rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | O16850 | 541 | FOXO_CAEEL Forkhead box protein O OS=Caenorha... | 86 | 0.000000002 | 64.3 | 42 | 60 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060537; P:muscle tissue development; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0002821; P:positive regulation of adaptive immune response; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IEP:UniProtKB.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; IMP:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 212 | Q3BJS0 | 295 | FOXN5_XENLA Forkhead box protein N5 OS=Xenopu... | 61 | 0.000000005 | 62 | 34 | 69 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 213 | P98177 | 505 | FOXO4_HUMAN Forkhead box protein O4 OS=Homo s... | 64 | 0.000000007 | 62.8 | 45 | 67 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 214 | Q9WVH3 | 505 | FOXO4_MOUSE Forkhead box protein O4 OS=Mus mu... | 64 | 0.000000008 | 62.8 | 45 | 67 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000080; P:G1 phase of mitotic cell cycle; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:MGI.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 215 | Q3UM89 | 302 | FOXR2_MOUSE Forkhead box protein R2 OS=Mus mu... | 83 | 0.000000009 | 61.2 | 33 | 58 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 216 | Q28H65 | 293 | FOXN5_XENTR Forkhead box protein N5 OS=Xenopu... | 61 | 0.00000001 | 60.8 | 34 | 69 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 217 | Q66JJ0 | 626 | FOXO1_XENTR Forkhead box protein O1 OS=Xenopu... | 63 | 0.00000006 | 60.1 | 44 | 68 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 218 | Q6EUW2 | 631 | FOXO1_XENLA Forkhead box protein O1 OS=Xenopu... | 63 | 0.00000007 | 60.1 | 44 | 68 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 219 | O43524 | 673 | FOXO3_HUMAN Forkhead box protein O3 OS=Homo s... | 106 | 0.0000001 | 59.3 | 37 | 56 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0001547; P:antral ovarian follicle growth; IBA:RefGenome.::GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0006917; P:induction of apoptosis; IBA:RefGenome.::GO:0001544; P:initiation of primordial ovarian follicle growth; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0001556; P:oocyte maturation; IBA:RefGenome.::GO:0001542; P:ovulation from ovarian follicle; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006417; P:regulation of translation; IDA:UniProtKB.::GO:0009888; P:tissue development; IBA:RefGenome. | 220 | B4JSC2 | 630 | FOXO_DROGR Forkhead box protein O OS=Drosophi... | 110 | 0.0000001 | 58.9 | 35 | 57 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 221 | Q3UTB7 | 268 | FOXR1_MOUSE Forkhead box protein R1 OS=Mus mu... | 89 | 0.0000001 | 57.4 | 33 | 55 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 222 | Q9WVH4 | 672 | FOXO3_MOUSE Forkhead box protein O3 OS=Mus mu... | 113 | 0.0000001 | 58.9 | 36 | 54 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0001547; P:antral ovarian follicle growth; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0001544; P:initiation of primordial ovarian follicle growth; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0001556; P:oocyte maturation; IMP:MGI.::GO:0001542; P:ovulation from ovarian follicle; IMP:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045648; P:positive regulation of erythrocyte differentiation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006417; P:regulation of translation; ISS:UniProtKB.::GO:0009888; P:tissue development; IBA:RefGenome. | 223 | Q6PIV2 | 292 | FOXR1_HUMAN Forkhead box protein R1 OS=Homo s... | 94 | 0.0000003 | 56.6 | 32 | 54 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 224 | Q12778 | 655 | FOXO1_HUMAN Forkhead box protein O1 OS=Homo s... | 63 | 0.0000005 | 57 | 43 | 68 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 225 | Q9R1E0 | 652 | FOXO1_MOUSE Forkhead box protein O1 OS=Mus mu... | 63 | 0.0000005 | 57 | 43 | 68 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 226 | Q810W5 | 653 | FOXO1_SPETR Forkhead box protein O1 OS=(Ictid... | 63 | 0.0000005 | 57 | 43 | 68 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 227 | B4G4S8 | 629 | FOXO_DROPE Forkhead box protein O OS=Drosophi... | 113 | 0.0000007 | 56.6 | 35 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 228 | B4MB78 | 609 | FOXO_DROVI Forkhead box protein O OS=Drosophi... | 70 | 0.0000008 | 56.2 | 40 | 64 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 229 | B4KBF6 | 563 | FOXO_DROMO Forkhead box protein O OS=Drosophi... | 70 | 0.000001 | 55.8 | 40 | 64 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 230 | Q6EUW1 | 657 | FOXO3_XENLA Forkhead box protein O3 OS=Xenopu... | 86 | 0.000001 | 55.8 | 38 | 58 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 231 | B4HF64 | 609 | FOXO_DROSE Forkhead box protein O OS=Drosophi... | 63 | 0.000001 | 55.8 | 41 | 67 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 232 | Q298W7 | 644 | FOXO_DROPS Forkhead box protein O OS=Drosophi... | 112 | 0.000001 | 55.8 | 33 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 233 | B3LYS5 | 600 | FOXO_DROAN Forkhead box protein O OS=Drosophi... | 70 | 0.000001 | 55.5 | 40 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 234 | A8MYZ6 | 492 | FOXO6_HUMAN Forkhead box protein O6 OS=Homo s... | 63 | 0.000001 | 55.5 | 41 | 67 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 235 | Q95V55 | 613 | FOXO_DROME Forkhead box protein O OS=Drosophi... | 70 | 0.000001 | 55.5 | 40 | 63 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; IMP:FlyBase.::GO:0009267; P:cellular response to starvation; IMP:FlyBase.::GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0005977; P:glycogen metabolic process; IMP:FlyBase.::GO:0008286; P:insulin receptor signaling pathway; IGI:FlyBase.::GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:FlyBase.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:FlyBase.::GO:0040027; P:negative regulation of vulval development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0019216; P:regulation of lipid metabolic process; IMP:UniProtKB.::GO:0016241; P:regulation of macroautophagy; IMP:FlyBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009617; P:response to bacterium; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0009888; P:tissue development; IBA:RefGenome. | 236 | B3P0K6 | 615 | FOXO_DROER Forkhead box protein O OS=Drosophi... | 63 | 0.000001 | 55.5 | 41 | 67 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 237 | B4PTD3 | 628 | FOXO_DROYA Forkhead box protein O OS=Drosophi... | 63 | 0.000002 | 55.5 | 41 | 67 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 238 | Q70KY4 | 559 | FOXO6_MOUSE Forkhead box protein O6 OS=Mus mu... | 63 | 0.000002 | 55.5 | 41 | 67 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 239 | B4NFR1 | 628 | FOXO_DROWI Forkhead box protein O OS=Drosophi... | 70 | 0.000002 | 55.5 | 40 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 240 | Q19802 | 461 | FKH5_CAEEL Putative forkhead-related transcri... | 64 | 0.00002 | 51.6 | 38 | 61 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 241 | Q6PJQ5 | 311 | FOXR2_HUMAN Forkhead box protein R2 OS=Homo s... | 119 | 0.00007 | 49.3 | 22 | 48 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. |