Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL104C
Length:
619
Number of sequences:
5887
Description:
YNL104C LEU4 SGDID:S000005048, Chr XIV from 426754-424895, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q56216    331   LEU1_THETH 2-isopropylmalate synthase OS=Ther...3280.0000000001     67     26     42
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
422A3CUF2    503   CIMA_METMJ Putative (R)-citramalate synthase ...3680.0000000003     66.6     24     38
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
423Q8TKQ6    405   AKSA_METAC Putative homocitrate synthase AksA...4060.0000000004     65.9     22     39
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
424Q971S5    460   HOSA_SULTO Putative homocitrate synthase OS=S...3070.0000000004     65.9     21     41GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
425P58967    405   AKSA_METMA Putative homocitrate synthase AksA...3080.0000000007     65.1     25     40
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
426Q8TJJ1    483   CIMA_METAC Putative (R)-citramalate synthase ...5500.0000000009     65.1     23     39
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
427Q9WZ22    538   LY41_THEMA Uncharacterized AIPM/Hcit synthase...5710.000000006     62.4     21     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
428Q58787    491   CIMA_METJA (R)-citramalate synthase CimA OS=J...5480.000000006     62.4     21     39
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
429C3MPM7    461   HOSA_SULIL Putative homocitrate synthase OS=S...3070.00000001     61.2     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
430P05342    385   NIFV_AZOVI Homocitrate synthase OS=Azotobacte...3750.00000001     60.8     23     38
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
431C3NDV7    461   HOSA_SULIY Putative homocitrate synthase OS=S...3070.00000002     60.8     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
432C3NHU6    461   HOSA_SULIN Putative homocitrate synthase OS=S...3070.00000002     60.8     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
433C3MYM1    461   HOSA_SULIM Putative homocitrate synthase OS=S...3070.00000002     60.8     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
434C4KGW9    461   HOSA_SULIK Putative homocitrate synthase OS=S...3070.00000002     60.8     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
435C3N5A3    461   HOSA_SULIA Putative homocitrate synthase OS=S...3070.00000002     60.8     23     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
436O59390    361   HOSA_PYRHO Putative homocitrate synthase OS=N...3230.00000004     59.3     24     38
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
437Q97ZE0    461   HOSA_SULSO Putative homocitrate synthase OS=P...3070.0000002     57.4     24     38GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
438Q52070    400   NIFV_ENTAG Homocitrate synthase OS=Enterobact...4010.0000003     56.6     21     36
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
439Q9V1J1    361   HOSA_PYRAB Putative homocitrate synthase OS=P...3160.0000004     56.2     22     38
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0046912; F:transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
440B9L2J0    356   HOA_THERP 4-hydroxy-2-oxovalerate aldolase OS...2860.000001     54.7     23     37
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
441P74269    547   LY41_SYNY3 Uncharacterized AIPM/Hcit synthase...3410.000001     54.7     24     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
442P23122    382   NIFV_AZOCH Homocitrate synthase OS=Azotobacte...3750.000002     53.9     23     38
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
443P58637    376   NIFV2_NOSS1 Homocitrate synthase 2 OS=Nostoc ...3690.000005     52.8     24     37
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
444O86511    534   LY41_STRCO Uncharacterized AIPM/Hcit synthase...4100.000009     52.4     22     36
GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
445Q07179    382   NIFV_RHOCA Homocitrate synthase OS=Rhodobacte...4020.000009     52     23     36
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
446Q53WI0    347   HOA_THET8 4-hydroxy-2-oxovalerate aldolase OS...3140.00003     50.1     23     38
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
447P58966    483   CIMA_METMA Putative (R)-citramalate synthase ...4710.00003     50.4     23     38
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
448Q47884    351   NIFV_FRAAL Homocitrate synthase OS=Frankia al...3470.00005     49.3     23     37
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
449Q44290    377   NIFV1_NOSS1 Homocitrate synthase 1 OS=Nostoc ...2320.00008     48.9     26     39
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
450Q01181    391   NIFV_RHOSH Homocitrate synthase OS=Rhodobacte...3220.0001     48.5     23     38
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
451Q8RCF9    384   LEU12_THETN 2-isopropylmalate synthase 2 OS=1...3550.0002     48.1     22     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.::GO:0004410; F:homocitrate synthase activity; IEA:InterPro.
GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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