Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q5YLB5    935   GYRA_NICBE DNA gyrase subunit A, chloroplasti...1880.000000000007     74.3     29     49GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
242P48369    922   GYRA_AERSA DNA gyrase subunit A OS=Aeromonas ...3430.00000000001     73.6     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
243Q89AS3    847   GYRA_BUCBP DNA gyrase subunit A OS=Buchnera a...1760.00000000001     73.2     29     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
244P35810    903   GYRA_FIBSS DNA gyrase subunit A OS=Fibrobacte...1870.00000000003     72     28     47GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
245P43702    747   PARC_HAEIN DNA topoisomerase 4 subunit A OS=H...3830.00000000004     71.6     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
246Q9X3Y3    404   GYRB_BACCE DNA gyrase subunit B OS=Bacillus c...4260.00000000008     69.7     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
247Q45066    806   PARC_BACSU DNA topoisomerase 4 subunit A OS=B...1720.00000000009     70.5     28     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
248Q9X3Y5    404   GYRB_BACMY DNA gyrase subunit B OS=Bacillus m...4270.0000000001     69.3     26     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
249Q44272    390   GYRB2_ACILW DNA gyrase subunit B OS=Acinetoba...4110.0000000004     67.4     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
250Q44088    390   GYRB1_ACILW DNA gyrase subunit B OS=Acinetoba...4110.0000000004     67.4     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
251P0DG06    819   PARC_STRP3 DNA topoisomerase 4 subunit A OS=S...1870.0000000005     67.8     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
252Q9L7Q4    819   PARC_STRP1 DNA topoisomerase 4 subunit A OS=S...1870.0000000005     67.8     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
253P0AFI4    752   PARC_SHIFL DNA topoisomerase 4 subunit A OS=S...3610.0000000006     67.8     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
254P0AFI2    752   PARC_ECOLI DNA topoisomerase 4 subunit A OS=E...3610.0000000006     67.8     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:EcoliWiki.::GO:0019897; C:extrinsic to plasma membrane; IDA:EcoliWiki.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006265; P:DNA topological change; IDA:EcoliWiki.::GO:0006261; P:DNA-dependent DNA replication; IDA:EcoliWiki.::GO:0030541; P:plasmid partitioning; IDA:EcoliWiki.::GO:0007062; P:sister chromatid cohesion; IMP:EcoliWiki.
255P0AFI3    752   PARC_ECO57 DNA topoisomerase 4 subunit A OS=E...3610.0000000006     67.8     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
256Q5XCJ9    819   PARC_STRP6 DNA topoisomerase 4 subunit A OS=S...1870.0000000006     67.8     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
257Q8P1B3    819   PARC_STRP8 DNA topoisomerase 4 subunit A OS=S...1870.0000000007     67.4     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
258Q1MQ89    820   GYRA_LAWIP DNA gyrase subunit A OS=Lawsonia i...2040.0000000009     67     27     47GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
259P72525    823   PARC_STRPN DNA topoisomerase 4 subunit A OS=S...1720.0000000009     67     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
260Q9CAF6    950   GYRA_ARATH Probable DNA gyrase subunit A, chl...3480.000000001     67     26     43GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009295; C:nucleoid; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
261P0DG07    819   PARC_STRPQ DNA topoisomerase 4 subunit A OS=S...1870.000000001     66.6     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
262P26973    752   PARC_SALTY DNA topoisomerase 4 subunit A OS=S...3640.000000001     66.6     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
263Q9HUK1    754   PARC_PSEAE DNA topoisomerase 4 subunit A OS=1...1720.00000001     63.5     27     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
264Q44065    388   GYRB_ACIHA DNA gyrase subunit B OS=Acinetobac...4160.00000001     62.4     25     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
265Q44274    389   GYRB_ACIGB DNA gyrase subunit B OS=Acinetobac...4100.00000002     62     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
266Q44080    388   GYRB_ACIJU DNA gyrase subunit B OS=Acinetobac...4210.00000002     62     25     41GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
267Q43907    388   GYRB_ACIBA DNA gyrase subunit B OS=Acinetobac...4060.00000002     62     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
268P22840    182   GYRB_PROMI DNA gyrase subunit B OS=Proteus mi...1500.00000004     58.5     29     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
269A0QPN2    677   Y457_MYCS2 DNA gyrase subunit B-like protein ...3450.0000002     59.3     22     39GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
270Q44271    388   GYRB_ACIG6 DNA gyrase subunit B OS=Acinetobac...4200.0000002     58.5     24     41GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
271Q44081    389   GYRB_ACIJO DNA gyrase subunit B OS=Acinetobac...4090.0000003     57.8     24     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
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