1670.00000005     60.1     30     44GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
34B4JTT7    426   HTRA2_DROGR Serine protease HTRA2, mitochondr...3280.00000000002     70.9     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
35P73354    452   HTRA_SYNY3 Putative serine protease HtrA OS=S...3150.00000000002     70.9     24     43GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
36Q92743    480   HTRA1_HUMAN Serine protease HTRA1 OS=Homo sap...3280.00000000003     70.5     27     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; TAS:ProtInc.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
37Q48EU9    479   DEGPL_PSE14 Probable periplasmic serine endop...1570.17     39.3     24     43GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
38B1J4D7    479   DEGPL_PSEPW Probable periplasmic serine endop...1660.44     38.1     22     42GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
39P05676    406   Y938_SYNP6 Uncharacterized serine protease sy...3130.00000000009     68.9     25     43
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
40Q9VFJ3    422   HTRA2_DROME Serine protease HTRA2, mitochondr...3270.00000000009     68.9     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; IMP:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007005; P:mitochondrion organization; IMP:FlyBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
41B4K835    430   HTRA2_DROMO Serine protease HTRA2, mitochondr...3270.00000000009     68.9     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
42B4HEM8    422   HTRA2_DROSE Serine protease HTRA2, mitochondr...3270.0000000001     68.9     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
43B3P3J9    422   HTRA2_DROER Serine protease HTRA2, mitochondr...3270.0000000001     68.6     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
44B3LVG7    426   HTRA2_DROAN Serine protease HTRA2, mitochondr...3270.0000000001     68.6     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
45B4LY58    421   HTRA2_DROVI Serine protease HTRA2, mitochondr...3270.0000000001     68.2     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
46B4QZU6    422   HTRA2_DROSI Serine protease HTRA2, mitochondr...3270.0000000001     68.2     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
47F6AA62    479   DEGPL_PSEF1 Probable periplasmic serine endop...1570.012     43.1     23     45GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
48Q4KGQ4    476   DEGPL_PSEF5 Probable periplasmic serine endop...1630.0002     48.9     24     45GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
49F1N152    487   HTRA1_BOVIN Serine protease HTRA1 OS=Bos taur...3280.0000000003     67.8     27     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
50A5W8F5    477   DEGPL_PSEP1 Probable periplasmic serine endop...1640.15     39.3     24     42GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
51B4N937    434   HTRA2_DROWI Serine protease HTRA2, mitochondr...3340.0000000004     67     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
52A4IHA1    460   HTRA1_XENTR Serine protease HTRA1 OS=Xenopus ...3190.0000000004     67     27     45GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
53B4PST0    422   HTRA2_DROYA Serine protease HTRA2, mitochondr...3270.0000000004     66.6     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54Q8YG32    513   DEGPL_BRUME Probable periplasmic serine endop...2590.0000000006     66.6     28     44GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
55P0A3Z5    513   DEGPL_BRUSU Probable periplasmic serine endop...2590.0000000006     66.6     28     44GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
56P0C114    513   DEGPL_BRUAB Probable periplasmic serine endop...2590.0000000006     66.6     28     44GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
57Q2YMX6    513   DEGPL_BRUA2 Probable periplasmic serine endop...2590.0000000006     66.6     28     44GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
58B0KV30    477   DEGPL_PSEPG Probable periplasmic serine endop...1630.24     38.9     22     41GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
59P83110    453   HTRA3_HUMAN Serine protease HTRA3 OS=Homo sap...2890.000000003     63.9     26     42GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
60E1BJW1    484   HTRA4_BOVIN Serine protease HTR4 OS=Bos tauru...3250.000000003     63.9     26     44GO:0005576; C:extracellular region; IEA:InterPro.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
61D3ZKF5    488   HTRA4_RAT Serine protease HTR4 OS=Rattus norv...3070.000000003     63.9     24     44GO:0005576; C:extracellular region; IEA:InterPro.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
records
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