Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9QSK1    1132   TOP2_IIV6 DNA topoisomerase 2 OS=Invertebrate...11133e-175     560     35     52GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
32Q196X4    1113   TOP2_IIV3 DNA topoisomerase 2 OS=Invertebrate...10733e-156     509     32     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
33P0C9C0    1192   TOP2_ASFP4 DNA topoisomerase 2 OS=Pr4/1996) (...12413e-88     317     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
34P0C9C1    1192   TOP2_ASFWA DNA topoisomerase 2 OS=(ASFV). GN=...12431e-87     315     27     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
35Q00942    1192   TOP2_ASFB7 DNA topoisomerase 2 OS=(ASFV). GN=...12412e-86     311     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
36P34203    1191   TOP2_ASFM2 DNA topoisomerase 2 OS=African swi...12393e-86     311     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
37P0C9C2    1192   TOP2_ASFK5 DNA topoisomerase 2 OS=African swi...12393e-85     308     26     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
38O67137    792   GYRB_AQUAE DNA gyrase subunit B OS=Aquifex ae...5831e-40     166     29     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
39P77993    636   GYRB_THEMA DNA gyrase subunit B OS=Thermotoga...6757e-39     159     27     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
40P09176    516   TOPL_BPT4 DNA topoisomerase large subunit OS=...4998e-38     154     30     46GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
41P0A2I5    630   PARE_SALTY DNA topoisomerase 4 subunit B OS=S...6878e-37     152     24     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
42P0A2I6    630   PARE_SALTI DNA topoisomerase 4 subunit B OS=S...6878e-37     152     24     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
43P43703    632   PARE_HAEIN DNA topoisomerase 4 subunit B OS=H...6533e-36     150     25     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
44P20083    630   PARE_ECOLI DNA topoisomerase 4 subunit B OS=E...6434e-36     150     25     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.
GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0030541; P:plasmid partitioning; IDA:EcoliWiki.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0007062; P:sister chromatid cohesion; IMP:EcoliWiki.
45P22447    650   GYRB_MYCPN DNA gyrase subunit B OS=Mycoplasma...6877e-34     143     27     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
46P47249    650   GYRB_MYCGE DNA gyrase subunit B OS=Mycoplasma...6762e-33     141     28     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
47O87667    769   GYRB_CAMJE DNA gyrase subunit B OS=Campylobac...5491e-32     140     29     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
48P94604    637   GYRB_CLOAB DNA gyrase subunit B OS=5710 / VKM...5852e-32     139     28     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
49P07065    442   TOP5_BPT4 DNA topoisomerase medium subunit OS...3712e-32     137     30     49GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
50O84193    804   GYRB_CHLTR DNA gyrase subunit B OS=Chlamydia ...5787e-32     138     27     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
51Q9PKK3    804   GYRB_CHLMU DNA gyrase subunit B OS=Chlamydia ...6168e-32     138     26     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
52O08399    637   GYRB_TREPA DNA gyrase subunit B OS=Treponema ...6332e-31     135     25     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006265; P:DNA topological change; IEA:InterPro.
53Q59961    647   PARE_STRPN DNA topoisomerase 4 subunit B OS=S...6423e-31     135     26     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
54Q9HUJ8    629   PARE_PSEAE DNA topoisomerase 4 subunit B OS=1...6833e-31     135     24     41GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
55P94281    692   GYRB_BARBK DNA gyrase subunit B OS=Bartonella...6479e-31     134     25     41GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
56Q92H87    807   GYRB_RICCN DNA gyrase subunit B OS=Rickettsia...5892e-30     134     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
57P34031    640   GYRB_SPICI DNA gyrase subunit B OS=Spiroplasm...5673e-30     132     29     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
58Q4UKX5    808   GYRB_RICFE DNA gyrase subunit B OS=Rickettsia...5943e-30     133     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
59Q1RHT8    808   GYRB_RICBR DNA gyrase subunit B OS=Rickettsia...6024e-30     133     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
60P13364    806   GYRB_PSEPU DNA gyrase subunit B OS=Pseudomona...5876e-30     132     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
61O54479    695   PARE_CAUCR DNA topoisomerase 4 subunit B OS=C...6486e-30     132     26     42GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
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