Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR314W
Length:
234
Number of sequences:
5887
Description:
YMR314W PRE5 SGDID:S000004931, Chr XIII from 901709-902413, Genome Release 64-1-1, Verified ORF, "Alpha 6 subunit of the 20S proteasome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151O81147    246   PSA6B_ARATH Proteasome subunit alpha type-6-B...2252e-21     93.6     28     47GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
152Q54XM7    250   PSA6_DICDI Proteasome subunit alpha type-6 OS...2342e-21     93.6     31     47GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
153Q9LSU0    249   PSA3_ORYSJ Proteasome subunit alpha type-3 OS...1734e-21     92.8     31     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
154O24362    249   PSA3_SPIOL Proteasome subunit alpha type-3 OS...1744e-21     92.8     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
155O23715    249   PSA3_ARATH Proteasome subunit alpha type-3 OS...1736e-21     92.4     31     48GO:0048046; C:apoplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
156Q58DU5    255   PSA3_BOVIN Proteasome subunit alpha type-3 OS...1781e-19     88.6     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
157O70435    255   PSA3_MOUSE Proteasome subunit alpha type-3 OS...1781e-19     88.6     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
158P25788    255   PSA3_HUMAN Proteasome subunit alpha type-3 OS...1781e-19     88.6     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
159P18422    255   PSA3_RAT Proteasome subunit alpha type-3 OS=R...1781e-19     88.6     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
160P60901    246   PSA6_RAT Proteasome subunit alpha type-6 OS=R...2044e-19     87     30     49GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; IDA:BHF-UCL.
GO:0003723; F:RNA binding; ISS:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
161P60900    246   PSA6_HUMAN Proteasome subunit alpha type-6 OS...2044e-19     87     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005844; C:polysome; IDA:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL.
GO:0051059; F:NF-kappaB binding; IPI:BHF-UCL.::GO:0035639; F:purine ribonucleoside triphosphate binding; NAS:BHF-UCL.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
162Q2YDE4    246   PSA6_BOVIN Proteasome subunit alpha type-6 OS...2044e-19     87     30     49
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
163Q9QUM9    246   PSA6_MOUSE Proteasome subunit alpha type-6 OS...2048e-19     86.3     30     49GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL.
GO:0003723; F:RNA binding; IDA:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0007519; P:skeletal muscle tissue development; NAS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
164Q8SQS5    239   PSA1_ENCCU Probable proteasome subunit alpha ...2063e-18     84.3     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
165Q9V5C6    253   PSA3_DROME Proteasome subunit alpha type-3 OS...2213e-18     84.3     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
166P90513    252   PSA3_ACACA Proteasome subunit alpha type-3 OS...1758e-18     83.2     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
167O94517    244   PSA6_SCHPO Probable proteasome subunit alpha ...2363e-17     81.6     26     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
168Q27563    248   PSA3_DICDI Proteasome subunit alpha type-3 OS...1722e-16     79.3     29     49GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
169Q9XZJ4    244   PSA6_DROME Proteasome subunit alpha type-6 OS...2383e-16     78.6     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
170Q09583    250   PSA3_CAEEL Proteasome subunit alpha type-3 OS...2200.000000000000001     76.6     26     48GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
171O17586    246   PSA6_CAEEL Proteasome subunit alpha type-6 OS...2250.00000000000001     73.9     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
172O59770    253   PSA3_SCHPO Probable proteasome subunit alpha ...1690.00000000000005     72     30     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
173A2BN27    212   PSB2_HYPBU Proteasome subunit beta 2 OS=Hyper...1970.0000000000007     68.6     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
174Q8SRU3    232   PSA5_ENCCU Probable proteasome subunit alpha ...1790.000000000001     67.8     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
175B5IEE5    210   PSB_ACIB4 Proteasome subunit beta OS=Acidulip...1720.00000000001     64.7     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
176A8AB58    212   PSB2_IGNH4 Proteasome subunit beta 2 OS=Ignic...1920.00000000004     63.5     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
177Q8TW10    210   PSB_METKA Proteasome subunit beta OS=100938)....2120.00000000005     63.2     23     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
178P21243    252   PSA6_YEAST Proteasome component C7-alpha OS=S...2260.00000000006     63.5     26     43GO:0005739; C:mitochondrion; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IC:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
179Q9YER0    219   PSB2_AERPE Proteasome subunit beta 2 OS=10013...1920.000000001     59.3     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
180Q8ZST5    203   PSB2_PYRAE Proteasome subunit beta 2 OS=/ NBR...1980.000000002     58.9     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
181Q9GU37    266   PSA1_TRYBB Proteasome subunit alpha type-1 OS...1830.000000002     59.7     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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