UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL093W

Length:

220

Number of sequences:

5887

Description:

YNL093W YPT53 SGDID:S000005037, Chr XIV from 449868-450530, Genome Release 64-1-1, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
541	Q9NX57	234	RAB20_HUMAN Ras-related protein Rab-20 OS=Hom...	229	4e-18	84	28	45	GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
542	Q68Y52	214	RAC2_ORYSJ Rac-like GTP-binding protein 2 OS=...	170	4e-18	83.6	31	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
543	Q38912	198	RAC3_ARATH Rac-like GTP-binding protein ARAC3...	167	4e-18	83.2	33	50	GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030427; C:site of polarized growth; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
544	P70425	217	RIT2_MOUSE GTP-binding protein Rit2 OS=Mus mu...	164	5e-18	83.2	34	52	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
545	Q17QI8	236	RHOV_BOVIN Rho-related GTP-binding protein Rh...	178	5e-18	83.6	30	48	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
546	P34149	192	RACC_DICDI Rho-related protein racC OS=Dictyo...	171	6e-18	82.8	30	54	GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
									GO:0016477; P:cell migration; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0045184; P:establishment of protein localization; IMP:dictyBase.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
547	Q54FG4	232	RABP_DICDI Ras-related protein RabP OS=Dictyo...	150	6e-18	83.2	33	50	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
548	O04369	197	RAC1_LOTJA Rac-like GTP-binding protein RAC1 ...	167	9e-18	82.4	31	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
549	Q54SV1	236	RABY_DICDI Ras-related protein RabY OS=Dictyo...	168	9e-18	82.8	30	51	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
550	Q9P8V0	259	RHO4_ASHGO GTP-binding protein RHO4 OS=Y-1056...	171	1e-17	82.8	31	50	GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
551	P41915	225	RAN_TETTH GTP-binding nuclear protein Ran OS=...	152	1e-17	82	33	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
552	Q55CB7	216	RASY_DICDI Ras-like protein rasY OS=Dictyoste...	173	1e-17	82	30	55	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:dictyBase.
									GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
553	Q9Z1Y0	236	RHOV_RAT Rho-related GTP-binding protein RhoV...	173	2e-17	81.6	31	48	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
554	Q6EP31	197	RAC5_ORYSJ Rac-like GTP-binding protein 5 OS=...	167	2e-17	81.3	32	50
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
555	Q8VDU1	236	RHOV_MOUSE Rho-related GTP-binding protein Rh...	173	2e-17	81.6	31	48	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
556	Q96L33	236	RHOV_HUMAN Rho-related GTP-binding protein Rh...	173	2e-17	81.6	31	48	GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
557	Q5BJQ5	217	RIT2_RAT GTP-binding protein Rit2 OS=Rattus n...	164	3e-17	81.3	34	51	GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
558	Q41254	196	RAC9_GOSHI Rac-like GTP-binding protein RAC9 ...	168	3e-17	80.5	30	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
559	Q55CB8	213	RASX_DICDI Ras-like protein rasX OS=Dictyoste...	183	3e-17	80.9	29	54	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
									GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
560	Q40220	196	RAC2_LOTJA Rac-like GTP-binding protein RAC2 ...	170	4e-17	80.5	30	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
561	Q2HJG3	191	RHOH_BOVIN Rho-related GTP-binding protein Rh...	174	4e-17	80.5	31	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
562	Q9VUN3	217	RANL_DROME GTP-binding nuclear protein Ran-li...	167	4e-17	80.5	27	51	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
563	P24406	193	RHOA_CANFA Transforming protein RhoA OS=Canis...	170	4e-17	80.1	32	52	GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
564	Q9GPS0	201	RACG_DICDI Rho-related protein racG OS=Dictyo...	170	4e-17	80.5	32	52	GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0006909; P:phagocytosis; IDA:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0032314; P:regulation of Rac GTPase activity; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
565	P62747	196	RHOB_RAT Rho-related GTP-binding protein RhoB...	169	4e-17	80.1	32	52	GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
									GO:0005525; F:GTP binding; TAS:UniProtKB.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; ISS:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006927; P:transformed cell apoptotic process; ISS:UniProtKB.
566	P62746	196	RHOB_MOUSE Rho-related GTP-binding protein Rh...	169	4e-17	80.1	32	52	GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:MGI.
									GO:0019003; F:GDP binding; IDA:MGI.::GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IDA:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; ISS:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006927; P:transformed cell apoptotic process; IDA:UniProtKB.
567	P62745	196	RHOB_HUMAN Rho-related GTP-binding protein Rh...	169	4e-17	80.1	32	52	GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
									GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.::GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.::GO:0006927; P:transformed cell apoptotic process; ISS:UniProtKB.
568	Q3ZBW5	196	RHOB_BOVIN Rho-related GTP-binding protein Rh...	169	4e-17	80.1	32	52	GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; ISS:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
569	Q5RCK9	193	RHOC_PONAB Rho-related GTP-binding protein Rh...	172	5e-17	80.1	33	52	GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
570	Q62159	193	RHOC_MOUSE Rho-related GTP-binding protein Rh...	172	5e-17	80.1	33	52	GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
571	P08134	193	RHOC_HUMAN Rho-related GTP-binding protein Rh...	172	5e-17	80.1	33	52	GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
									GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0033205; P:cell cycle cytokinesis; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.

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