rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P28834 | 360 | IDH1_YEAST Isocitrate dehydrogenase [NAD] sub... | 360 | 0 | 736 | 100 | 100 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.::GO:0042645; C:mitochondrial nucleoid; IDA:SGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD. | 2 | O94229 | 361 | IDH1_KLULA Isocitrate dehydrogenase [NAD] sub... | 362 | 0 | 588 | 78 | 89 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 3 | O13302 | 388 | IDH1_AJECA Isocitrate dehydrogenase [NAD] sub... | 359 | 5e-157 | 453 | 59 | 79 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 4 | O13696 | 356 | IDH1_SCHPO Isocitrate dehydrogenase [NAD] sub... | 344 | 2e-144 | 420 | 58 | 77 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase. | 5 | P41565 | 393 | IDHG1_RAT Isocitrate dehydrogenase [NAD] subu... | 344 | 5e-116 | 349 | 50 | 69 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0045926; P:negative regulation of growth; IMP:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 6 | P41564 | 355 | IDH3G_MACFA Isocitrate dehydrogenase [NAD] su... | 344 | 1e-115 | 347 | 49 | 69 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 7 | Q58CP0 | 392 | IDH3G_BOVIN Isocitrate dehydrogenase [NAD] su... | 344 | 2e-115 | 347 | 50 | 69 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 8 | P51553 | 393 | IDH3G_HUMAN Isocitrate dehydrogenase [NAD] su... | 344 | 4e-115 | 347 | 49 | 69 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 9 | P70404 | 393 | IDHG1_MOUSE Isocitrate dehydrogenase [NAD] su... | 344 | 4e-115 | 347 | 50 | 69 | GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 10 | Q54B68 | 360 | IDHB_DICDI Isocitrate dehydrogenase [NAD] reg... | 328 | 2e-109 | 331 | 52 | 68 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 11 | Q93353 | 379 | IDH3B_CAEEL Probable isocitrate dehydrogenase... | 381 | 1e-108 | 330 | 46 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 12 | O77784 | 385 | IDH3B_BOVIN Isocitrate dehydrogenase [NAD] su... | 358 | 1e-107 | 327 | 46 | 67 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 13 | Q8BPC6 | 396 | IDHG2_MOUSE Probable isocitrate dehydrogenase... | 338 | 1e-107 | 327 | 47 | 67 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 14 | Q4QQT5 | 395 | IDHG2_RAT Probable isocitrate dehydrogenase [... | 338 | 8e-106 | 323 | 46 | 66 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 15 | O43837 | 385 | IDH3B_HUMAN Isocitrate dehydrogenase [NAD] su... | 337 | 1e-105 | 322 | 47 | 69 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; TAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 16 | Q68FX0 | 385 | IDH3B_RAT Isocitrate dehydrogenase [NAD] subu... | 335 | 5e-105 | 320 | 47 | 69 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 17 | Q28479 | 385 | IDH3B_MACFA Isocitrate dehydrogenase [NAD] su... | 335 | 7e-105 | 320 | 47 | 68 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 18 | Q945K7 | 374 | IDH5_ARATH Isocitrate dehydrogenase [NAD] cat... | 333 | 8e-105 | 320 | 48 | 65 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:TAIR.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 19 | Q9VWH4 | 377 | IDH3A_DROME Probable isocitrate dehydrogenase... | 336 | 9e-105 | 320 | 48 | 69 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; ISS:UniProtKB. | 20 | Q8LFC0 | 367 | IDH1_ARATH Isocitrate dehydrogenase [NAD] reg... | 335 | 7e-104 | 317 | 50 | 69 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 21 | Q5RBT4 | 385 | IDH3B_PONAB Isocitrate dehydrogenase [NAD] su... | 335 | 9e-104 | 317 | 47 | 68 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 22 | Q8LG77 | 374 | IDH6_ARATH Isocitrate dehydrogenase [NAD] cat... | 330 | 5e-101 | 310 | 48 | 65 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 23 | P93032 | 367 | IDH2_ARATH Isocitrate dehydrogenase [NAD] reg... | 330 | 6e-101 | 309 | 49 | 68 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 24 | O81796 | 368 | IDH3_ARATH Isocitrate dehydrogenase [NAD] reg... | 335 | 9e-100 | 306 | 49 | 67 | GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IGI:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; IGI:TAIR.::GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR. | 25 | Q93714 | 358 | IDH3A_CAEEL Probable isocitrate dehydrogenase... | 365 | 1e-98 | 303 | 44 | 64 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 26 | Q99NA5 | 366 | IDH3A_RAT Isocitrate dehydrogenase [NAD] subu... | 341 | 9e-96 | 296 | 46 | 65 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 27 | Q28480 | 347 | IDH3A_MACFA Isocitrate dehydrogenase [NAD] su... | 341 | 1e-95 | 295 | 46 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 28 | Q9D6R2 | 366 | IDH3A_MOUSE Isocitrate dehydrogenase [NAD] su... | 341 | 1e-95 | 295 | 46 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 29 | P50213 | 366 | IDH3A_HUMAN Isocitrate dehydrogenase [NAD] su... | 341 | 1e-95 | 295 | 46 | 65 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 30 | P41563 | 366 | IDH3A_BOVIN Isocitrate dehydrogenase [NAD] su... | 341 | 2e-95 | 295 | 46 | 65 | GO:0005739; C:mitochondrion; ISS:AgBase. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 31 | Q5R678 | 366 | IDH3A_PONAB Isocitrate dehydrogenase [NAD] su... | 341 | 2e-95 | 295 | 46 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. |