Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL004W
Length:
454
Number of sequences:
5887
Description:
YNL004W HRB1 SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-1-1, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q4V7Y4    286   DAZLB_XENLA Deleted in azoospermia-like-B OS=...776.4     32.7     27     49GO:0032019; C:mitochondrial cloud; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0008494; F:translation activator activity; ISS:UniProtKB.
GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0008354; P:germ cell migration; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
512Q62376    448   RU17_MOUSE U1 small nuclear ribonucleoprotein...740.33     37     27     47GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
513Q2HJG2    530   PUF60_BOVIN Poly(U)-binding-splicing factor P...1850.34     37     19     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
514Q9NQ94    594   A1CF_HUMAN APOBEC1 complementation factor OS=...605.8     33.1     30     52GO:0030895; C:apolipoprotein B mRNA editing enzyme complex; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
GO:0016554; P:cytidine to uridine editing; TAS:Reactome.::GO:0016556; P:mRNA modification; TAS:Reactome.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050821; P:protein stabilization; IDA:UniProtKB.
515Q5R9H4    587   A1CF_PONAB APOBEC1 complementation factor OS=...605.4     33.1     30     52GO:0030895; C:apolipoprotein B mRNA editing enzyme complex; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050821; P:protein stabilization; ISS:UniProtKB.
516P26369    475   U2AF2_MOUSE Splicing factor U2AF 65 kDa subun...2320.35     37     20     42GO:0016607; C:nuclear speck; TAS:UniProtKB.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IDA:UniProtKB.
517Q4WAQ9    459   PPIL4_ASPFU Peptidyl-prolyl cis-trans isomera...740.35     37     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
518Q6DES0    153   NCBP2_XENTR Nuclear cap-binding protein subun...750.35     35.4     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
519Q2U256    461   PPIL4_ASPOR Peptidyl-prolyl cis-trans isomera...740.35     37     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
520Q55GD6    359   SF3B4_DICDI Splicing factor 3B subunit 4 OS=D...1700.36     36.6     26     39GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:dictyBase.
521Q5SP50    218   ZCRB1_DANRE Zinc finger CCHC-type and RNA-bin...670.36     36.2     33     46GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
522O00425    579   IF2B3_HUMAN Insulin-like growth factor 2 mRNA...1730.37     37     19     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0045182; F:translation regulator activity; ISS:BHF-UCL.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.::GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.::GO:0006412; P:translation; TAS:ProtInc.
523P21522    342   ROA1_SCHAM Heterogeneous nuclear ribonucleopr...1800.46     36.2     23     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
524Q4R979    364   RBM4_MACFA RNA-binding protein 4 OS=Macaca fa...745.8     32.7     26     46GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0035198; F:miRNA binding; ISS:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0036002; F:pre-mRNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032055; P:negative regulation of translation in response to stress; ISS:UniProtKB.::GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; ISS:UniProtKB.::GO:0045947; P:negative regulation of translational initiation; ISS:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0046822; P:regulation of nucleocytoplasmic transport; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB.
525Q9BWF3    364   RBM4_HUMAN RNA-binding protein 4 OS=Homo sapi...745.8     32.7     26     46GO:0010494; C:cytoplasmic stress granule; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0035198; F:miRNA binding; IDA:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032055; P:negative regulation of translation in response to stress; IDA:UniProtKB.::GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.::GO:0045947; P:negative regulation of translational initiation; IDA:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0046822; P:regulation of nucleocytoplasmic transport; IDA:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
526B4JUT1    154   NCBP2_DROGR Nuclear cap-binding protein subun...780.38     35.4     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
527B4LZ88    154   NCB2B_DROVI Nuclear cap-binding protein subun...780.38     35.4     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
528Q8JIY8    269   MK67I_DANRE MKI67 FHA domain-interacting nucl...675.7     32.7     30     45GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
529Q5R9L3    482   G3BP2_PONAB Ras GTPase-activating protein-bin...600.39     37     38     50
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
530Q9UN86    482   G3BP2_HUMAN Ras GTPase-activating protein-bin...600.39     37     38     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.
GO:0007253; P:cytoplasmic sequestering of NF-kappaB; NAS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
531Q05AT9    272   U1SBP_XENLA U11/U12 small nuclear ribonucleop...1160.39     36.2     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
532B4N1L0    269   EI3G1_DROWI Eukaryotic translation initiation...880.39     36.2     33     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
533P97379    482   G3BP2_MOUSE Ras GTPase-activating protein-bin...600.4     36.6     38     50
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
534Q3MHX3    362   RBM4_BOVIN RNA-binding protein 4 OS=Bos tauru...746     32.7     26     46GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0035198; F:miRNA binding; ISS:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0036002; F:pre-mRNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032055; P:negative regulation of translation in response to stress; ISS:UniProtKB.::GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; ISS:UniProtKB.::GO:0045947; P:negative regulation of translational initiation; ISS:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0046822; P:regulation of nucleocytoplasmic transport; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB.
535Q1RMR2    439   RU17_BOVIN U1 small nuclear ribonucleoprotein...730.4     36.6     27     48GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
536Q9BX46    236   RBM24_HUMAN RNA-binding protein 24 OS=Homo sa...600.41     36.2     35     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.
537Q7ZWA3    379   RBMX_DANRE RNA-binding motif protein, X chrom...740.41     36.6     26     47GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
538Q4KMD7    797   STPAP_DANRE Speckle targeted PIP5K1A-regulate...600.41     37     35     53GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0050265; F:RNA uridylyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006379; P:mRNA cleavage; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0016180; P:snRNA processing; ISS:UniProtKB.
539Q5XI01    571   LARP7_RAT La-related protein 7 OS=Rattus norv...670.41     37     34     46GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:InterPro.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006396; P:RNA processing; IEA:InterPro.
540B4MA85    269   EI3G1_DROVI Eukaryotic translation initiation...880.41     36.2     33     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
541A7SKE9    294   EIF3G_NEMVE Eukaryotic translation initiation...755.6     32.7     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
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