Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL047C
Length:
656
Number of sequences:
5887
Description:
YNL047C SLM2 SGDID:S000004992, Chr XIV from 541881-539911, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53955    656   SLM2_YEAST Phosphatidylinositol 4,5-bisphosph...6560     1345     100     100GO:0005886; C:plasma membrane; IDA:SGD.
GO:0035091; F:phosphatidylinositol binding; TAS:SGD.
GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0016197; P:endosome transport; IGI:SGD.::GO:0001558; P:regulation of cell growth; IGI:SGD.::GO:0031929; P:TOR signaling cascade; IPI:SGD.
2P40485    686   SLM1_YEAST Phosphatidylinositol 4,5-bisphosph...5470     639     61     76GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0046625; F:sphingolipid binding; IDA:SGD.
GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0016197; P:endosome transport; IGI:SGD.::GO:0001558; P:regulation of cell growth; IGI:SGD.::GO:0031929; P:TOR signaling cascade; IPI:SGD.
3Q06108    1083   RGC1_YEAST Regulator of the glycerol channel ...3778e-56     209     35     56GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0090372; P:positive regulation of glycerol transport; IMP:SGD.
4P48361    1146   ASK10_YEAST Activator of SKN7 protein 10 OS=S...500.00002     51.6     36     64GO:0005737; C:cytoplasm; IDA:SGD.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:SGD.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0044257; P:cellular protein catabolic process; IMP:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0090372; P:positive regulation of glycerol transport; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
5O94447    498   YFED_SCHPO Uncharacterized PH domain-containi...3923e-22     104     23     44GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0005886; C:plasma membrane; ISS:PomBase.
GO:0035091; F:phosphatidylinositol binding; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; ISS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IC:PomBase.
6Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...1210.052     40.4     30     50GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
7Q5U2Z7    748   RHG24_RAT Rho GTPase-activating protein 24 OS...1110.056     40.4     26     46GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
8O08967    399   CYH3_MOUSE Cytohesin-3 OS=Mus musculus (Mouse...1240.073     39.7     28     51GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IPI:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0045785; P:positive regulation of cell adhesion; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
9Q8N264    748   RHG24_HUMAN Rho GTPase-activating protein 24 ...1110.077     40     25     48GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
10Q92636    917   FAN_HUMAN Protein FAN OS=Homo sapiens (Human)...1660.15     38.9     25     39GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
GO:0006672; P:ceramide metabolic process; TAS:ProtInc.
11O35242    920   FAN_MOUSE Protein FAN OS=Mus musculus (Mouse)...1720.15     38.9     26     38
GO:0005123; F:death receptor binding; TAS:MGI.
12Q9VZI3    708   UN112_DROME Unc-112-related protein OS=Drosop...1040.26     38.1     30     43GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0050839; F:cell adhesion molecule binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; ISS:UniProtKB.
13Q9ERS5    425   PKHA2_MOUSE Pleckstrin homology domain-contai...1060.28     37.7     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
14Q8C4V1    747   RHG24_MOUSE Rho GTPase-activating protein 24 ...1110.68     37     25     46GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
15Q06410    417   ATG17_YEAST Autophagy-related protein 17 OS=S...1010.7     36.6     29     48GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
GO:0032947; F:protein complex scaffold; IGI:SGD.::GO:0030295; F:protein kinase activator activity; IMP:SGD.
GO:0032147; P:activation of protein kinase activity; IMP:SGD.::GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.
16Q9UPN3    7388   MACF1_HUMAN Microtubule-actin cross-linking f...1090.7     37     26     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0051015; F:actin filament binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; NAS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB.
17Q76MY7    399   CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop...1240.84     36.2     26     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
18A7A1U4    417   ATG17_YEAS7 Autophagy-related protein 17 OS=S...561.1     35.8     38     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
19D3ZHV2    5430   MACF1_RAT Microtubule-actin cross-linking fac...952     35.4     24     52GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB.
20Q6IP76    485   AKT2B_XENLA RAC-beta serine/threonine-protein...1132.2     35     24     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
21Q82YY9    423   SYS2_ENTFA Serine--tRNA ligase 2 OS=Enterococ...663.4     34.3     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
22Q7SHX8    1125   EFR3_NEUCR Protein efr-3 OS=1257 / FGSC 987)....595.1     34.3     36     51
23P42331    645   RHG25_HUMAN Rho GTPase-activating protein 25 ...1225.2     33.9     24     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
24A8AYV0    425   SYS_STRGC Serine--tRNA ligase OS=V288). GN=se...665.5     33.9     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
25P39967    754   UBP9_YEAST Ubiquitin carboxyl-terminal hydrol...846.3     33.9     30     46GO:0005737; C:cytoplasm; IC:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
26Q6C0U8    990   CYM1_YARLI Mitochondrial presequence protease...656.4     33.9     28     58GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
27Q9HB21    404   PKHA1_HUMAN Pleckstrin homology domain-contai...1097.3     33.1     23     47GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0045184; P:establishment of protein localization; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:UniProtKB.::GO:0031529; P:ruffle organization; IDA:UniProtKB.
28Q54TT4    925   COG3_DICDI Conserved oligomeric Golgi complex...1207.7     33.5     28     45GO:0005801; C:cis-Golgi network; IEA:InterPro.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
29Q9QXZ0    7354   MACF1_MOUSE Microtubule-actin cross-linking f...959.1     33.5     23     54GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; IDA:MGI.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; IDA:MGI.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:MGI.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.::GO:0010632; P:regulation of epithelial cell migration; IMP:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:MGI.::GO:0042060; P:wound healing; IMP:UniProtKB.
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