Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL093W
Length:
220
Number of sequences:
5887
Description:
YNL093W YPT53 SGDID:S000005037, Chr XIV from 449868-450530, Genome Release 64-1-1, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601Q5R6S2    199   DIRA2_PONAB GTP-binding protein Di-Ras2 OS=Po...1642e-16     78.6     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
602P15153    192   RAC2_HUMAN Ras-related C3 botulinum toxin sub...1842e-16     78.6     30     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
603Q9SJZ5    176   RAA4E_ARATH Putative Ras-related protein RABA...1632e-16     78.2     34     45
GO:0005525; F:GTP binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
604Q96HU8    199   DIRA2_HUMAN GTP-binding protein Di-Ras2 OS=Ho...1642e-16     78.2     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
605Q9SBJ6    197   RAC6_ARATH Rac-like GTP-binding protein ARAC6...1703e-16     78.2     32     53GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
606Q95KD9    199   DIRA2_MACFA GTP-binding protein Di-Ras2 OS=Ma...1643e-16     78.2     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
607A5D7J5    255   RHOU_BOVIN Rho-related GTP-binding protein Rh...1693e-16     78.6     32     52GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
608P62071    204   RRAS2_MOUSE Ras-related protein R-Ras2 OS=Mus...1543e-16     77.8     34     50GO:0005622; C:intracellular; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.
609P62070    204   RRAS2_HUMAN Ras-related protein R-Ras2 OS=Hom...1543e-16     77.8     34     50GO:0005783; C:endoplasmic reticulum; NAS:ProtInc.::GO:0005886; C:plasma membrane; NAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
610Q55CA9    214   RASZ_DICDI Ras-like protein rasZ OS=Dictyoste...1613e-16     77.8     29     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
611Q9HBH0    211   RHOF_HUMAN Rho-related GTP-binding protein Rh...1733e-16     77.8     28     51GO:0005856; C:cytoskeleton; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
612Q55CB9    229   RASV_DICDI Ras-like protein rasV OS=Dictyoste...1843e-16     78.2     28     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
613Q23862    223   RACE_DICDI Rho-related protein racE OS=Dictyo...1733e-16     77.8     28     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
614Q55CB0    213   RASU_DICDI Ras-like protein rasU OS=Dictyoste...1654e-16     77.8     27     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
615Q35638    197   RHO1_PEA Rac-like GTP-binding protein RHO1 OS...1674e-16     77.4     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
616Q05144    192   RAC2_MOUSE Ras-related C3 botulinum toxin sub...1845e-16     77     30     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0030031; P:cell projection assembly; IDA:MGI.::GO:0006935; P:chemotaxis; IDA:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
617P20171    189   RASH_RAT GTPase HRas OS=Rattus norvegicus (Ra...1525e-16     77     30     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:RGD.::GO:0007265; P:Ras protein signal transduction; IMP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
618Q61411    189   RASH_MOUSE GTPase HRas OS=Mus musculus (Mouse...1525e-16     77     30     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
619P01112    189   RASH_HUMAN GTPase HRas OS=Homo sapiens (Human...1525e-16     77     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0090398; P:cellular senescence; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
620P22122    192   RHO_DISOM Ras-like GTP-binding protein O-RHO ...1695e-16     77     31     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
621Q00245    231   RHO3_YEAST GTP-binding protein RHO3 OS=Saccha...1356e-16     77.4     36     53GO:0005933; C:cellular bud; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; IDA:SGD.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0045921; P:positive regulation of exocytosis; IMP:SGD.::GO:0090338; P:positive regulation of formin-nucleated actin cable assembly; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
622Q55CC0    216   RASW_DICDI Ras-like protein rasW OS=Dictyoste...1616e-16     77     29     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
623Q8VHP8    278   RB40B_MOUSE Ras-related protein Rab-40B OS=Mu...1676e-16     77.8     30     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
624O82481    215   RAC10_ARATH Rac-like GTP-binding protein ARAC...1766e-16     77     28     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
625O96390    193   RACF1_DICDI Rho-related protein racF1 OS=Dict...1687e-16     76.6     30     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
626Q9TU25    192   RAC2_BOVIN Ras-related C3 botulinum toxin sub...1847e-16     76.6     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
627P10833    218   RRAS_MOUSE Ras-related protein R-Ras OS=Mus m...1987e-16     77     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
628P60764    192   RAC3_MOUSE Ras-related C3 botulinum toxin sub...1777e-16     76.6     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0030031; P:cell projection assembly; ISS:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
629P60763    192   RAC3_HUMAN Ras-related C3 botulinum toxin sub...1777e-16     76.6     30     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0031941; C:filamentous actin; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0030031; P:cell projection assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
630Q9ER71    214   RHOJ_MOUSE Rho-related GTP-binding protein Rh...1187e-16     77     34     56GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
631P40792    192   RAC1_DROME Ras-related protein Rac1 OS=Drosop...1807e-16     76.6     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007413; P:axonal fasciculation; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; NAS:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007516; P:hemocyte development; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035320; P:imaginal disc-derived wing hair site selection; IMP:FlyBase.::GO:0002433; P:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; IDA:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0008078; P:mesodermal cell migration; IMP:FlyBase.::GO:0007017; P:microtubule-based process; NAS:FlyBase.::GO:0016335; P:morphogenesis of larval imaginal disc epithelium; TAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048747; P:muscle fiber development; IMP:FlyBase.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0051450; P:myoblast proliferation; IMP:FlyBase.::GO:0010593; P:negative regulation of lamellipodium assembly; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0051963; P:regulation of synapse assembly; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0042052; P:rhabdomere development; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007426; P:tracheal outgrowth, open tracheal system; IGI:FlyBase.::GO:0007419; P:ventral cord development; IMP:FlyBase.
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