Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q5XD05    650   GYRB_STRP6 DNA gyrase subunit B OS=Streptococ...5929e-22     105     24     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
122Q9A0L0    650   GYRB_STRP1 DNA gyrase subunit B OS=Streptococ...5929e-22     105     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
123P0A4M0    648   GYRB_STRR6 DNA gyrase subunit B OS=Streptococ...5909e-21     102     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
124P0A4L9    648   GYRB_STRPN DNA gyrase subunit B OS=Streptococ...5909e-21     102     25     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
125Q9LCK0    478   GYRB_CYTAU DNA gyrase subunit B OS=Cytophaga ...4561e-20     100     28     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
126Q59189    599   PARE_BORBU DNA topoisomerase 4 subunit B OS=4...6091e-20     101     26     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
127O33367    815   GYRB_MYXXA DNA gyrase subunit B OS=Myxococcus...5635e-20     100     25     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
128Q9X3Y6    640   GYRB_BACAN DNA gyrase subunit B OS=Bacillus a...6129e-20     99.4     25     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
129P50075    684   GYRBS_STRSH DNA gyrase subunit B, novobiocin-...7052e-19     98.2     24     38GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
130P50074    677   GYRBR_STRSH DNA gyrase subunit B, novobiocin-...7005e-19     97.1     23     39GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
131P35886    686   GYRB_STRCO DNA gyrase subunit B OS=Streptomyc...7247e-19     96.3     23     39GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:RefGenome.
GO:0007059; P:chromosome segregation; ISS:RefGenome.::GO:0006265; P:DNA topological change; ISS:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; ISS:RefGenome.
132Q92JH0    738   PARC_RICCN DNA topoisomerase 4 subunit A OS=R...3642e-18     95.5     27     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
133Q9FAX2    481   GYRB_CHIJA DNA gyrase subunit B OS=Chitinopha...4593e-18     93.6     29     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
134Q4UNA0    737   PARC_RICFE DNA topoisomerase 4 subunit A OS=R...3643e-18     94.7     26     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
135Q9ZLD9    828   GYRA_HELPJ DNA gyrase subunit A OS=Helicobact...2093e-18     94.7     30     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
136P66937    644   GYRB_STAAN DNA gyrase subunit B OS=Staphyloco...6443e-18     94     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
137P66936    644   GYRB_STAAM DNA gyrase subunit B OS=Staphyloco...6443e-18     94     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
138P47719    846   GYRA_MYCGA DNA gyrase subunit A OS=Mycoplasma...1894e-18     94.4     32     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
139P0A0K7    644   GYRB_STAAW DNA gyrase subunit B OS=Staphyloco...6445e-18     93.6     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
140P0A0K8    644   GYRB_STAAU DNA gyrase subunit B OS=Staphyloco...6445e-18     93.6     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
141Q6GD85    644   GYRB_STAAS DNA gyrase subunit B OS=Staphyloco...6445e-18     93.6     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
142Q2FKQ1    644   GYRB_STAA3 DNA gyrase subunit B OS=Staphyloco...6445e-18     93.6     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
143Q1RGX8    736   PARC_RICBR DNA topoisomerase 4 subunit A OS=R...3596e-18     93.6     26     47GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
144Q6GKU0    644   GYRB_STAAR DNA gyrase subunit B OS=Staphyloco...6447e-18     93.2     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
145P48370    827   GYRA_HELPY DNA gyrase subunit A OS=pylori). G...3388e-18     93.6     26     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
146O67108    744   GYRA_AQUAE DNA gyrase subunit A OS=Aquifex ae...3998e-18     93.2     25     47GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
147D5ECW5    817   GYRA_AMICL DNA gyrase subunit A OS=Aminobacte...3711e-17     93.2     26     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
148C5CHA8    812   GYRA_KOSOT DNA gyrase subunit A OS=Kosmotoga ...2711e-17     92.8     31     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
149Q9PR63    840   GYRA_UREPA DNA gyrase subunit A OS=Ureaplasma...2181e-17     92.8     30     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
150Q5HJZ1    644   GYRB_STAAC DNA gyrase subunit B OS=Staphyloco...6441e-17     92.4     26     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
151Q9FAX1    478   GYRB_FLEEL DNA gyrase subunit B OS=Flexibacte...4702e-17     90.5     27     41GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
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