Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211P0C559    675   GYRB_MYCSM DNA gyrase subunit B OS=Mycobacter...1700.000000001     66.2     29     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
212A0QNE0    675   GYRB_MYCS2 DNA gyrase subunit B OS=Mycobacter...1700.000000001     66.2     29     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
213P48374    768   PARC_NEIGO DNA topoisomerase 4 subunit A OS=N...2090.0000000000006     77.4     31     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
214P0AES5    875   GYRA_SHIFL DNA gyrase subunit A OS=Shigella f...3480.0000000000008     77     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
215P0AES4    875   GYRA_ECOLI DNA gyrase subunit A OS=Escherichi...3480.0000000000008     77     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:EcoliWiki.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:EcoliWiki.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0007059; P:chromosome segregation; IBA:RefGenome.::GO:0006265; P:DNA topological change; IMP:EcoliWiki.::GO:0006261; P:DNA-dependent DNA replication; IMP:EcoliWiki.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0042493; P:response to drug; IMP:EcoliWiki.
216P37411    878   GYRA_SALTY DNA gyrase subunit A OS=Salmonella...3490.0000000000009     77     26     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
217Q59533    678   GYRB_MYCLE DNA gyrase subunit B OS=Mycobacter...1540.008     44.3     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
218P43700    880   GYRA_HAEIN DNA gyrase subunit A OS=Haemophilu...3410.000000000001     77     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
219P14829    876   GYRA_KLEOX DNA gyrase subunit A OS=Klebsiella...3480.000000000001     76.6     26     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
220Q0BST5    940   GYRA_GRABC DNA gyrase subunit A OS=Granulibac...3420.000000000001     76.6     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
221Q5HG64    800   PARC_STAAC DNA topoisomerase 4 subunit A OS=S...1870.000000000001     76.3     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
222Q2FYS4    800   PARC_STAA8 DNA topoisomerase 4 subunit A OS=S...1870.000000000001     76.3     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
223Q6G9K4    800   PARC_STAAS DNA topoisomerase 4 subunit A OS=S...1870.000000000001     76.3     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
224Q93KF4    800   PARC_STAAN DNA topoisomerase 4 subunit A OS=S...1870.000000000001     76.3     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
225A1SCM2    922   GYRA_NOCSJ DNA gyrase subunit A OS=Nocardioid...1680.000000000002     76.3     30     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
226Q8NWU8    800   PARC_STAAW DNA topoisomerase 4 subunit A OS=S...1870.000000000002     76.3     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
227P41513    878   GYRA_ERWCA DNA gyrase subunit A OS=Erwinia ca...3480.000000000002     75.9     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
228Q6GH50    800   PARC_STAAR DNA topoisomerase 4 subunit A OS=S...1870.000000000002     75.9     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
229Q8CSN8    800   PARC_STAES DNA topoisomerase 4 subunit A OS=S...1870.000000000002     75.5     27     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
230Q5HPI5    800   PARC_STAEQ DNA topoisomerase 4 subunit A OS=S...1870.000000000002     75.5     27     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
231Q9L7Q5    828   GYRA_STRP1 DNA gyrase subunit A OS=Streptococ...3300.000000000003     75.5     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
232P0DG03    828   GYRA_STRPQ DNA gyrase subunit A OS=Streptococ...3300.000000000003     75.1     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
233P0DG02    828   GYRA_STRP3 DNA gyrase subunit A OS=Streptococ...3300.000000000003     75.1     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
234Q8P116    828   GYRA_STRP8 DNA gyrase subunit A OS=Streptococ...3430.000000000003     75.1     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
235Q5XC58    828   GYRA_STRP6 DNA gyrase subunit A OS=Streptococ...3300.000000000003     75.1     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
236Q931S2    800   PARC_STAAM DNA topoisomerase 4 subunit A OS=S...1870.000000000003     75.1     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
237P0C1U9    800   PARC_STAAU DNA topoisomerase 4 subunit A OS=S...1870.000000000004     74.7     28     51GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
238P57277    830   GYRA_BUCAI DNA gyrase subunit A OS=(Acyrthosi...1810.000000000004     74.7     29     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
239Q8K9W2    825   GYRA_BUCAP DNA gyrase subunit A OS=Buchnera a...1760.000000000006     74.3     29     50GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
240Q7XZF7    939   GYRA_ORYSJ Probable DNA gyrase subunit A, chl...3500.000000000006     74.3     27     43GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
241Q5YLB5    935   GYRA_NICBE DNA gyrase subunit A, chloroplasti...1880.000000000007     74.3     29     49GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
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