Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL088W
Length:
1428
Number of sequences:
5887
Description:
YNL088W TOP2 SGDID:S000005032, Chr XIV from 457704-461990, Genome Release 64-1-1, Verified ORF, "Topoisomerase II, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P06786    1428   TOP2_YEAST DNA topoisomerase 2 OS=Saccharomyc...14280     2935     100     100GO:0097047; C:DNA replication termination region; IPI:SGD.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000795; C:synaptonemal complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:SGD.
GO:0006333; P:chromatin assembly or disassembly; IMP:SGD.::GO:0031055; P:chromatin remodeling at centromere; IMP:SGD.::GO:0006271; P:DNA strand elongation involved in DNA replication; IMP:SGD.::GO:0006265; P:DNA topological change; IDA:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IMP:SGD.::GO:0000019; P:regulation of mitotic recombination; IMP:SGD.::GO:0097046; P:replication fork progression beyond termination site; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
2O93794    1406   TOP2_CANGA DNA topoisomerase 2 OS=NRRL Y-65) ...14120     2080     73     84GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
3Q01879    1400   TOP2_PICGU DNA topoisomerase 2 OS=1539 / NBRC...12300     1561     62     77GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
4P87078    1461   TOP2_CANAX DNA topoisomerase 2 OS=Candida alb...12210     1554     62     77GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
5P08096    1485   TOP2_SCHPO DNA topoisomerase 2 OS=Schizosacch...14400     1304     49     65GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:RefGenome.::GO:0000795; C:synaptonemal complex; ISS:RefGenome.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:PomBase.
GO:0006325; P:chromatin organization; IGI:PomBase.::GO:0006271; P:DNA strand elongation involved in DNA replication; ISS:PomBase.::GO:0006265; P:DNA topological change; IDA:PomBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; ISS:RefGenome.::GO:0007076; P:mitotic chromosome condensation; IMP:PomBase.::GO:0006312; P:mitotic recombination; ISS:RefGenome.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:PomBase.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IGI:PomBase.
6Q9Y8G8    1587   TOP2_PENCH DNA topoisomerase 2 OS=Penicillium...11940     1220     52     69GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
7O16140    1547   TOP2_BOMMO DNA topoisomerase 2 OS=Bombyx mori...12760     1117     47     65GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
8P30182    1473   TOP2_ARATH DNA topoisomerase 2 OS=Arabidopsis...11790     1096     49     66GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
9O24308    1462   TOP2_PEA DNA topoisomerase 2 OS=Pisum sativum...11730     1093     50     66GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
10Q02880    1626   TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo ...11840     1090     48     66GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
11Q64511    1612   TOP2B_MOUSE DNA topoisomerase 2-beta OS=Mus m...11840     1088     48     66GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.
GO:0007409; P:axonogenesis; IMP:MGI.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
12Q64399    1612   TOP2B_CRILO DNA topoisomerase 2-beta OS=hamst...11810     1086     49     66GO:0005694; C:chromosome; IEA:InterPro.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
13O42131    1627   TOP2B_CHICK DNA topoisomerase 2-beta OS=Gallu...11820     1086     48     66GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.
GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
14P15348    1447   TOP2_DROME DNA topoisomerase 2 OS=Drosophila ...11930     1083     47     66GO:0008623; C:chromatin accessibility complex; IDA:FlyBase.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005626; C:insoluble fraction; IDA:FlyBase.::GO:0005625; C:soluble fraction; IDA:FlyBase.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:FlyBase.::GO:0000400; F:four-way junction DNA binding; IDA:FlyBase.::GO:0003729; F:mRNA binding; IDA:FlyBase.::GO:0000182; F:rDNA binding; IDA:FlyBase.::GO:0003696; F:satellite DNA binding; IDA:FlyBase.
GO:0006342; P:chromatin silencing; IDA:FlyBase.::GO:0006265; P:DNA topological change; IDA:FlyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0051310; P:metaphase plate congression; IDA:FlyBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007076; P:mitotic chromosome condensation; IMP:FlyBase.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.
15O46374    1533   TOP2A_PIG DNA topoisomerase 2-alpha OS=Sus sc...11720     1079     49     66GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
16P11388    1531   TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo...11710     1074     48     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IMP:UniProtKB.
GO:0030263; P:apoptotic chromosome condensation; IDA:UniProtKB.::GO:0006266; P:DNA ligation; IDA:UniProtKB.::GO:0006281; P:DNA repair; NAS:UniProtKB.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0045870; P:positive regulation of retroviral genome replication; IMP:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
17P41515    1526   TOP2A_CRIGR DNA topoisomerase 2-alpha OS=Cric...11710     1074     49     65GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
18O42130    1553   TOP2A_CHICK DNA topoisomerase 2-alpha OS=Gall...11730     1073     49     65GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:AgBase.::GO:0005654; C:nucleoplasm; ISS:AgBase.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:AgBase.::GO:0008144; F:drug binding; ISS:AgBase.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.
GO:0030263; P:apoptotic chromosome condensation; ISS:AgBase.::GO:0006266; P:DNA ligation; ISS:AgBase.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; ISS:AgBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:AgBase.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
19Q01320    1528   TOP2A_MOUSE DNA topoisomerase 2-alpha OS=Mus ...11710     1073     49     65GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005730; C:nucleolus; IDA:MGI.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:MGI.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.
GO:0030261; P:chromosome condensation; IMP:MGI.::GO:0006265; P:DNA topological change; IDA:MGI.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0040016; P:embryonic cleavage; IMP:MGI.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
20P41516    1526   TOP2A_RAT DNA topoisomerase 2-alpha OS=Rattus...11720     1063     49     65GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:RGD.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; IDA:RGD.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:RGD.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0043566; F:structure-specific DNA binding; IDA:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0006265; P:DNA topological change; IDA:RGD.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0071107; P:response to parathyroid hormone stimulus; IEP:RGD.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
21Q23670    1520   TOP2_CAEEL Probable DNA topoisomerase 2 OS=Ca...11870     1045     47     65GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.
GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
22Q55BP5    1521   TOP2_DICDI Probable DNA topoisomerase 2 OS=Di...12670     1018     44     62GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:dictyBase.
GO:0006265; P:DNA topological change; ISS:dictyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
23P90520    1284   TOP2M_DICDI DNA topoisomerase 2, mitochondria...12220     900     42     62GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:dictyBase.
GO:0006265; P:DNA topological change; IC:dictyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
24Q5UQE6    1263   TOP2_MIMIV DNA topoisomerase 2 OS=Acanthamoeb...1430.000000000000006     84.3     36     57GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
25P34534    1170   TOP2M_CAEEL Putative DNA topoisomerase 2, mit...11920     793     40     57GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.
GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
26P41001    1398   TOP2_PLAFK DNA topoisomerase 2 OS=Plasmodium ...9210     737     45     63GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
27O61078    1236   TOP2_LEICH DNA topoisomerase 2 OS=Leishmania ...11930     579     31     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
28P12531    1221   TOP2_TRYBB DNA topoisomerase 2 OS=Trypanosoma...11980     579     32     51GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
29P30190    1232   TOP2_TRYCR DNA topoisomerase 2 OS=Trypanosoma...10850     579     33     53GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
30P27570    1239   TOP2_CRIFA DNA topoisomerase 2 OS=Crithidia f...10862e-180     577     33     53GO:0005694; C:chromosome; IEA:InterPro.::GO:0020023; C:kinetoplast; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
31Q9QSK1    1132   TOP2_IIV6 DNA topoisomerase 2 OS=Invertebrate...11133e-175     560     35     52GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 287 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::