| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations | 
					31 | Q9QSK1 | 1132 | TOP2_IIV6 DNA topoisomerase 2 OS=Invertebrate... | 1113 | 3e-175 | 560 | 35 | 52 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 32 | Q196X4 | 1113 | TOP2_IIV3 DNA topoisomerase 2 OS=Invertebrate... | 1073 | 3e-156 | 509 | 32 | 51 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 33 | P0C9C0 | 1192 | TOP2_ASFP4 DNA topoisomerase 2 OS=Pr4/1996) (... | 1241 | 3e-88 | 317 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 34 | P0C9C1 | 1192 | TOP2_ASFWA DNA topoisomerase 2 OS=(ASFV). GN=... | 1243 | 1e-87 | 315 | 27 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 35 | Q00942 | 1192 | TOP2_ASFB7 DNA topoisomerase 2 OS=(ASFV). GN=... | 1241 | 2e-86 | 311 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 36 | P34203 | 1191 | TOP2_ASFM2 DNA topoisomerase 2 OS=African swi... | 1239 | 3e-86 | 311 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 37 | P0C9C2 | 1192 | TOP2_ASFK5 DNA topoisomerase 2 OS=African swi... | 1239 | 3e-85 | 308 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 38 | O67137 | 792 | GYRB_AQUAE DNA gyrase subunit B OS=Aquifex ae... | 583 | 1e-40 | 166 | 29 | 45 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 39 | P77993 | 636 | GYRB_THEMA DNA gyrase subunit B OS=Thermotoga... | 675 | 7e-39 | 159 | 27 | 45 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 40 | P09176 | 516 | TOPL_BPT4 DNA topoisomerase large subunit OS=... | 499 | 8e-38 | 154 | 30 | 46 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 41 | P0A2I5 | 630 | PARE_SALTY DNA topoisomerase 4 subunit B OS=S... | 687 | 8e-37 | 152 | 24 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 42 | P0A2I6 | 630 | PARE_SALTI DNA topoisomerase 4 subunit B OS=S... | 687 | 8e-37 | 152 | 24 | 43 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 43 | P43703 | 632 | PARE_HAEIN DNA topoisomerase 4 subunit B OS=H... | 653 | 3e-36 | 150 | 25 | 44 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 44 | P20083 | 630 | PARE_ECOLI DNA topoisomerase 4 subunit B OS=E... | 643 | 4e-36 | 150 | 25 | 45 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0030541; P:plasmid partitioning; IDA:EcoliWiki.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0007062; P:sister chromatid cohesion; IMP:EcoliWiki. | 45 | P22447 | 650 | GYRB_MYCPN DNA gyrase subunit B OS=Mycoplasma... | 687 | 7e-34 | 143 | 27 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 46 | P47249 | 650 | GYRB_MYCGE DNA gyrase subunit B OS=Mycoplasma... | 676 | 2e-33 | 141 | 28 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 47 | O87667 | 769 | GYRB_CAMJE DNA gyrase subunit B OS=Campylobac... | 549 | 1e-32 | 140 | 29 | 44 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 48 | P94604 | 637 | GYRB_CLOAB DNA gyrase subunit B OS=5710 / VKM... | 585 | 2e-32 | 139 | 28 | 45 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 49 | P07065 | 442 | TOP5_BPT4 DNA topoisomerase medium subunit OS... | 371 | 2e-32 | 137 | 30 | 49 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 50 | O84193 | 804 | GYRB_CHLTR DNA gyrase subunit B OS=Chlamydia ... | 578 | 7e-32 | 138 | 27 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 51 | Q9PKK3 | 804 | GYRB_CHLMU DNA gyrase subunit B OS=Chlamydia ... | 616 | 8e-32 | 138 | 26 | 42 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 52 | O08399 | 637 | GYRB_TREPA DNA gyrase subunit B OS=Treponema ... | 633 | 2e-31 | 135 | 25 | 42 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 53 | Q59961 | 647 | PARE_STRPN DNA topoisomerase 4 subunit B OS=S... | 642 | 3e-31 | 135 | 26 | 44 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 54 | Q9HUJ8 | 629 | PARE_PSEAE DNA topoisomerase 4 subunit B OS=1... | 683 | 3e-31 | 135 | 24 | 41 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 55 | P94281 | 692 | GYRB_BARBK DNA gyrase subunit B OS=Bartonella... | 647 | 9e-31 | 134 | 25 | 41 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 56 | Q92H87 | 807 | GYRB_RICCN DNA gyrase subunit B OS=Rickettsia... | 589 | 2e-30 | 134 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 57 | P34031 | 640 | GYRB_SPICI DNA gyrase subunit B OS=Spiroplasm... | 567 | 3e-30 | 132 | 29 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 58 | Q4UKX5 | 808 | GYRB_RICFE DNA gyrase subunit B OS=Rickettsia... | 594 | 3e-30 | 133 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 59 | Q1RHT8 | 808 | GYRB_RICBR DNA gyrase subunit B OS=Rickettsia... | 602 | 4e-30 | 133 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. | 60 | P13364 | 806 | GYRB_PSEPU DNA gyrase subunit B OS=Pseudomona... | 587 | 6e-30 | 132 | 26 | 43 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 61 | O54479 | 695 | PARE_CAUCR DNA topoisomerase 4 subunit B OS=C... | 648 | 6e-30 | 132 | 26 | 42 | GO:0005694; C:chromosome; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006265; P:DNA topological change; IEA:InterPro. |