Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL053W
Length:
489
Number of sequences:
5887
Description:
YNL053W MSG5 SGDID:S000004998, Chr XIV from 529942-531411, Genome Release 64-1-1, Verified ORF, "Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9M8K7    167   DUS1B_ARATH Dual specificity protein phosphat...740.000006     50.1     32     54GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.::GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.::GO:0010193; P:response to ozone; IMP:TAIR.
92P0C593    212   DUPD1_MONDO Dual specificity phosphatase DUPD...570.000006     50.4     47     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
93P0C597    214   DUPD1_CHICK Dual specificity phosphatase DUPD...1390.000007     50.4     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
94P0C596    222   DUPD1_PIG Dual specificity phosphatase DUPD1 ...700.000007     50.4     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
95Q6B8I1    188   MDSP_HUMAN Dual specificity protein phosphata...640.000007     50.1     44     64GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
96P0C592    220   DUPD1_HORSE Dual specificity phosphatase DUPD...680.000008     50.4     46     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
97Q6B8I0    188   MDSP_MOUSE Dual specificity protein phosphata...570.000008     50.1     46     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI.
98Q75QN6    929   PHS1_ARATH Dual specificity protein phosphata...590.000008     52.4     42     61GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043622; P:cortical microtubule organization; IMP:TAIR.::GO:0010468; P:regulation of gene expression; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
99P0C591    219   DUPD1_BOVIN Dual specificity phosphatase DUPD...810.000009     50.1     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
100Q8BK84    215   DUPD1_MOUSE Dual specificity phosphatase DUPD...730.00001     49.7     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
101Q02256    364   PVH1_YEAST Tyrosine-protein phosphatase YVH1 ...560.00001     50.8     43     59GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0019933; P:cAMP-mediated signaling; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
102Q55CS7    834   MPL1_DICDI MAP kinase phosphatase with leucin...920.00002     51.2     32     54GO:0005576; C:extracellular region; IC:dictyBase.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IMP:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.
103P0C595    215   DUPD1_RAT Dual specificity phosphatase DUPD1 ...650.00002     49.3     45     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
104Q55CS8    695   MPL2_DICDI MAP kinase phosphatase with leucin...920.00003     50.4     34     53
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
105P0C594    220   DUPD1_PANTR Dual specificity phosphatase DUPD...700.00004     48.5     43     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
106A4IHU7    209   DUPD1_XENTR Dual specificity phosphatase DUPD...1650.00005     48.1     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
107Q68J44    220   DUPD1_HUMAN Dual specificity phosphatase DUPD...570.00005     48.1     47     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
108Q8BTR5    163   DUS28_MOUSE Dual specificity phosphatase 28 O...730.00007     46.6     34     53
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
109Q550K8    2454   Y7071_DICDI Probable serine/threonine-protein...1140.00008     49.3     30     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
110Q9UII6    198   DUS13_HUMAN Dual specificity protein phosphat...680.0002     46.2     40     63
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0007126; P:meiosis; TAS:ProtInc.::GO:0007283; P:spermatogenesis; TAS:ProtInc.
111Q9D7X3    185   DUS3_MOUSE Dual specificity protein phosphata...680.0002     45.8     35     60GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI.
GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome.
112O10273    160   PTP2_NPVOP Tyrosine-protein phosphatase 2 OS=...400.0002     45.1     48     68
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
113Q8WTR2    217   DUS19_HUMAN Dual specificity protein phosphat...630.0002     45.8     33     54GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0008579; F:JUN kinase phosphatase activity; IBA:RefGenome.::GO:0005078; F:MAP-kinase scaffold activity; ISS:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; ISS:BHF-UCL.::GO:0030295; F:protein kinase activator activity; ISS:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:BHF-UCL.
114Q4KL92    209   DUPD1_XENLA Dual specificity phosphatase DUPD...1650.0004     45.1     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
115P0C5A2    211   DUPD1_CALMI Dual specificity phosphatase DUPD...530.001     44.3     43     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
116Q5VZP5    1158   DUS27_HUMAN Inactive dual specificity phospha...850.001     45.4     32     54
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
117Q29RA3    189   DUPD1_DANRE Dual specificity phosphatase DUPD...620.001     43.9     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
118Q5RD73    185   DUS3_PONAB Dual specificity protein phosphata...790.001     43.5     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
119P51452    185   DUS3_HUMAN Dual specificity protein phosphata...790.001     43.5     32     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
120Q84JU4    257   IBR5_ARATH Protein-tyrosine-phosphatase IBR5 ...1460.002     43.5     25     43GO:0005634; C:nucleus; IDA:TAIR.
GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.
121Q54R42    230   DUSP2_DICDI Probable dual specificity protein...520.002     43.1     40     62
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
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