Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL053W
Length:
489
Number of sequences:
5887
Description:
YNL053W MSG5 SGDID:S000004998, Chr XIV from 529942-531411, Genome Release 64-1-1, Verified ORF, "Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q64623    367   DUS1_RAT Dual specificity protein phosphatase...1410.0000000002     65.9     30     50GO:0005654; C:nucleoplasm; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; IDA:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0009416; P:response to light stimulus; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
32Q16829    419   DUS7_HUMAN Dual specificity protein phosphata...1200.0000000003     65.5     33     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
33Q9D700    211   DUS26_MOUSE Dual specificity protein phosphat...650.0000000003     63.2     51     69GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
34Q13115    394   DUS4_HUMAN Dual specificity protein phosphata...1970.0000000004     65.1     27     45GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; TAS:ProtInc.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
35Q9BV47    211   DUS26_HUMAN Dual specificity protein phosphat...650.0000000004     62.8     52     69GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
36Q5R6H6    211   DUS26_PONAB Dual specificity protein phosphat...650.0000000005     62.8     52     69GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
37Q9JLY7    198   DUS14_MOUSE Dual specificity protein phosphat...730.0000000005     62.4     41     62GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
38Q62767    395   DUS4_RAT Dual specificity protein phosphatase...1980.0000000006     64.7     27     45GO:0005654; C:nucleoplasm; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; IDA:RGD.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0010033; P:response to organic substance; IEP:RGD.
39Q8BFV3    398   DUS4_MOUSE Dual specificity protein phosphata...1980.0000000007     64.3     27     45GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.
40Q17QJ3    211   DUS26_BOVIN Dual specificity protein phosphat...650.0000000007     62.4     51     69GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
41Q16690    384   DUS5_HUMAN Dual specificity protein phosphata...970.0000000008     64.3     30     57GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001706; P:endoderm formation; IBA:RefGenome.
42Q8VE01    188   DUS18_MOUSE Dual specificity protein phosphat...1270.0000000009     61.6     32     49GO:0031314; C:extrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0031304; C:intrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.::GO:0046677; P:response to antibiotic; ISS:MGI.
43Q9VVW5    411   DUSK3_DROME Dual specificity protein phosphat...1510.000000001     63.9     30     50GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0042127; P:regulation of cell proliferation; IGI:FlyBase.
44Q5BIP9    188   DUS18_BOVIN Dual specificity protein phosphat...1290.000000001     61.2     33     51GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
45Q5FVI9    211   DUS26_RAT Dual specificity protein phosphatas...650.000000001     61.6     51     68GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
46O54838    384   DUS5_RAT Dual specificity protein phosphatase...1470.000000002     63.2     29     47GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.
47Q9H596    190   DUS21_HUMAN Dual specificity protein phosphat...1210.000000002     60.8     32     51GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
48Q8NEJ0    188   DUS18_HUMAN Dual specificity protein phosphat...1330.000000002     60.8     32     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
49Q5R8X2    188   DUS18_PONAB Dual specificity protein phosphat...1330.000000003     60.1     32     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
50Q17QM8    198   DUS14_BOVIN Dual specificity protein phosphat...730.000000004     60.1     40     60
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
51O95147    198   DUS14_HUMAN Dual specificity protein phosphat...730.000000004     60.1     40     60
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
52Q9PW71    375   DUS4_CHICK Dual specificity protein phosphata...1570.000000007     61.2     29     47GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.
53Q05923    314   DUS2_HUMAN Dual specificity protein phosphata...1460.000000007     60.8     29     49GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; TAS:ProtInc.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
54Q4V7N3    223   STYXA_XENLA Serine/threonine/tyrosine-interac...1080.000000008     59.3     31     53
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
55Q5U593    223   STYXB_XENLA Serine/threonine/tyrosine-interac...1080.000000008     59.3     31     53
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
56Q6AXW7    204   DUS18_RAT Dual specificity protein phosphatas...1340.000000009     58.9     32     46GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
57Q5XHB2    209   DUS22_XENTR Dual specificity protein phosphat...670.00000001     58.9     40     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
58Q60969    223   STYX_MOUSE Serine/threonine/tyrosine-interact...1260.00000001     58.9     29     46
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
59Q9C5S1    784   MKP1_ARATH Protein-tyrosine-phosphatase MKP1 ...1110.00000001     61.2     33     42GO:0005829; C:cytosol; IDA:TAIR.
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:TAIR.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0010224; P:response to UV-B; IMP:TAIR.::GO:0010225; P:response to UV-C; IMP:TAIR.
60Q05922    318   DUS2_MOUSE Dual specificity protein phosphata...1460.00000002     59.7     29     49GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
61Q8WUJ0    223   STYX_HUMAN Serine/threonine/tyrosine-interact...760.00000002     58.5     34     55GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0007283; P:spermatogenesis; IBA:RefGenome.
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