UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL025C

Length:

323

Number of sequences:

5887

Description:

YNL025C SSN8 SGDID:S000004970, Chr XIV from 585291-584320, Genome Release 64-1-1, reverse complement, Verified ORF, "Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q86KE7	255	CCNC_DICDI Cyclin-C OS=Dictyostelium discoide...	175	8e-24	102	34	54	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:dictyBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32	Q9FJK6	253	CCC11_ARATH Cyclin-C1-1 OS=Arabidopsis thalia...	161	4e-22	97.1	35	56	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
33	P93411	257	CCC11_ORYSJ Cyclin-C1-1 OS=Oryza sativa subsp...	172	7e-21	93.6	33	55	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
34	Q9FJK7	253	CCC12_ARATH Cyclin-C1-2 OS=Arabidopsis thalia...	247	5e-20	90.9	30	48	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
35	Q9TYP2	302	CCNC_CAEEL Cyclin-C OS=Caenorhabditis elegans...	231	2e-18	87	26	48	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36	Q4P101	393	SSN8_USTMA RNA polymerase II holoenzyme cycli...	34	0.0005	45.1	41	82	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37	O88874	554	CCNK_MOUSE Cyclin-K OS=Mus musculus (Mouse). ...	162	0.00000000000003	76.6	31	50
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38	P0C654	298	CCNC_CAEBR Cyclin-C OS=Caenorhabditis briggsa...	230	0.00000000000003	75.1	23	47	GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39	O75909	580	CCNK_HUMAN Cyclin-K OS=Homo sapiens (Human). ...	162	0.00000000000004	76.6	31	50
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
40	Q2QQS5	543	CCT14_ORYSJ Cyclin-T1-4 OS=Oryza sativa subsp...	199	0.0000000000002	74.3	28	47	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
41	Q8GYM6	541	CCT14_ARATH Cyclin-T1-4 OS=Arabidopsis thalia...	199	0.0000000000006	72.8	28	46	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0009615; P:response to virus; IEP:TAIR.::GO:0010090; P:trichome morphogenesis; IMP:TAIR.
42	Q9FKE6	579	CCT15_ARATH Cyclin-T1-5 OS=Arabidopsis thalia...	199	0.000000000001	72	28	48	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009908; P:flower development; IMP:TAIR.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0050792; P:regulation of viral reproduction; IMP:TAIR.::GO:0009615; P:response to virus; IEP:TAIR.::GO:0010090; P:trichome morphogenesis; IMP:TAIR.
43	Q3ZBL9	320	CCNH_BOVIN Cyclin-H OS=Bos taurus (Bovine). G...	285	0.000000000003	69.7	24	45	GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006468; P:protein phosphorylation; ISS:GOC.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
44	Q96S94	520	CCNL2_HUMAN Cyclin-L2 OS=Homo sapiens (Human)...	191	0.000000000006	69.7	26	47	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45	Q9JJA7	518	CCNL2_MOUSE Cyclin-L2 OS=Mus musculus (Mouse)...	191	0.000000000007	69.7	27	46	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46	Q5I0H5	520	CCNL2_RAT Cyclin-L2 OS=Rattus norvegicus (Rat...	191	0.000000000007	69.3	27	46	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47	Q2RAC5	490	CCT13_ORYSJ Cyclin-T1-3 OS=Oryza sativa subsp...	179	0.00000000002	68.2	28	47	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
48	Q5ZJP9	534	CCNL1_CHICK Cyclin-L1 OS=Gallus gallus (Chick...	191	0.00000000003	67.4	27	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49	Q7ZVX0	498	CCNL1_DANRE Cyclin-L1 OS=Danio rerio (Zebrafi...	187	0.00000000004	67.4	25	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50	Q5BKF8	497	CCNL2_XENTR Cyclin-L2 OS=Xenopus tropicalis (...	210	0.00000000006	66.6	24	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51	Q52KE7	532	CCNL1_MOUSE Cyclin-L1 OS=Mus musculus (Mouse)...	180	0.00000000006	66.6	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52	Q9R1Q2	527	CCNL1_RAT Cyclin-L1 OS=Rattus norvegicus (Rat...	180	0.00000000007	66.6	28	48	GO:0016607; C:nuclear speck; IDA:RGD.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; NAS:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53	O74627	342	CG1C_SCHPO Cyclin pch1 OS=Schizosaccharomyces...	188	0.00000000008	65.9	29	45	GO:0005829; C:cytosol; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; TAS:PomBase.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:PomBase.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; TAS:PomBase.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:PomBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; NAS:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; NAS:PomBase.
54	Q9UK58	526	CCNL1_HUMAN Cyclin-L1 OS=Homo sapiens (Human)...	180	0.00000000009	66.2	27	47	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55	Q9QWV9	724	CCNT1_MOUSE Cyclin-T1 OS=Mus musculus (Mouse)...	195	0.0000000003	64.7	26	46	GO:0008024; C:positive transcription elongation factor complex b; TAS:BHF-UCL.
									GO:0003682; F:chromatin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IEA:InterPro.::GO:0017069; F:snRNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56	Q61458	323	CCNH_MOUSE Cyclin-H OS=Mus musculus (Mouse). ...	257	0.0000000003	63.9	24	45	GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
57	Q4R7U4	323	CCNH_MACFA Cyclin-H OS=Macaca fascicularis (C...	257	0.0000000004	63.9	24	44	GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006468; P:protein phosphorylation; ISS:GOC.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
58	P51946	323	CCNH_HUMAN Cyclin-H OS=Homo sapiens (Human). ...	257	0.0000000004	63.5	24	44	GO:0019907; C:cyclin-dependent protein kinase activating kinase holoenzyme complex; IDA:UniProtKB.::GO:0005675; C:holo TFIIH complex; IDA:UniProtKB.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006468; P:protein phosphorylation; IDA:GOC.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.::GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
59	P37366	393	CCL1_YEAST Cyclin CCL1 OS=Saccharomyces cerev...	276	0.0000000009	62.8	25	42	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0070985; C:TFIIK complex; IDA:SGD.
									GO:0016538; F:cyclin-dependent protein kinase regulator activity; IGI:SGD.::GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:SGD.
60	O60583	730	CCNT2_HUMAN Cyclin-T2 OS=Homo sapiens (Human)...	191	0.000000002	62.8	24	46	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
61	Q8RWV3	416	CCL11_ARATH Cyclin-L1-1 OS=Arabidopsis thalia...	177	0.000000002	61.6	24	47	GO:0009506; C:plasmodesma; IDA:TAIR.
									GO:0019901; F:protein kinase binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.::GO:0006396; P:RNA processing; IEA:InterPro.

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