rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q3SZH7 | 611 | LKHA4_BOVIN Leukotriene A-4 hydrolase OS=Bos ... | 613 | 7e-144 | 439 | 41 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 32 | P09960 | 611 | LKHA4_HUMAN Leukotriene A-4 hydrolase OS=Homo... | 615 | 5e-142 | 435 | 40 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; IDA:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IDA:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006954; P:inflammatory response; NAS:ProtInc.::GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.::GO:0043171; P:peptide catabolic process; IDA:UniProtKB.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 33 | Q6S9C8 | 611 | LKHA4_CHILA Leukotriene A-4 hydrolase OS=Chin... | 615 | 3e-141 | 433 | 40 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 34 | P24527 | 611 | LKHA4_MOUSE Leukotriene A-4 hydrolase OS=Mus ... | 615 | 2e-139 | 428 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 35 | P19602 | 611 | LKHA4_CAVPO Leukotriene A-4 hydrolase OS=Cavi... | 613 | 4e-138 | 424 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 36 | P52922 | 606 | LKHA4_DICDI Leukotriene A-4 hydrolase homolog... | 630 | 2e-136 | 420 | 40 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 37 | P30349 | 610 | LKHA4_RAT Leukotriene A-4 hydrolase OS=Rattus... | 615 | 9e-136 | 418 | 40 | 58 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IDA:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD.::GO:0060509; P:Type I pneumocyte differentiation; IEP:RGD. | 38 | Q8VCT3 | 650 | AMPB_MOUSE Aminopeptidase B OS=Mus musculus (... | 662 | 8e-101 | 328 | 33 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | O09175 | 650 | AMPB_RAT Aminopeptidase B OS=Rattus norvegicu... | 657 | 7e-98 | 320 | 33 | 52 | GO:0009897; C:external side of plasma membrane; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005794; C:Golgi apparatus; NAS:UniProtKB.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0050897; F:cobalt ion binding; IDA:RGD.::GO:0005507; F:copper ion binding; IDA:RGD.::GO:0070006; F:metalloaminopeptidase activity; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0016485; P:protein processing; NAS:UniProtKB.::GO:0006508; P:proteolysis; IC:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IEP:RGD. | 40 | Q9H4A4 | 650 | AMPB_HUMAN Aminopeptidase B OS=Homo sapiens (... | 651 | 3e-92 | 305 | 32 | 51 | | | | | | | | | | | GO:0004301; F:epoxide hydrolase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IC:UniProtKB. | 41 | Q9HAU8 | 494 | RNPL1_HUMAN Arginyl aminopeptidase-like 1 OS=... | 450 | 4e-47 | 178 | 27 | 44 | | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 42 | Q97VF1 | 784 | APE1_SULSO Probable aminopeptidase 1 OS=P2). ... | 445 | 3e-23 | 108 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | Q96ZT9 | 786 | APE1_SULTO Probable aminopeptidase 1 OS=Sulfo... | 431 | 4e-22 | 105 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 44 | P95928 | 785 | APE2_SULSO Leucyl aminopeptidase OS=P2). GN=a... | 424 | 8e-22 | 104 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 45 | Q10730 | 844 | AMPN_LACHE Aminopeptidase N OS=Lactobacillus ... | 472 | 1e-20 | 100 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 46 | P69527 | 816 | AMPO_RAT Aminopeptidase O OS=Rattus norvegicu... | 608 | 2e-20 | 99.8 | 22 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 47 | Q8N6M6 | 819 | AMPO_HUMAN Aminopeptidase O OS=Homo sapiens (... | 452 | 1e-19 | 97.4 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.::GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:UniProtKB. | 48 | Q8BXQ6 | 817 | AMPO_MOUSE Aminopeptidase O OS=Mus musculus (... | 426 | 2e-19 | 97.1 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 49 | Q978U3 | 783 | TRF2_THEVO Tricorn protease-interacting facto... | 468 | 2e-19 | 96.7 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 50 | Q9UIQ6 | 1025 | LCAP_HUMAN Leucyl-cystinyl aminopeptidase OS=... | 382 | 2e-19 | 96.7 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031905; C:early endosome lumen; TAS:Reactome.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; TAS:HGNC.::GO:0008237; F:metallopeptidase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc. | 51 | Q97AJ6 | 779 | TRF3_THEVO Tricorn protease-interacting facto... | 464 | 4e-19 | 95.5 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 52 | P15684 | 965 | AMPN_RAT Aminopeptidase N OS=Rattus norvegicu... | 343 | 1e-18 | 94 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031983; C:vesicle lumen; IDA:RGD.::GO:0012506; C:vesicle membrane; IDA:RGD. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006725; P:cellular aromatic compound metabolic process; IDA:RGD.::GO:0035814; P:negative regulation of renal sodium excretion; IMP:RGD.::GO:0006508; P:proteolysis; IDA:RGD. | 53 | Q8SRG3 | 864 | AMP12_ENCCU Probable M1 family aminopeptidase... | 351 | 3e-18 | 93.2 | 26 | 44 | | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 54 | P97629 | 1025 | LCAP_RAT Leucyl-cystinyl aminopeptidase OS=Ra... | 464 | 4e-18 | 92.8 | 25 | 42 | GO:0009986; C:cell surface; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0032593; C:insulin-responsive compartment; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0001595; F:angiotensin receptor activity; IMP:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0017046; F:peptide hormone binding; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010813; P:neuropeptide catabolic process; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0009725; P:response to hormone stimulus; IDA:RGD. | 55 | Q8C129 | 1025 | LCAP_MOUSE Leucyl-cystinyl aminopeptidase OS=... | 464 | 4e-18 | 92.8 | 24 | 42 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IMP:MGI.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 56 | Q8SQI6 | 864 | AMP11_ENCCU Probable M1 family aminopeptidase... | 351 | 5e-18 | 92.4 | 26 | 44 | | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 57 | P79171 | 967 | AMPN_FELCA Aminopeptidase N OS=Felis catus (C... | 366 | 9e-18 | 91.3 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 58 | P97449 | 966 | AMPN_MOUSE Aminopeptidase N OS=Mus musculus (... | 316 | 2e-17 | 90.5 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 59 | Q974N6 | 781 | APE2_SULTO Probable aminopeptidase 2 OS=Sulfo... | 378 | 2e-17 | 90.1 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 60 | P79098 | 965 | AMPN_BOVIN Aminopeptidase N OS=Bos taurus (Bo... | 321 | 3e-17 | 90.1 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 61 | Q95334 | 942 | AMPE_PIG Glutamyl aminopeptidase OS=Sus scrof... | 335 | 4e-17 | 89.4 | 27 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070006; F:metalloaminopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; ISS:UniProtKB. |