Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL021W
Length:
706
Number of sequences:
5887
Description:
YNL021W HDA1 SGDID:S000004966, Chr XIV from 593227-595347, Genome Release 64-1-1, Verified ORF, "Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O13298    434   PHD1_SCHPO Histone deacetylase phd1 OS=Schizo...3441e-35     143     28     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0034967; C:Set3 complex; IDA:PomBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0060303; P:regulation of nucleosome density; IEP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32Q57955    343   Y535_METJA Uncharacterized protein MJ0535 OS=...3612e-34     138     29     49
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
33P53096    452   HOS2_YEAST Probable histone deacetylase HOS2 ...3312e-31     132     27     50GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0045129; F:NAD-independent histone deacetylase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045835; P:negative regulation of meiosis; IMP:SGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34O59702    405   CLR6_SCHPO Histone deacetylase clr6 OS=Schizo...3323e-31     130     29     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0033698; C:Rpd3L complex; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0032221; C:Rpd3S complex; IDA:PomBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; TAS:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; NAS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35P56517    480   HDAC1_CHICK Histone deacetylase 1 OS=Gallus g...3353e-29     125     28     49
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
36Q56195    385   ACUC_STAXY Acetoin utilization protein AcuC O...3336e-29     123     29     49
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
37Q5RAG0    482   HDAC1_PONAB Histone deacetylase 1 OS=Pongo ab...3358e-29     124     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q13547    482   HDAC1_HUMAN Histone deacetylase 1 OS=Homo sap...3358e-29     124     28     49GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL.
GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0000278; P:mitotic cell cycle; TAS:Reactome.::GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
39Q32PJ8    482   HDAC1_BOVIN Histone deacetylase 1 OS=Bos taur...3351e-28     124     28     49
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
40P32561    433   RPD3_YEAST Histone deacetylase RPD3 OS=Saccha...3261e-28     123     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.::GO:0070211; C:Snt2C complex; IDA:SGD.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; IMP:SGD.::GO:0003714; F:transcription corepressor activity; IMP:SGD.
GO:0070932; P:histone H3 deacetylation; IMP:SGD.::GO:0070933; P:histone H4 deacetylation; IMP:SGD.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:SGD.::GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IDA:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IPI:SGD.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD.
41O09106    482   HDAC1_MOUSE Histone deacetylase 1 OS=Mus musc...3351e-28     123     28     49GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016581; C:NuRD complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0007492; P:endoderm development; IDA:MGI.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0030182; P:neuron differentiation; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q4QQW4    482   HDAC1_RAT Histone deacetylase 1 OS=Rattus nor...3351e-28     123     28     49GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43O42227    480   HDA1B_XENLA Probable histone deacetylase 1-B ...3351e-28     123     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44P64376    389   ACUC_STAAN Acetoin utilization protein AcuC O...3354e-28     120     28     50
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
45P64375    389   ACUC_STAAM Acetoin utilization protein AcuC O...3354e-28     120     28     50
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
46Q5HF39    389   ACUC_STAAC Acetoin utilization protein AcuC O...3359e-28     120     28     50
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
47Q09440    507   HDA2_CAEEL Putative histone deacetylase 2 OS=...3472e-27     120     27     48GO:0000118; C:histone deacetylase complex; ISS:WormBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; ISS:WormBase.
GO:0042262; P:DNA protection; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q8NW34    389   ACUC_STAAW Acetoin utilization protein AcuC O...3355e-27     117     28     49
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
49Q6G8J2    389   ACUC_STAAS Acetoin utilization protein AcuC O...3355e-27     117     28     49
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
50Q6GFX3    389   ACUC_STAAR Acetoin utilization protein AcuC O...3358e-27     117     28     49
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
51Q92769    488   HDAC2_HUMAN Histone deacetylase 2 OS=Homo sap...3531e-26     117     28     49GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032967; P:positive regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52P70288    488   HDAC2_MOUSE Histone deacetylase 2 OS=Mus musc...3532e-26     116     28     49GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005657; C:replication fork; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.::GO:0017053; C:transcriptional repressor complex; IPI:MGI.
GO:0031490; F:chromatin DNA binding; IDA:MGI.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0010977; P:negative regulation of neuron projection development; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53Q3JUN4    341   APHA_BURP1 Acetylpolyamine aminohydrolase OS=...1945e-26     114     37     57
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
54Q91695    480   HDA1A_XENLA Probable histone deacetylase 1-A ...3321e-25     114     27     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q94517    521   HDAC1_DROME Histone deacetylase Rpd3 OS=Droso...3541e-25     115     27     47GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IPI:FlyBase.::GO:0005705; C:polytene chromosome interband; IDA:FlyBase.::GO:0016580; C:Sin3 complex; NAS:FlyBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IPI:FlyBase.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0006342; P:chromatin silencing; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0050771; P:negative regulation of axonogenesis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0022904; P:respiratory electron transport chain; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase.
56Q54VQ7    1704   HDA22_DICDI Type-2 histone deacetylase 2 OS=D...2561e-25     117     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57O17695    461   HDA1_CAEEL Histone deacetylase 1 OS=Caenorhab...2843e-25     113     28     51GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043073; C:germ cell nucleus; IDA:WormBase.::GO:0000118; C:histone deacetylase complex; IPI:WormBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0048557; P:embryonic digestive tract morphogenesis; IGI:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:WormBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; IGI:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0045595; P:regulation of cell differentiation; IGI:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q55BW2    422   HDA12_DICDI Histone deacetylase B OS=Dictyost...3513e-25     112     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:dictyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q55FN5    495   HDA11_DICDI Type-1 histone deacetylase 1 OS=D...3288e-25     112     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60P56521    513   HDA19_MAIZE Probable histone deacetylase 19 O...3383e-24     110     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61P39067    387   ACUC_BACSU Acetoin utilization protein AcuC O...3682e-23     107     28     46
GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
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