Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181B2S0D7    810   GYRA_BORHD DNA gyrase subunit A OS=Borrelia h...1760.000000000000004     84.7     28     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
182P34030    227   GYRA_SPICI DNA gyrase subunit A OS=Spiroplasm...2030.000000000000004     80.9     29     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
183B3PN30    898   GYRA_MYCA5 DNA gyrase subunit A OS=Mycoplasma...3650.000000000000005     84.3     28     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
184P0C5C5    675   GYRB_MYCTU DNA gyrase subunit B OS=Mycobacter...1640.000005     54.7     27     43GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IDA:MTBBASE.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE.::GO:0046982; F:protein heterodimerization activity; IPI:MTBBASE.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.
185A5TY73    675   GYRB_MYCTA DNA gyrase subunit B OS=Mycobacter...1640.000005     54.7     27     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
186P48372    923   GYRA_PSEAE DNA gyrase subunit A OS=12228). GN...3490.000000000000006     84.3     28     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
187P77966    1078   GYRB_SYNY3 DNA gyrase subunit B OS=Synechocys...3810.0000003     59.3     24     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
188O54478    759   PARC_CAUCR DNA topoisomerase 4 subunit A OS=C...1960.000000000000007     83.6     30     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
189O84192    836   GYRA_CHLTR DNA gyrase subunit A OS=Chlamydia ...3430.000000000000007     83.6     26     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
190O50628    833   GYRA_BACHD DNA gyrase subunit A OS=9153 / C-1...1980.00000000000001     82.8     30     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
191P47250    836   GYRA_MYCGE DNA gyrase subunit A OS=Mycoplasma...2040.00000000000001     82.8     28     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
192P48371    916   GYRA_NEIGO DNA gyrase subunit A OS=Neisseria ...4060.00000000000002     82.8     26     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
193B0S912    843   GYRA_LEPBA DNA gyrase subunit A OS=Leptospira...1760.00000000000002     82.4     31     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
194P41080    905   GYRA_RICPR DNA gyrase subunit A OS=Rickettsia...1770.00000000000003     81.6     31     50GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
195Q9L7L3    677   GYRB_MYCPA DNA gyrase subunit B OS=Mycobacter...1680.003     45.8     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
196P35885    857   GYRA_STRCO DNA gyrase subunit A OS=Streptomyc...1630.00000000000004     81.3     32     50GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:RefGenome.
GO:0007059; P:chromosome segregation; ISS:RefGenome.::GO:0006265; P:DNA topological change; ISS:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; ISS:RefGenome.
197Q07702    838   GYRA_MYCTU DNA gyrase subunit A OS=Mycobacter...3220.00000000000004     81.3     28     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IDA:MTBBASE.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE.::GO:0046982; F:protein heterodimerization activity; IPI:MTBBASE.
GO:0006265; P:DNA topological change; IDA:MTBBASE.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
198P75352    789   PARC_MYCPN DNA topoisomerase 4 subunit A OS=M...2440.00000000000005     80.9     27     47GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
199O83051    813   GYRA_TREPA DNA gyrase subunit A OS=Treponema ...1980.00000000000005     80.9     30     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
200P22446    839   GYRA_MYCPN DNA gyrase subunit A OS=Mycoplasma...2220.00000000000006     80.9     27     50GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
201Q68XG2    905   GYRA_RICTY DNA gyrase subunit A OS=Rickettsia...1640.00000000000007     80.5     32     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
202Q55738    860   GYRA_SYNY3 DNA gyrase subunit A OS=Synechocys...3820.00000000000008     80.5     24     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
203Q4UKM1    906   GYRA_RICFE DNA gyrase subunit A OS=Rickettsia...1820.0000000000002     79     30     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
204Q8DPM2    822   GYRA_STRR6 DNA gyrase subunit A OS=Streptococ...3610.0000000000003     78.6     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
205P72524    822   GYRA_STRPN DNA gyrase subunit A OS=Streptococ...3610.0000000000003     78.6     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
206P73077    920   PARC_SYNY3 DNA topoisomerase 4 subunit A OS=S...1910.0000000000003     78.2     30     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
207Q92IZ6    905   GYRA_RICCN DNA gyrase subunit A OS=Rickettsia...2420.0000000000004     78.2     31     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
208Q9Z8R4    834   GYRA_CHLPN DNA gyrase subunit A OS=Chlamydia ...3430.0000000000004     78.2     26     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
209P48354    842   GYRA_MYCS2 DNA gyrase subunit A OS=Mycobacter...1670.0000000000005     77.8     32     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
210Q1RID9    905   GYRA_RICBR DNA gyrase subunit A OS=Rickettsia...1690.0000000000005     77.8     32     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
211P0C559    675   GYRB_MYCSM DNA gyrase subunit B OS=Mycobacter...1700.000000001     66.2     29     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
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