Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL079C
Length:
199
Number of sequences:
5887
Description:
YNL079C TPM1 SGDID:S000005023, Chr XIV from 479165-478566, Genome Release 64-1-1, reverse complement, Verified ORF, "Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q5JGH7    642   SYR_PYRKO Arginine--tRNA ligase OS=(Thermococ...1604.3     32     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004814; F:arginine-tRNA ligase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
92O43166    1804   SI1L1_HUMAN Signal-induced proliferation-asso...954.3     32     26     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0032861; P:activation of Rap GTPase activity; ISS:UniProtKB.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
93P07951    284   TPM2_HUMAN Tropomyosin beta chain OS=Homo sap...2074.4     31.6     26     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005862; C:muscle thin filament tropomyosin; TAS:ProtInc.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0043462; P:regulation of ATPase activity; IDA:UniProtKB.
94Q8LE98    344   ICR1_ARATH Interactor of constitutive active ...1034.5     31.6     33     51GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0090404; C:pollen tube tip; IDA:TAIR.
GO:2000012; P:regulation of auxin polar transport; IMP:TAIR.
95Q9UB83    284   TPM_PERAM Tropomyosin OS=Periplaneta american...904.5     31.6     33     49
96O35412    1822   SI1L1_RAT Signal-induced proliferation-associ...954.9     31.6     26     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; TAS:RGD.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0032861; P:activation of Rap GTPase activity; IDA:UniProtKB.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IDA:UniProtKB.::GO:0048167; P:regulation of synaptic plasticity; IDA:UniProtKB.
97P11047    1609   LAMC1_HUMAN Laminin subunit gamma-1 OS=Homo s...1865.1     31.6     22     41GO:0005615; C:extracellular space; NAS:UniProtKB.::GO:0005606; C:laminin-1 complex; NAS:UniProtKB.::GO:0043259; C:laminin-10 complex; TAS:BHF-UCL.::GO:0043260; C:laminin-11 complex; TAS:BHF-UCL.
GO:0005201; F:extracellular matrix structural constituent; IMP:HGNC.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016477; P:cell migration; IMP:HGNC.::GO:0007492; P:endoderm development; TAS:ProtInc.::GO:0022617; P:extracellular matrix disassembly; IMP:HGNC.::GO:0031581; P:hemidesmosome assembly; IMP:HGNC.::GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.::GO:0006461; P:protein complex assembly; IDA:HGNC.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
98Q61043    2035   NIN_MOUSE Ninein OS=Mus musculus (Mouse). GN=...1956     31.6     28     49GO:0005814; C:centriole; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019900; F:kinase binding; IPI:MGI.
GO:0090222; P:centrosome-templated microtubule nucleation; IMP:MGI.::GO:0034454; P:microtubule anchoring at centrosome; IMP:MGI.
99Q24JY3    197   SPC24_BOVIN Kinetochore protein Spc24 OS=Bos ...966.2     30.8     30     54GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0031262; C:Ndc80 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
100Q96CN4    794   EVI5L_HUMAN EVI5-like protein OS=Homo sapiens...1636.3     31.2     29     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
101Q96SN8    1893   CK5P2_HUMAN CDK5 regulatory subunit-associate...567.4     31.2     39     55GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0042808; F:neuronal Cdc2-like kinase binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0051297; P:centrosome organization; IMP:UniProtKB.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000132; P:establishment of mitotic spindle orientation; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; IDA:UniProtKB.
102Q8BHS8    665   SYBU_MOUSE Syntabulin OS=Mus musculus (Mouse)...827.5     31.2     26     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
103Q19UN5    1893   CK5P2_PANTR CDK5 regulatory subunit-associate...567.6     31.2     39     55GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0000132; P:establishment of mitotic spindle orientation; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; ISS:UniProtKB.::GO:0022008; P:neurogenesis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.
104A0JM56    1502   LRRC9_XENTR Leucine-rich repeat-containing pr...1517.6     31.2     26     53
105Q3ZCL3    309   NMI_BOVIN N-myc-interactor OS=Bos taurus (Bov...907.8     30.8     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
106Q498L9    1387   KI15B_XENLA Kinesin-like protein KIF15-B OS=X...1138.3     30.8     27     54GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0008574; F:plus-end-directed microtubule motor activity; IDA:UniProtKB.
GO:0051299; P:centrosome separation; IMP:UniProtKB.::GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
107Q5XGL1    274   CENPK_XENLA Centromere protein K OS=Xenopus l...718.8     30.4     32     55GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
108Q96PV0    1343   SYGP1_HUMAN Ras GTPase-activating protein Syn...878.8     30.8     28     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.
109Q3ZCC3    542   TRAF6_BOVIN TNF receptor-associated factor 6 ...799.3     30.8     27     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
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