UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL007C

Length:

352

Number of sequences:

5887

Description:

YNL007C SIS1 SGDID:S000004952, Chr XIV from 619565-618507, Genome Release 64-1-1, reverse complement, Verified ORF, "Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
841	C3P8L9	371	DNAJ_BACAA Chaperone protein DnaJ OS=Bacillus...	82	0.0006	44.7	27	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
842	Q634M8	371	DNAJ_BACCZ Chaperone protein DnaJ OS=Bacillus...	82	0.0006	45.1	27	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
843	C1ESK7	371	DNAJ_BACC3 Chaperone protein DnaJ OS=Bacillus...	82	0.0006	45.1	27	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
844	B7JN38	371	DNAJ_BACC0 Chaperone protein DnaJ OS=Bacillus...	82	0.0006	45.1	27	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
845	Q4R8H2	621	DNJC2_MACFA DnaJ homolog subfamily C member 2...	131	0.0006	45.4	25	41	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
846	Q7TQ20	621	DNJC2_RAT DnaJ homolog subfamily C member 2 O...	131	0.0006	45.4	25	41	GO:0005829; C:cytosol; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; IDA:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
847	Q9SAG8	163	DNAJ8_ARATH Chaperone protein dnaJ 8, chlorop...	50	0.0006	43.1	40	64	GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0009416; P:response to light stimulus; IEP:TAIR.::GO:0006950; P:response to stress; IMP:TAIR.
848	Q1RMH9	621	DNJC2_BOVIN DnaJ homolog subfamily C member 2...	131	0.0007	45.1	25	41	GO:0005829; C:cytosol; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
849	Q6CW35	653	JJJ2_KLULA J protein JJJ2 OS=1267 / NRRL Y-11...	94	0.0007	45.1	31	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
850	Q9KUR8	284	DJLA_VIBCH DnaJ-like protein DjlA OS=Vibrio c...	59	0.0007	44.3	37	58	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0051087; F:chaperone binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
851	Q99543	621	DNJC2_HUMAN DnaJ homolog subfamily C member 2...	97	0.0007	45.1	29	47	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.
									GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
									GO:0051083; P:'de novo' cotranslational protein folding; TAS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
852	P32527	433	ZUO1_YEAST Zuotin OS=Saccharomyces cerevisiae...	78	0.0008	44.7	38	51	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005730; C:nucleolus; IMP:SGD.::GO:0005844; C:polysome; IDA:SGD.::GO:0005840; C:ribosome; IDA:SGD.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; NAS:SGD.
									GO:0006457; P:protein folding; NAS:SGD.::GO:0006450; P:regulation of translational fidelity; IMP:SGD.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
853	Q0A7E4	383	DNAJ_ALHEH Chaperone protein DnaJ OS=Alkalili...	139	0.0009	44.3	27	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
854	Q8N4W6	341	DJC22_HUMAN DnaJ homolog subfamily C member 2...	57	0.0009	44.3	35	58	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
855	P17631	375	DNAJ_BACSU Chaperone protein DnaJ OS=Bacillus...	136	0.001	43.9	26	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
856	Q9RDD7	378	DNAJ2_STRCO Chaperone protein DnaJ 2 OS=Strep...	138	0.001	43.9	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
857	Q6CUQ9	162	DPH4_KLULA Diphthamide biosynthesis protein 4...	88	0.001	42.7	30	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
858	Q8IM77	492	YPFJ1_PLAF7 Uncharacterized J domain-containi...	67	0.001	44.3	31	63	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
859	Q6IMK3	273	DJC27_DANRE DnaJ homolog subfamily C member 2...	46	0.001	43.5	43	59
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
860	Q9P7C1	303	YKU3_SCHPO Uncharacterized J domain-containin...	60	0.001	43.5	33	55	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
861	Q5FGQ8	382	DNAJ_EHRRG Chaperone protein DnaJ OS=Ehrlichi...	138	0.002	43.1	24	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
862	Q5HCG4	382	DNAJ_EHRRW Chaperone protein DnaJ OS=Ehrlichi...	138	0.002	43.1	24	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
863	A1WAR7	376	DNAJ_ACISJ Chaperone protein DnaJ OS=Acidovor...	134	0.002	43.5	25	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
864	A1TLH8	378	DNAJ_ACIAC Chaperone protein DnaJ OS=citrulli...	134	0.002	43.5	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
865	Q5FSL4	380	DNAJ_GLUOX Chaperone protein DnaJ OS=Gluconob...	142	0.002	43.5	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
866	Q6F150	374	DNAJ_MESFL Chaperone protein DnaJ OS=(Acholep...	159	0.002	43.1	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
867	O67623	364	DNAJ1_AQUAE Chaperone protein DnaJ 1 OS=Aquif...	140	0.002	43.5	24	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
868	Q75WD2	380	DNAJ_ACEP3 Chaperone protein DnaJ OS=Acetobac...	147	0.002	43.5	24	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
869	Q17433	337	DNJ2_CAEEL DnaJ homolog dnj-2 OS=Caenorhabdit...	68	0.002	43.5	37	54	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
870	Q9NZQ0	273	DJC27_HUMAN DnaJ homolog subfamily C member 2...	46	0.002	42.7	43	59
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
871	A5D7F5	273	DJC27_BOVIN DnaJ homolog subfamily C member 2...	46	0.002	42.7	43	59
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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