Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL053W
Length:
489
Number of sequences:
5887
Description:
YNL053W MSG5 SGDID:S000004998, Chr XIV from 529942-531411, Genome Release 64-1-1, Verified ORF, "Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38590    489   MSG5_YEAST Tyrosine-protein phosphatase MSG5 ...4890     998     100     100GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
2P40479    209   SDP1_YEAST Dual-specificity protein phosphata...1515e-47     167     52     72GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0033550; F:MAP kinase tyrosine phosphatase activity; IDA:SGD.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
3P43078    597   PTPX_CANAW Probable tyrosine-protein phosphat...1572e-33     136     45     61
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
4O13453    278   PMP1_SCHPO Tyrosine-protein phosphatase pmp1 ...1645e-31     125     39     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; ISS:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; NAS:PomBase.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
5O55737    142   123R_IIV6 Putative tyrosine phosphatase 123R ...1230.000000000000005     76.6     38     59
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
6Q76I79    1042   SSH1_MOUSE Protein phosphatase Slingshot homo...1490.0000000000001     77.4     36     51GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
7Q8WYL5    1049   SSH1_HUMAN Protein phosphatase Slingshot homo...1490.0000000000001     77.4     36     51GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0000902; P:cell morphogenesis; IMP:UniProtKB.::GO:0071318; P:cellular response to ATP; IDA:MGI.::GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0032268; P:regulation of cellular protein metabolic process; IDA:MGI.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
8Q8K330    649   SSH3_MOUSE Protein phosphatase Slingshot homo...1420.0000000000005     75.1     32     53GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
9Q5XIS1    652   SSH3_RAT Protein phosphatase Slingshot homolo...1400.000000000001     73.6     31     54GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
10Q0IID7    482   DUS10_BOVIN Dual specificity protein phosphat...1370.000000000004     72     32     53GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
11Q9ESS0    483   DUS10_MOUSE Dual specificity protein phosphat...1370.000000000004     71.6     32     53GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046329; P:negative regulation of JNK cascade; IMP:MGI.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:MGI.::GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IMP:MGI.::GO:0002819; P:regulation of adaptive immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
12Q9Y6W6    482   DUS10_HUMAN Dual specificity protein phosphat...1370.000000000004     71.6     32     53GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
13Q76I76    1423   SSH2_HUMAN Protein phosphatase Slingshot homo...2160.000000000005     72.4     29     45GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
14Q5SW75    1423   SSH2_MOUSE Protein phosphatase Slingshot homo...2160.000000000006     72     29     45GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
15O09112    663   DUS8_MOUSE Dual specificity protein phosphata...1380.000000000006     71.6     31     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
16Q13202    625   DUS8_HUMAN Dual specificity protein phosphata...1380.000000000007     71.2     31     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
17Q10038    657   VHP1_CAEEL Tyrosine-protein phosphatase vhp-1...1500.000000000008     71.2     29     49GO:0005737; C:cytoplasm; ISS:WormBase.::GO:0005634; C:nucleus; ISS:WormBase.
GO:0008579; F:JUN kinase phosphatase activity; IDA:WormBase.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:WormBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0006952; P:defense response; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0046329; P:negative regulation of JNK cascade; IDA:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0046688; P:response to copper ion; IGI:WormBase.
18Q9BY84    665   DUS16_HUMAN Dual specificity protein phosphat...1580.000000000008     71.2     32     53GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0045204; P:MAPK export from nucleus; TAS:UniProtKB.::GO:0045209; P:MAPK phosphatase export from nucleus, leptomycin B sensitive; TAS:UniProtKB.
19Q99956    384   DUS9_HUMAN Dual specificity protein phosphata...1490.00000000002     69.3     36     50GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005783; C:endoplasmic reticulum; IDA:HPA.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; TAS:ProtInc.
20P28562    367   DUS1_HUMAN Dual specificity protein phosphata...1550.00000000002     69.3     30     51GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0001706; P:endoderm formation; IBA:RefGenome.
21Q2KJ36    381   DUS6_BOVIN Dual specificity protein phosphata...1240.00000000002     68.9     33     52GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.
22Q16828    381   DUS6_HUMAN Dual specificity protein phosphata...1240.00000000002     68.9     33     52GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
23Q9DBB1    381   DUS6_MOUSE Dual specificity protein phosphata...1240.00000000002     68.9     33     52GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IMP:MGI.
24Q64346    381   DUS6_RAT Dual specificity protein phosphatase...1240.00000000003     68.6     33     52GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEP:RGD.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
25Q8TE77    659   SSH3_HUMAN Protein phosphatase Slingshot homo...1420.00000000003     69.3     32     53GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
26Q63340    280   DUS7_RAT Dual specificity protein phosphatase...1320.00000000004     67     33     50GO:0005829; C:cytosol; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
27Q6NN85    1045   SSH_DROME Protein phosphatase Slingshot OS=Dr...1610.00000000004     69.3     31     48GO:0045177; C:apical part of cell; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; NAS:FlyBase.
GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0048749; P:compound eye development; IGI:FlyBase.::GO:0040023; P:establishment of nucleus localization; IMP:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IMP:FlyBase.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.
28Q6IVY4    691   SSH_XENLA Protein phosphatase Slingshot homol...1390.0000000001     67.4     35     50GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
29Q91Z46    422   DUS7_MOUSE Dual specificity protein phosphata...1320.0000000001     66.6     33     50GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
30P28563    367   DUS1_MOUSE Dual specificity protein phosphata...1410.0000000002     66.2     30     50GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0001706; P:endoderm formation; IBA:RefGenome.
31Q64623    367   DUS1_RAT Dual specificity protein phosphatase...1410.0000000002     65.9     30     50GO:0005654; C:nucleoplasm; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; IDA:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0009416; P:response to light stimulus; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
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