Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL004W
Length:
454
Number of sequences:
5887
Description:
YNL004W HRB1 SGDID:S000004949, Chr XIV from 622915-622944,623287-624621, Genome Release 64-1-1, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241P60824    172   CIRBP_MOUSE Cold-inducible RNA-binding protei...860.56     35.4     31     51GO:0010494; C:cytoplasmic stress granule; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0070181; F:SSU rRNA binding; ISS:UniProtKB.::GO:0030371; F:translation repressor activity; IDA:UniProtKB.
GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0034063; P:stress granule assembly; IDA:UniProtKB.
242P60826    172   CIRBP_CRIGR Cold-inducible RNA-binding protei...860.56     35.4     31     51GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0070181; F:SSU rRNA binding; ISS:UniProtKB.::GO:0030371; F:translation repressor activity; ISS:UniProtKB.
GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0034063; P:stress granule assembly; ISS:UniProtKB.
243Q10355    219   YDB2_SCHPO Uncharacterized RNA-binding protei...690.0009     44.3     35     54GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007126; P:meiosis; IEP:PomBase.
244Q7SG09    827   MRD1_NEUCR Multiple RNA-binding domain-contai...3130.001     45.4     25     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
245Q5NVM8    305   RNPS1_PONAB RNA-binding protein with serine-r...630.001     44.7     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
246Q99M28    305   RNPS1_MOUSE RNA-binding protein with serine-r...630.001     44.7     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
247Q4R5N1    305   RNPS1_MACFA RNA-binding protein with serine-r...630.001     44.7     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
248Q15287    305   RNPS1_HUMAN RNA-binding protein with serine-r...630.001     44.7     33     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
249A6QR16    305   RNPS1_BOVIN RNA-binding protein with serine-r...630.001     44.7     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
250P09651    372   ROA1_HUMAN Heterogeneous nuclear ribonucleopr...782.7     33.9     27     47GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:HGNC.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003697; F:single-stranded DNA binding; IDA:HGNC.::GO:0003727; F:single-stranded RNA binding; IC:HGNC.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0051170; P:nuclear import; IDA:HGNC.::GO:0006405; P:RNA export from nucleus; IC:HGNC.
251A5A6H4    320   ROA1_PANTR Heterogeneous nuclear ribonucleopr...782.6     33.9     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
252P49312    320   ROA1_MOUSE Heterogeneous nuclear ribonucleopr...782.6     33.9     27     47GO:0005737; C:cytoplasm; ISS:HGNC.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0005681; C:spliceosomal complex; ISS:HGNC.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; ISS:HGNC.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IDA:MGI.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0051168; P:nuclear export; ISS:HGNC.::GO:0051170; P:nuclear import; ISS:HGNC.
253P09867    320   ROA1_BOVIN Heterogeneous nuclear ribonucleopr...782.6     33.9     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
254Q6AYK1    305   RNPS1_RAT RNA-binding protein with serine-ric...630.001     44.7     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
255P04256    320   ROA1_RAT Heterogeneous nuclear ribonucleoprot...783.7     33.5     27     46GO:0005737; C:cytoplasm; ISS:HGNC.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0005681; C:spliceosomal complex; ISS:HGNC.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:RGD.::GO:0003697; F:single-stranded DNA binding; ISS:HGNC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0051168; P:nuclear export; ISS:HGNC.::GO:0051170; P:nuclear import; ISS:HGNC.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
256Q99020    285   ROAA_MOUSE Heterogeneous nuclear ribonucleopr...801.3     34.7     25     44GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HGNC.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:HGNC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0001837; P:epithelial to mesenchymal transition; IDA:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:HGNC.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
257Q9SVM8    158   GRP2_ARATH Glycine-rich RNA-binding protein 2...860.001     43.1     34     45GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0003690; F:double-stranded DNA binding; IDA:TAIR.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IDA:TAIR.
GO:0009409; P:response to cold; IMP:TAIR.::GO:0006970; P:response to osmotic stress; IMP:TAIR.::GO:0009845; P:seed germination; IMP:TAIR.
258Q9JJ43    396   RFOX1_MOUSE RNA binding protein fox-1 homolog...1030.019     40.8     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
259P23246    707   SFPQ_HUMAN Splicing factor, proline- and glut...710.19     37.7     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0042382; C:paraspeckles; IDA:BHF-UCL.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IMP:BHF-UCL.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
260Q32P51    320   RA1L2_HUMAN Heterogeneous nuclear ribonucleop...940.007     42     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
261Q9ZR40    573   U2A2B_NICPL Splicing factor U2af large subuni...2180.001     44.7     21     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
262Q28521    320   ROA1_MACMU Heterogeneous nuclear ribonucleopr...789.2     32.3     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
263Q9DED4    166   CIRBB_XENLA Cold-inducible RNA-binding protei...740.001     42.7     32     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0048255; P:mRNA stabilization; IMP:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0009409; P:response to cold; ISS:UniProtKB.
264Q99070    168   GRP2_SORBI Glycine-rich RNA-binding protein 2...730.001     42.7     34     51
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
265P51990    358   RO22_XENLA Heterogeneous nuclear ribonucleopr...950.001     44.3     31     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
266Q8VIJ6    699   SFPQ_MOUSE Splicing factor, proline- and glut...710.21     37.7     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
267Q6CQR6    878   MRD1_KLULA Multiple RNA-binding domain-contai...2000.005     43.1     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
268Q43349    342   ROC2_ARATH 29 kDa ribonucleoprotein, chloropl...756.5     32.7     32     51GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0009534; C:chloroplast thylakoid; IDA:TAIR.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:TAIR.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
269Q6FVV7    443   RRT5_CANGA Regulator of rDNA transcription pr...1010.002     44.3     33     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
270Q94901    352   LARK_DROME RNA-binding protein lark OS=Drosop...800.081     38.9     29     46GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:UniProtKB.::GO:0008062; P:eclosion rhythm; IMP:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0045475; P:locomotor rhythm; TAS:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0045804; P:negative regulation of eclosion; IMP:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0008104; P:protein localization; IMP:UniProtKB.
271Q920Q6    346   MSI2H_MOUSE RNA-binding protein Musashi homol...600.005     42.7     37     57GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005844; C:polysome; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:MGI.
GO:0048864; P:stem cell development; IMP:UniProtKB.
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