Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL004W
Length:
454
Number of sequences:
5887
Description:
YNL004W HRB1 SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-1-1, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361O88477    577   IF2B1_MOUSE Insulin-like growth factor 2 mRNA...1770.026     40.4     19     42GO:0070937; C:CRD-mediated mRNA stability complex; ISS:UniProtKB.::GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0010610; P:regulation of mRNA stability involved in response to stress; ISS:UniProtKB.
362Q9NZI8    577   IF2B1_HUMAN Insulin-like growth factor 2 mRNA...1770.027     40.4     19     42GO:0070937; C:CRD-mediated mRNA stability complex; IDA:UniProtKB.::GO:0010494; C:cytoplasmic stress granule; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0045182; F:translation regulator activity; IDA:BHF-UCL.
GO:0070934; P:CRD-mediated mRNA stabilization; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:BHF-UCL.::GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.::GO:0010610; P:regulation of mRNA stability involved in response to stress; IMP:UniProtKB.
363Q8CGX0    577   IF2B1_RAT Insulin-like growth factor 2 mRNA-b...1770.028     40.4     19     42GO:0070937; C:CRD-mediated mRNA stability complex; ISS:UniProtKB.::GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0010610; P:regulation of mRNA stability involved in response to stress; ISS:UniProtKB.::GO:0006403; P:RNA localization; IMP:RGD.
364Q5XG24    283   RNP1A_XENLA RNA-binding protein with serine-r...660.029     40     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
365Q0WMY5    952   PP365_ARATH Pentatricopeptide repeat-containi...800.029     40.4     34     51GO:0009507; C:chloroplast; IDA:TAIR.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
366P51968    373   RO31_XENLA Heterogeneous nuclear ribonucleopr...950.031     40     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
367Q3KPW1    283   RNP1B_XENLA RNA-binding protein with serine-r...660.031     39.7     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
368Q58EA2    256   THO4A_XENLA THO complex subunit 4-A OS=Xenopu...1304.2     33.1     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
369P32588    453   PUB1_YEAST Nuclear and cytoplasmic polyadenyl...944.8     33.1     23     45GO:0010494; C:cytoplasmic stress granule; IDA:SGD.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; IDA:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:SGD.::GO:0043488; P:regulation of mRNA stability; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.
370Q6PG31    283   RNPS1_DANRE RNA-binding protein with serine-r...650.033     39.7     28     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
371Q2R0Q1    574   U2A2A_ORYSJ Splicing factor U2af large subuni...2130.033     40.4     21     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
372Q28FB9    260   THOC4_XENTR THO complex subunit 4 OS=Xenopus ...810.033     39.7     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
373Q28E41    309   RNPS1_XENTR RNA-binding protein with serine-r...650.034     39.7     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
374O42254    576   IF2B1_CHICK Insulin-like growth factor 2 mRNA...1730.036     40     20     42GO:0070937; C:CRD-mediated mRNA stability complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
375Q13148    414   TADBP_HUMAN TAR DNA-binding protein 43 OS=Hom...833.5     33.5     31     46GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.::GO:0003730; F:mRNA 3'-UTR binding; IDA:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:BHF-UCL.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043922; P:negative regulation by host of viral transcription; IDA:BHF-UCL.::GO:0008380; P:RNA splicing; IDA:BHF-UCL.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
376Q43472    161   GRP_HORVU Glycine-rich RNA-binding protein bl...794.5     32.3     28     52
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IDA:UniProtKB.::GO:0009409; P:response to cold; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
377P53316    781   YG5B_YEAST Uncharacterized RNA-binding protei...950.038     40     29     44GO:0010494; C:cytoplasmic stress granule; IDA:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
378P98179    157   RBM3_HUMAN Putative RNA-binding protein 3 OS=...720.038     38.5     29     49GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.
GO:0045727; P:positive regulation of translation; ISS:UniProtKB.
379Q5R5W2    414   TADBP_PONAB TAR DNA-binding protein 43 OS=Pon...833.4     33.5     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
380O89086    153   RBM3_MOUSE Putative RNA-binding protein 3 OS=...720.038     38.5     29     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043023; F:ribosomal large subunit binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; IDA:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0006412; P:translation; IDA:MGI.
381Q503H1    314   TSAP1_DANRE tRNA selenocysteine 1-associated ...1690.039     39.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006412; P:translation; IEA:UniProtKB-KW.
382Q07652    2222   CAC1E_RAT Voltage-dependent R-type calcium ch...980.039     40.4     34     48GO:0043204; C:perikaryon; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; TAS:RGD.
GO:0008332; F:low voltage-gated calcium channel activity; TAS:RGD.
383Q93594    154   NCBP2_CAEEL Nuclear cap-binding protein subun...620.042     38.1     31     52GO:0005635; C:nuclear envelope; IDA:WormBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
384P51992    385   RO32_XENLA Heterogeneous nuclear ribonucleopr...781.6     34.7     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
385P19339    354   SXL_DROME Protein sex-lethal OS=Drosophila me...1700.54     36.2     24     40GO:0043234; C:protein complex; IPI:FlyBase.
GO:0008083; F:growth factor activity; IDA:FlyBase.::GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase.::GO:0048027; F:mRNA 5'-UTR binding; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:FlyBase.::GO:0000900; F:translation repressor activity, nucleic acid binding; TAS:FlyBase.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; TAS:FlyBase.::GO:0007549; P:dosage compensation; NAS:FlyBase.::GO:0019099; P:female germ-line sex determination; TAS:FlyBase.::GO:0019101; P:female somatic sex determination; TAS:FlyBase.::GO:0007281; P:germ cell development; TAS:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; TAS:FlyBase.::GO:0009994; P:oocyte differentiation; IDA:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; TAS:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007541; P:sex determination, primary response to X:A ratio; TAS:FlyBase.::GO:0007548; P:sex differentiation; NAS:FlyBase.::GO:0007224; P:smoothened signaling pathway; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
386Q61290    2272   CAC1E_MOUSE Voltage-dependent R-type calcium ...980.047     40     34     48GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
387Q5RC80    524   RBM39_PONAB RNA-binding protein 39 OS=Pongo a...833.3     33.9     31     43GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
388P0C196    551   PPIL4_USTMA Peptidyl-prolyl cis-trans isomera...780.048     39.7     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
389Q9SX79    432   RB47C_ARATH Polyadenylate-binding protein RBP...3020.29     37     21     38GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0034605; P:cellular response to heat; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
390P49960    444   PRP24_YEAST U4/U6 snRNA-associated-splicing f...2224.2     33.5     23     40GO:0005688; C:U6 snRNP; IDA:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0017070; F:U6 snRNA binding; IDA:SGD.
GO:0000244; P:assembly of spliceosomal tri-snRNP; IDA:SGD.::GO:0000245; P:spliceosomal complex assembly; IMP:SGD.
391A8Y1R8    157   NCBP2_CAEBR Nuclear cap-binding protein subun...620.05     38.1     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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