rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53955 | 656 | SLM2_YEAST Phosphatidylinositol 4,5-bisphosph... | 656 | 0 | 1345 | 100 | 100 | GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; TAS:SGD. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0016197; P:endosome transport; IGI:SGD.::GO:0001558; P:regulation of cell growth; IGI:SGD.::GO:0031929; P:TOR signaling cascade; IPI:SGD. | 2 | P40485 | 686 | SLM1_YEAST Phosphatidylinositol 4,5-bisphosph... | 547 | 0 | 639 | 61 | 76 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0046625; F:sphingolipid binding; IDA:SGD. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0016197; P:endosome transport; IGI:SGD.::GO:0001558; P:regulation of cell growth; IGI:SGD.::GO:0031929; P:TOR signaling cascade; IPI:SGD. | 3 | Q06108 | 1083 | RGC1_YEAST Regulator of the glycerol channel ... | 377 | 8e-56 | 209 | 35 | 56 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0090372; P:positive regulation of glycerol transport; IMP:SGD. | 4 | P48361 | 1146 | ASK10_YEAST Activator of SKN7 protein 10 OS=S... | 50 | 0.00002 | 51.6 | 36 | 64 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:SGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0044257; P:cellular protein catabolic process; IMP:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0090372; P:positive regulation of glycerol transport; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD. | 5 | O94447 | 498 | YFED_SCHPO Uncharacterized PH domain-containi... | 392 | 3e-22 | 104 | 23 | 44 | GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0005886; C:plasma membrane; ISS:PomBase. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:PomBase. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; ISS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IC:PomBase. | 6 | Q54KA7 | 986 | SECG_DICDI Ankyrin repeat, PH and SEC7 domain... | 121 | 0.052 | 40.4 | 30 | 50 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 7 | Q5U2Z7 | 748 | RHG24_RAT Rho GTPase-activating protein 24 OS... | 111 | 0.056 | 40.4 | 26 | 46 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 8 | O08967 | 399 | CYH3_MOUSE Cytohesin-3 OS=Mus musculus (Mouse... | 124 | 0.073 | 39.7 | 28 | 51 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IPI:MGI. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0045785; P:positive regulation of cell adhesion; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 9 | Q8N264 | 748 | RHG24_HUMAN Rho GTPase-activating protein 24 ... | 111 | 0.077 | 40 | 25 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 10 | Q92636 | 917 | FAN_HUMAN Protein FAN OS=Homo sapiens (Human)... | 166 | 0.15 | 38.9 | 25 | 39 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005057; F:receptor signaling protein activity; TAS:ProtInc. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; TAS:ProtInc. | 11 | O35242 | 920 | FAN_MOUSE Protein FAN OS=Mus musculus (Mouse)... | 172 | 0.15 | 38.9 | 26 | 38 | | | | | | | | | | | GO:0005123; F:death receptor binding; TAS:MGI. | | | | | | | | | | | 12 | Q9VZI3 | 708 | UN112_DROME Unc-112-related protein OS=Drosop... | 104 | 0.26 | 38.1 | 30 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007160; P:cell-matrix adhesion; ISS:UniProtKB. | 13 | Q9ERS5 | 425 | PKHA2_MOUSE Pleckstrin homology domain-contai... | 106 | 0.28 | 37.7 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB. | | | | | | | | | | | 14 | Q8C4V1 | 747 | RHG24_MOUSE Rho GTPase-activating protein 24 ... | 111 | 0.68 | 37 | 25 | 46 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 15 | Q06410 | 417 | ATG17_YEAST Autophagy-related protein 17 OS=S... | 101 | 0.7 | 36.6 | 29 | 48 | GO:0000407; C:pre-autophagosomal structure; IDA:SGD. | | | | | | | | | | GO:0032947; F:protein complex scaffold; IGI:SGD.::GO:0030295; F:protein kinase activator activity; IMP:SGD. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; IMP:SGD.::GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD. | 16 | Q9UPN3 | 7388 | MACF1_HUMAN Microtubule-actin cross-linking f... | 109 | 0.7 | 37 | 26 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB. | 17 | Q76MY7 | 399 | CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop... | 124 | 0.84 | 36.2 | 26 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 18 | A7A1U4 | 417 | ATG17_YEAS7 Autophagy-related protein 17 OS=S... | 56 | 1.1 | 35.8 | 38 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 19 | D3ZHV2 | 5430 | MACF1_RAT Microtubule-actin cross-linking fac... | 95 | 2 | 35.4 | 24 | 52 | GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB. | 20 | Q6IP76 | 485 | AKT2B_XENLA RAC-beta serine/threonine-protein... | 113 | 2.2 | 35 | 24 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q82YY9 | 423 | SYS2_ENTFA Serine--tRNA ligase 2 OS=Enterococ... | 66 | 3.4 | 34.3 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro. | 22 | Q7SHX8 | 1125 | EFR3_NEUCR Protein efr-3 OS=1257 / FGSC 987).... | 59 | 5.1 | 34.3 | 36 | 51 | | | | | | | | | | | | | | | | | | | | | | 23 | P42331 | 645 | RHG25_HUMAN Rho GTPase-activating protein 25 ... | 122 | 5.2 | 33.9 | 24 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 24 | A8AYV0 | 425 | SYS_STRGC Serine--tRNA ligase OS=V288). GN=se... | 66 | 5.5 | 33.9 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro. | 25 | P39967 | 754 | UBP9_YEAST Ubiquitin carboxyl-terminal hydrol... | 84 | 6.3 | 33.9 | 30 | 46 | GO:0005737; C:cytoplasm; IC:SGD. | | | | | | | | | | GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD. | | | | | | | | | | GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 26 | Q6C0U8 | 990 | CYM1_YARLI Mitochondrial presequence protease... | 65 | 6.4 | 33.9 | 28 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 27 | Q9HB21 | 404 | PKHA1_HUMAN Pleckstrin homology domain-contai... | 109 | 7.3 | 33.1 | 23 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0045184; P:establishment of protein localization; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:UniProtKB.::GO:0031529; P:ruffle organization; IDA:UniProtKB. | 28 | Q54TT4 | 925 | COG3_DICDI Conserved oligomeric Golgi complex... | 120 | 7.7 | 33.5 | 28 | 45 | GO:0005801; C:cis-Golgi network; IEA:InterPro.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 29 | Q9QXZ0 | 7354 | MACF1_MOUSE Microtubule-actin cross-linking f... | 95 | 9.1 | 33.5 | 23 | 54 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; IDA:MGI. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:MGI.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.::GO:0010632; P:regulation of epithelial cell migration; IMP:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:MGI.::GO:0042060; P:wound healing; IMP:UniProtKB. |