UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL082W

Length:

873

Number of sequences:

5887

Description:

YNL082W PMS1 SGDID:S000005026, Chr XIV from 473391-476012, Genome Release 64-1-1, Verified ORF, "ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P14242	873	PMS1_YEAST DNA mismatch repair protein PMS1 O...	873	0	1804	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0032389; C:MutLalpha complex; IPI:SGD.
									GO:0005524; F:ATP binding; IMP:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
2	P54278	862	PMS2_HUMAN Mismatch repair endonuclease PMS2 ...	227	5e-56	211	47	65	GO:0032389; C:MutLalpha complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0032138; F:single base insertion or deletion binding; IDA:HGNC.
									GO:0006298; P:mismatch repair; IDA:HGNC.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
3	P54280	794	PMS1_SCHPO DNA mismatch repair protein pms1 O...	208	3e-53	202	46	67	GO:0032389; C:MutLalpha complex; ISS:RefGenome.::GO:0000228; C:nuclear chromosome; ISS:PomBase.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0030983; F:mismatched DNA binding; NAS:PomBase.
									GO:0043570; P:maintenance of DNA repeat elements; IMP:PomBase.::GO:0006298; P:mismatch repair; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.
4	P54279	859	PMS2_MOUSE Mismatch repair endonuclease PMS2 ...	252	4e-59	220	44	63	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
5	Q54QA0	1022	PMS1_DICDI Mismatch repair endonuclease pms1 ...	207	5e-42	169	45	62	GO:0032389; C:MutLalpha complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0016887; F:ATPase activity; ISS:dictyBase.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; ISS:dictyBase.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
6	P54277	932	PMS1_HUMAN PMS1 protein homolog 1 OS=Homo sap...	367	4e-41	167	30	51	GO:0032389; C:MutLalpha complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
7	B2GB18	647	MUTL_LACF3 DNA mismatch repair protein mutL O...	200	0.000000001	65.5	26	43
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
8	Q1WT16	659	MUTL_LACS1 DNA mismatch repair protein mutL O...	245	0.0000000005	67	25	42
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
9	A4D2B8	440	PM2P1_HUMAN Putative postmeiotic segregation ...	166	9e-39	154	48	65	GO:0032389; C:MutLalpha complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
10	O95744	297	PM2P2_HUMAN Putative postmeiotic segregation ...	169	2e-37	147	46	65	GO:0032389; C:MutLalpha complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
11	A8FDH4	633	MUTL_BACP2 DNA mismatch repair protein mutL O...	188	0.00004	50.8	27	46
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
12	Q035Z3	651	MUTL_LACC3 DNA mismatch repair protein mutL O...	168	0.0000000005	66.6	30	48
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
13	Q8F6X4	593	MUTL_LEPIN DNA mismatch repair protein mutL O...	43	0.004	44.3	42	60	GO:0032300; C:mismatch repair complex; ISS:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; ISS:RefGenome.::GO:0030983; F:mismatched DNA binding; ISS:RefGenome.
									GO:0006298; P:mismatch repair; ISS:RefGenome.
14	Q72PF7	593	MUTL_LEPIC DNA mismatch repair protein mutL O...	43	0.004	44.3	42	60
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
15	Q9JYT2	658	MUTL_NEIMB DNA mismatch repair protein mutL O...	181	0.02	42.4	24	42
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
16	A3CWX7	585	MUTL_METMJ DNA mismatch repair protein mutL O...	196	0.0000000000001	78.2	29	44
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
17	Q9JTS2	658	MUTL_NEIMA DNA mismatch repair protein mutL O...	181	0.047	41.2	23	42
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
18	Q65JE1	636	MUTL_BACLD DNA mismatch repair protein mutL O...	188	0.000007	53.5	28	44
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
19	Q5F8M6	658	MUTL_NEIG1 DNA mismatch repair protein mutL O...	178	0.047	41.2	23	42
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
20	B4RLX4	658	MUTL_NEIG2 DNA mismatch repair protein mutL O...	178	0.046	41.2	23	42
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
21	B3W9W3	651	MUTL_LACCB DNA mismatch repair protein mutL O...	168	0.0000000006	66.6	30	48
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
22	A1KUP6	658	MUTL_NEIMF DNA mismatch repair protein mutL O...	177	0.037	41.2	23	37
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
23	A9M0G1	658	MUTL_NEIM0 DNA mismatch repair protein mutL O...	357	4e-36	149	29	48
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
24	Q5WFY4	654	MUTL_BACSK DNA mismatch repair protein mutL O...	196	0.000000000005	73.2	27	47
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
25	B2G6E6	668	MUTL_LACRJ DNA mismatch repair protein mutL O...	198	0.0000000009	65.9	25	43
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
26	A5VIX0	668	MUTL_LACRD DNA mismatch repair protein mutL O...	198	0.0000000009	65.9	25	43
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
27	P40692	756	MLH1_HUMAN DNA mismatch repair protein Mlh1 O...	346	6e-36	149	30	51	GO:0005712; C:chiasma; IBA:RefGenome.::GO:0032389; C:MutLalpha complex; IBA:RefGenome.::GO:0032390; C:MutLbeta complex; IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0016887; F:ATPase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006298; P:mismatch repair; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
28	A0Q0M7	645	MUTL_CLONN DNA mismatch repair protein mutL O...	192	0.000000000001	75.5	27	53
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
29	A3CR14	647	MUTL_STRSV DNA mismatch repair protein mutL O...	196	0.000000004	63.9	27	46
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
30	B7GIA3	608	MUTL_ANOFW DNA mismatch repair protein mutL O...	186	0.0001	49.7	24	46
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
31	A4IMI1	645	MUTL_GEOTN DNA mismatch repair protein mutL O...	186	0.002	45.8	24	44
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.

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