Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL020C
Length:
638
Number of sequences:
5887
Description:
YNL020C ARK1 SGDID:S000004965, Chr XIV from 597539-595623, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P27448    753   MARK3_HUMAN MAP/microtubule affinity-regulati...3030.00000000000001     80.9     27     43GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
122Q54MY9    860   MKCA_DICDI Probable serine/threonine-protein ...2750.00000000000001     80.9     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0045595; P:regulation of cell differentiation; IGI:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
123Q5E9L6    487   STK4_BOVIN Serine/threonine-protein kinase 4 ...3770.00000000000001     80.1     24     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
124Q6P4S6    1311   SIK3_MOUSE Serine/threonine-protein kinase SI...2410.00000000000001     81.3     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
125Q9IA88    798   SIK2_CHICK Serine/threonine-protein kinase SI...3090.00000000000002     80.9     27     43GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
126Q7ZUQ3    492   STK3_DANRE Serine/threonine-protein kinase 3 ...2970.00000000000002     80.1     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
127Q02723    502   RKIN1_SECCE Carbon catabolite-derepressing pr...2910.00000000000002     80.1     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
128P53683    533   CDPK2_ORYSJ Calcium-dependent protein kinase ...2810.00000000000002     80.1     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
129Q8VHF0    797   MARK3_RAT MAP/microtubule affinity-regulating...3030.00000000000002     80.5     27     43GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
130Q55FS2    1105   STK4L_DICDI Serine/threonine-protein kinase 4...2880.00000000000002     80.9     27     45GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
131P15735    406   PHKG2_HUMAN Phosphorylase b kinase gamma cata...2350.00000000000002     79.3     27     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.::GO:0045819; P:positive regulation of glycogen catabolic process; TAS:UniProtKB.
132P22987    891   KIN1_SCHPO Protein kinase kin1 OS=Schizosacch...2050.00000000000002     80.5     27     51GO:0032153; C:cell division site; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0015630; C:microtubule cytoskeleton; TAS:PomBase.::GO:0035839; C:non-growing cell tip; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060632; P:regulation of microtubule-based movement; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase.
133Q03002    865   FRK1_YEAST Fatty acyl-CoA synthetase and RNA ...2650.00000000000002     80.5     26     46GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
134Q55BN8    418   NEK2_DICDI Probable serine/threonine-protein ...2820.00000000000002     79.3     27     46GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0007098; P:centrosome cycle; IMP:dictyBase.
135A7J1T2    961   M313A_XENLA Mitogen-activated protein kinase ...1960.00000000000002     80.5     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.
GO:0046777; P:protein autophosphorylation; IEA:InterPro.
136Q1HKZ5    959   M3K13_MOUSE Mitogen-activated protein kinase ...1960.00000000000002     80.5     27     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
137Q8IBS5    528   CDPK4_PLAF7 Calcium-dependent protein kinase ...3310.00000000000002     79.7     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
138Q6IP06    493   STK3_XENLA Serine/threonine-protein kinase 3 ...3100.00000000000002     79.7     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
139E1BK52    966   STK10_BOVIN Serine/threonine-protein kinase 1...2810.00000000000002     80.5     26     47GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
140O13839    722   FIN1_SCHPO G2-specific protein kinase fin1 OS...3280.00000000000002     80.1     27     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0071958; C:new spindle pole body; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0007076; P:mitotic chromosome condensation; IMP:PomBase.::GO:0031030; P:negative regulation of septation initiation signaling cascade; IMP:PomBase.::GO:0031028; P:septation initiation signaling cascade; IMP:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; IMP:PomBase.
141O43283    966   M3K13_HUMAN Mitogen-activated protein kinase ...1960.00000000000003     80.1     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
142Q8BTW9    593   PAK4_MOUSE Serine/threonine-protein kinase PA...1960.00000000000003     79.7     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
143Q5R8X7    966   M3K13_PONAB Mitogen-activated protein kinase ...1960.00000000000003     80.1     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
144E9PTG8    967   STK10_RAT Serine/threonine-protein kinase 10 ...2810.00000000000003     80.1     25     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
145O55098    966   STK10_MOUSE Serine/threonine-protein kinase 1...2810.00000000000003     79.7     25     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
146B0LT89    431   STK24_RAT Serine/threonine-protein kinase 24 ...2170.00000000000003     78.6     31     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0048680; P:positive regulation of axon regeneration; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
147Q9CAU7    606   NEK2_ARATH Serine/threonine-protein kinase Ne...2540.00000000000003     79.3     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
148Q8CIP4    752   MARK4_MOUSE MAP/microtubule affinity-regulati...1960.00000000000004     79.7     29     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0043005; C:neuron projection; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007399; P:nervous system development; ISS:UniProtKB.
149O97143    769   PLK4_DROME Serine/threonine-protein kinase PL...2740.00000000000004     79.7     26     44GO:0005814; C:centriole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase.
150O22971    502   CIPKD_ARATH CBL-interacting serine/threonine-...2850.00000000000004     79     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
151Q60670    779   SIK1_MOUSE Serine/threonine-protein kinase SI...2480.00000000000004     79.3     27     44GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0055007; P:cardiac muscle cell differentiation; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; IDA:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; IDA:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
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