rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P41318 | 303 | LST8_YEAST Target of rapamycin complex subuni... | 303 | 0 | 631 | 100 | 100 | GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD. | 2 | O74184 | 314 | WAT1_SCHPO WD repeat-containing protein wat1 ... | 302 | 2e-155 | 444 | 67 | 81 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 3 | Q54D08 | 304 | LST8_DICDI Protein LST8 homolog OS=Dictyostel... | 302 | 7e-115 | 340 | 51 | 71 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase. | 4 | Q9DCJ1 | 326 | LST8_MOUSE Target of rapamycin complex subuni... | 312 | 5e-101 | 306 | 48 | 65 | | | | | | | | | | | | | | | | | | | | | GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI. | 5 | Q803V5 | 326 | LST8_DANRE Target of rapamycin complex subuni... | 312 | 1e-100 | 305 | 48 | 65 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 6 | Q17QU5 | 326 | LST8_BOVIN Target of rapamycin complex subuni... | 312 | 2e-100 | 304 | 48 | 65 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 7 | Q6PA72 | 326 | LST8_XENLA Target of rapamycin complex subuni... | 312 | 4e-100 | 303 | 48 | 65 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 8 | Q9BVC4 | 326 | LST8_HUMAN Target of rapamycin complex subuni... | 312 | 4e-100 | 303 | 47 | 65 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 9 | Q5I0B4 | 326 | LST8_XENTR Target of rapamycin complex subuni... | 312 | 5e-100 | 303 | 48 | 65 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 10 | Q9Z2K5 | 326 | LST8_RAT Target of rapamycin complex subunit ... | 312 | 5e-98 | 298 | 47 | 64 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | | | | | | | | | | | | 11 | Q9W328 | 313 | LST8_DROME Protein LST8 homolog OS=Drosophila... | 304 | 3e-76 | 242 | 42 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 12 | Q29HG9 | 315 | LST8_DROPS Protein LST8 homolog OS=Drosophila... | 306 | 4e-76 | 241 | 42 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 13 | Q8YRI1 | 1526 | YY46_NOSS1 Uncharacterized WD repeat-containi... | 156 | 0.000000002 | 62 | 27 | 47 | | | | | | | | | | | | | | | | | | | | | | 14 | Q00808 | 1356 | HETE1_PODAS Vegetative incompatibility protei... | 152 | 0.0000000000001 | 74.7 | 28 | 49 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q8YTC2 | 1258 | Y2800_NOSS1 Uncharacterized WD repeat-contain... | 104 | 0.00000007 | 57.4 | 30 | 57 | | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:InterPro. | 16 | Q54KL5 | 335 | WDR5_DICDI WD repeat-containing protein 5 hom... | 151 | 0.00000001 | 59.3 | 25 | 46 | GO:0035097; C:histone methyltransferase complex; ISS:dictyBase. | | | | | | | | | | GO:0042393; F:histone binding; ISS:dictyBase. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase. | 17 | Q8YV57 | 1683 | Y2124_NOSS1 Uncharacterized WD repeat-contain... | 180 | 0.000000002 | 62 | 26 | 46 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 18 | P74442 | 1191 | Y143_SYNY3 Uncharacterized WD repeat-containi... | 121 | 0.003 | 42.7 | 21 | 42 | | | | | | | | | | | | | | | | | | | | | | 19 | Q5BK30 | 415 | WDR69_RAT Outer row dynein assembly protein 1... | 100 | 0.0009 | 44.3 | 30 | 45 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 20 | Q8N136 | 415 | WDR69_HUMAN Outer row dynein assembly protein... | 100 | 0.001 | 43.9 | 28 | 46 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 21 | Q55563 | 1693 | Y163_SYNY3 Uncharacterized WD repeat-containi... | 94 | 0.03 | 39.7 | 30 | 44 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 22 | D3TLL6 | 411 | LIS1_GLOMM Lissencephaly-1 homolog OS=Glossin... | 103 | 0.000002 | 52.4 | 30 | 50 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 23 | O76734 | 579 | TUP1_DICDI General transcriptional corepresso... | 107 | 0.0000005 | 54.7 | 34 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q0P593 | 415 | WDR69_BOVIN Outer row dynein assembly protein... | 100 | 0.0007 | 44.7 | 29 | 46 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 25 | P49695 | 742 | PKWA_THECU Probable serine/threonine-protein ... | 97 | 0.000003 | 52 | 29 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q5FWQ6 | 415 | WDR69_XENLA Outer row dynein assembly protein... | 154 | 0.002 | 42.7 | 23 | 38 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 27 | Q9PTR5 | 410 | LIS1_CHICK Lissencephaly-1 homolog OS=Gallus ... | 106 | 0.00001 | 50.1 | 30 | 46 | | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 28 | Q6P2Y2 | 415 | WDR69_XENTR Outer row dynein assembly protein... | 154 | 0.0007 | 44.7 | 24 | 39 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 29 | P63004 | 410 | LIS1_RAT Platelet-activating factor acetylhyd... | 106 | 0.000009 | 50.4 | 30 | 46 | GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD. | | | | | | | | | | GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD. | | | | | | | | | | GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD. | 30 | P63005 | 410 | LIS1_MOUSE Platelet-activating factor acetylh... | 106 | 0.000009 | 50.4 | 30 | 46 | GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI. | | | | | | | | | | GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI. | 31 | B0LSW3 | 410 | LIS1_FELCA Platelet-activating factor acetylh... | 106 | 0.000009 | 50.4 | 30 | 46 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. |