Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR296C
Length:
558
Number of sequences:
5887
Description:
YMR296C LCB1 SGDID:S000004911, Chr XIII from 860891-859215, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P25045    558   LCB1_YEAST Serine palmitoyltransferase 1 OS=S...5580     1160     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IPI:SGD.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IMP:SGD.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD.
2O59682    509   LCB1_SCHPO Serine palmitoyltransferase 1 OS=S...5235e-92     298     34     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:PomBase.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; ISS:PomBase.
3Q55FL5    479   SPTC1_DICDI Serine palmitoyltransferase 1 OS=...4871e-91     296     37     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
4O35704    473   SPTC1_MOUSE Serine palmitoyltransferase 1 OS=...5163e-85     279     34     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0046511; P:sphinganine biosynthetic process; IMP:MGI.::GO:0006686; P:sphingomyelin biosynthetic process; IMP:MGI.::GO:0046512; P:sphingosine biosynthetic process; IMP:MGI.
5O54695    473   SPTC1_CRIGR Serine palmitoyltransferase 1 OS=...5165e-83     273     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006686; P:sphingomyelin biosynthetic process; IDA:MGI.
6O15269    473   SPTC1_HUMAN Serine palmitoyltransferase 1 OS=...4672e-81     269     34     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
7Q5R9T5    473   SPTC1_PONAB Serine palmitoyltransferase 1 OS=...4672e-81     269     34     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
8Q60HD1    473   SPTC1_MACFA Serine palmitoyltransferase 1 OS=...4673e-81     268     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
9Q3MHG1    473   SPTC1_BOVIN Serine palmitoyltransferase 1 OS=...4512e-75     253     33     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
10A9BGL0    393   BIKB_PETMO Putative 8-amino-7-oxononanoate sy...2672e-41     158     32     53
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
11B0K590    395   BIKB_THEPX Putative 8-amino-7-oxononanoate sy...2673e-41     157     33     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
12A7HMM1    395   BIKB_FERNB Putative 8-amino-7-oxononanoate sy...2693e-41     157     30     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
13B0KC20    395   BIKB_THEP3 Putative 8-amino-7-oxononanoate sy...2663e-41     157     33     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
14B7ID58    391   BIKB_THEAB Putative 8-amino-7-oxononanoate sy...2902e-39     152     30     50
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
15A6TU88    395   BIKB_ALKMQ Putative 8-amino-7-oxononanoate sy...2697e-39     150     33     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
16A6LMP4    391   BIKB_THEM4 Putative 8-amino-7-oxononanoate sy...2682e-38     149     30     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
17Q749W3    391   BIOF_GEOSL 8-amino-7-oxononanoate synthase OS...2451e-36     144     35     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
18B5Y9Z4    393   BIKB_COPPD Putative 8-amino-7-oxononanoate sy...2672e-36     144     30     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
19Q65ML1    379   BIOF_BACLD Putative 8-amino-7-oxononanoate sy...2663e-36     143     30     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
20Q635G4    395   BIOF_BACCZ Putative 8-amino-7-oxononanoate sy...2673e-35     140     30     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
21Q58694    372   BIOF_METJA Putative 8-amino-7-oxononanoate sy...2924e-35     139     32     53
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
22Q67N86    392   BIKB_SYMTH Putative 8-amino-7-oxononanoate sy...2675e-35     139     28     50
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
23A8MEX7    395   BIKB_ALKOO Putative 8-amino-7-oxononanoate sy...2455e-35     139     32     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
24Q8EM07    396   PPAT_OCEIH Putative pyridoxal phosphate-depen...2602e-34     138     30     51
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
25B7JLX2    395   BIOF_BACC0 Putative 8-amino-7-oxononanoate sy...2672e-34     137     30     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
26Q81MB0    395   BIOF_BACAN Putative 8-amino-7-oxononanoate sy...2672e-34     137     30     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
27Q6HE48    395   BIOF_BACHK Putative 8-amino-7-oxononanoate sy...2672e-34     137     30     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
28Q731H9    395   BIOF_BACC1 Putative 8-amino-7-oxononanoate sy...2693e-34     137     31     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
29A0RIB9    395   BIOF_BACAH Putative 8-amino-7-oxononanoate sy...2674e-34     137     30     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
30O15270    562   SPTC2_HUMAN Serine palmitoyltransferase 2 OS=...2904e-34     139     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
31Q9NUV7    552   SPTC3_HUMAN Serine palmitoyltransferase 3 OS=...2785e-34     139     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0046520; P:sphingoid biosynthetic process; IDA:MGI.
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