UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR300C

Length:

510

Number of sequences:

5887

Description:

YMR300C ADE4 SGDID:S000004915, Chr XIII from 867091-865559, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P04046	510	PUR1_YEAST Amidophosphoribosyltransferase OS=...	510	0	1055	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0004044; F:amidophosphoribosyltransferase activity; IMP:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006189; P:'de novo' IMP biosynthetic process; IMP:SGD.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.
2	Q12698	510	PUR1_LACKL Amidophosphoribosyltransferase OS=...	510	0	890	83	91
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
3	P41390	533	PUR1_SCHPO Amidophosphoribosyltransferase OS=...	526	0	605	57	71	GO:0005737; C:cytoplasm; IDA:PomBase.
									GO:0004044; F:amidophosphoribosyltransferase activity; TAS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006189; P:'de novo' IMP biosynthetic process; ISS:PomBase.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IC:PomBase.
4	Q51342	501	PUR1_PSEAE Amidophosphoribosyltransferase OS=...	509	0	526	53	68
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
5	Q9L6B8	504	PUR1_PASMU Amidophosphoribosyltransferase OS=...	502	4e-172	502	51	67
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
6	P0AG17	505	PUR1_SHIFL Amidophosphoribosyltransferase OS=...	489	4e-170	497	52	67
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
7	P0AG16	505	PUR1_ECOLI Amidophosphoribosyltransferase OS=...	489	4e-170	497	52	67	GO:0005829; C:cytosol; IDA:UniProtKB.
									GO:0004044; F:amidophosphoribosyltransferase activity; IDA:EcoliWiki.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IDA:EcoliWiki.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IDA:EcoliWiki.
8	P43854	505	PUR1_HAEIN Amidophosphoribosyltransferase OS=...	511	2e-167	490	50	66
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
9	Q57657	471	PUR1_METJA Probable amidophosphoribosyltransf...	466	3e-94	301	40	56
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
10	O29388	457	PUR1_ARCFU Probable amidophosphoribosyltransf...	456	4e-92	295	41	57
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
11	O26742	474	PUR1_METTH Amidophosphoribosyltransferase OS=...	477	5e-90	290	36	58
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
12	O57979	449	PUR1_PYRHO Amidophosphoribosyltransferase OS=...	470	1e-84	275	39	55
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
13	Q55038	493	PUR1_SYNE7 Amidophosphoribosyltransferase OS=...	457	1e-83	274	36	54
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
14	Q55621	495	PUR1_SYNY3 Amidophosphoribosyltransferase OS=...	479	1e-83	274	37	53
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
15	Q9V253	447	PUR1_PYRAB Amidophosphoribosyltransferase OS=...	473	9e-80	262	38	53
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
16	P52418	569	PUR1_SOYBN Amidophosphoribosyltransferase, ch...	501	5e-79	264	35	51	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
17	Q8CT30	494	PUR1_STAES Amidophosphoribosyltransferase OS=...	509	5e-75	251	34	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
18	Q5HQA0	494	PUR1_STAEQ Amidophosphoribosyltransferase OS=...	509	5e-75	251	34	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
19	P00497	476	PUR1_BACSU Amidophosphoribosyltransferase OS=...	482	2e-74	249	36	53
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
20	P52419	485	PUR1_VIGAC Amidophosphoribosyltransferase, ch...	477	5e-73	246	36	51	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
21	Q86A85	521	PUR1_DICDI Amidophosphoribosyltransferase OS=...	468	8e-73	246	36	51	GO:0005737; C:cytoplasm; ISS:dictyBase.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; ISS:UniProtKB.
22	P99164	494	PUR1_STAAN Amidophosphoribosyltransferase OS=...	483	4e-71	241	35	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
23	P65831	494	PUR1_STAAM Amidophosphoribosyltransferase OS=...	483	4e-71	241	35	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
24	Q8NX91	494	PUR1_STAAW Amidophosphoribosyltransferase OS=...	483	4e-71	241	35	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
25	Q6GAE3	494	PUR1_STAAS Amidophosphoribosyltransferase OS=...	483	4e-71	241	35	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
26	Q5HH14	494	PUR1_STAAC Amidophosphoribosyltransferase OS=...	483	4e-71	241	35	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
27	P28173	510	PUR1_CHICK Amidophosphoribosyltransferase OS=...	481	1e-69	238	36	51	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006189; P:'de novo' IMP biosynthetic process; TAS:Reactome.::GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.
28	Q6GI14	494	PUR1_STAAR Amidophosphoribosyltransferase OS=...	483	4e-69	235	34	52
									GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
29	Q06203	517	PUR1_HUMAN Amidophosphoribosyltransferase OS=...	503	5e-69	236	33	50	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
30	P35433	517	PUR1_RAT Amidophosphoribosyltransferase OS=Ra...	478	3e-67	231	33	51	GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0035690; P:cellular response to drug; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0000082; P:G1/S transition of mitotic cell cycle; IEP:RGD.::GO:0006543; P:glutamine catabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0007595; P:lactation; IEP:RGD.::GO:0060135; P:maternal process involved in female pregnancy; IEP:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IDA:RGD.::GO:0019693; P:ribose phosphate metabolic process; IDA:RGD.
31	Q50028	556	PUR1_MYCLE Amidophosphoribosyltransferase OS=...	461	3e-67	232	35	52
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004044; F:amidophosphoribosyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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