Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL006W
Length:
303
Number of sequences:
5887
Description:
YNL006W LST8 SGDID:S000004951, Chr XIV from 620067-620978, Genome Release 64-1-1, Verified ORF, "Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P41318    303   LST8_YEAST Target of rapamycin complex subuni...3030     631     100     100GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD.
2O74184    314   WAT1_SCHPO WD repeat-containing protein wat1 ...3022e-155     444     67     81GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
3Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...3027e-115     340     51     71GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
4Q9DCJ1    326   LST8_MOUSE Target of rapamycin complex subuni...3125e-101     306     48     65
GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.
5Q803V5    326   LST8_DANRE Target of rapamycin complex subuni...3121e-100     305     48     65GO:0005737; C:cytoplasm; ISS:UniProtKB.
6Q17QU5    326   LST8_BOVIN Target of rapamycin complex subuni...3122e-100     304     48     65GO:0005737; C:cytoplasm; ISS:UniProtKB.
7Q6PA72    326   LST8_XENLA Target of rapamycin complex subuni...3124e-100     303     48     65GO:0005737; C:cytoplasm; ISS:UniProtKB.
8Q9BVC4    326   LST8_HUMAN Target of rapamycin complex subuni...3124e-100     303     47     65GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.
9Q5I0B4    326   LST8_XENTR Target of rapamycin complex subuni...3125e-100     303     48     65GO:0005737; C:cytoplasm; ISS:UniProtKB.
10Q9Z2K5    326   LST8_RAT Target of rapamycin complex subunit ...3125e-98     298     47     64GO:0005829; C:cytosol; IDA:RGD.
11Q9W328    313   LST8_DROME Protein LST8 homolog OS=Drosophila...3043e-76     242     42     60GO:0005737; C:cytoplasm; ISS:UniProtKB.
12Q29HG9    315   LST8_DROPS Protein LST8 homolog OS=Drosophila...3064e-76     241     42     60GO:0005737; C:cytoplasm; ISS:UniProtKB.
13Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1560.000000002     62     27     47
14Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...1520.0000000000001     74.7     28     49
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
15Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...1040.00000007     57.4     30     57
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
16Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...1510.00000001     59.3     25     46GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
17Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...1800.000000002     62     26     46
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
18P74442    1191   Y143_SYNY3 Uncharacterized WD repeat-containi...1210.003     42.7     21     42
19Q5BK30    415   WDR69_RAT Outer row dynein assembly protein 1...1000.0009     44.3     30     45GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
20Q8N136    415   WDR69_HUMAN Outer row dynein assembly protein...1000.001     43.9     28     46GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
21Q55563    1693   Y163_SYNY3 Uncharacterized WD repeat-containi...940.03     39.7     30     44
GO:0005488; F:binding; IEA:InterPro.
22D3TLL6    411   LIS1_GLOMM Lissencephaly-1 homolog OS=Glossin...1030.000002     52.4     30     50GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
23O76734    579   TUP1_DICDI General transcriptional corepresso...1070.0000005     54.7     34     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...1000.0007     44.7     29     46GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
25P49695    742   PKWA_THECU Probable serine/threonine-protein ...970.000003     52     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
26Q5FWQ6    415   WDR69_XENLA Outer row dynein assembly protein...1540.002     42.7     23     38GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
27Q9PTR5    410   LIS1_CHICK Lissencephaly-1 homolog OS=Gallus ...1060.00001     50.1     30     46
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
28Q6P2Y2    415   WDR69_XENTR Outer row dynein assembly protein...1540.0007     44.7     24     39GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
29P63004    410   LIS1_RAT Platelet-activating factor acetylhyd...1060.000009     50.4     30     46GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD.
GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD.
GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD.
30P63005    410   LIS1_MOUSE Platelet-activating factor acetylh...1060.000009     50.4     30     46GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.
31B0LSW3    410   LIS1_FELCA Platelet-activating factor acetylh...1060.000009     50.4     30     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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