UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR296C

Length:

558

Number of sequences:

5887

Description:

YMR296C LCB1 SGDID:S000004911, Chr XIII from 860891-859215, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	B8J3V0	384	BIOF_DESDA Putative 8-amino-7-oxononanoate sy...	228	6e-31	127	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
62	Q39XE0	396	BIOF_GEOMG 8-amino-7-oxononanoate synthase OS...	261	1e-30	127	30	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
63	A7GSE1	395	BIOF_BACCN Putative 8-amino-7-oxononanoate sy...	243	1e-30	127	30	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
64	A7Z5B4	386	BIOF_BACA2 Putative 8-amino-7-oxononanoate sy...	314	1e-30	126	25	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
65	A8FDG9	392	BIKB_BACP2 Putative 8-amino-7-oxononanoate sy...	268	1e-30	126	26	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
66	A5G6I9	391	BIOF_GEOUR 8-amino-7-oxononanoate synthase OS...	259	3e-30	125	31	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
67	O88986	416	KBL_MOUSE 2-amino-3-ketobutyrate coenzyme A l...	271	4e-30	125	31	49	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
68	Q54EX5	490	SPTC2_DICDI Serine palmitoyltransferase 2 OS=...	283	6e-30	126	30	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
69	P48241	562	LCB2_KLULA Serine palmitoyltransferase 2 OS=1...	273	7e-30	127	28	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
70	Q7NNL4	388	BIOF_GLOVI Putative 8-amino-7-oxononanoate sy...	239	2e-29	123	30	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
71	O31777	392	BIKB_BACSU Putative 8-amino-7-oxononanoate sy...	281	3e-29	122	26	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
72	Q09925	603	LCB2_SCHPO Serine palmitoyltransferase 2 OS=S...	273	5e-29	124	26	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:PomBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:PomBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:PomBase.
73	Q47C04	387	BIOF_DECAR 8-amino-7-oxononanoate synthase OS...	285	6e-29	122	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
74	Q9K625	395	BIOF_BACHD Putative 8-amino-7-oxononanoate sy...	291	7e-29	122	30	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
75	O75600	419	KBL_HUMAN 2-amino-3-ketobutyrate coenzyme A l...	271	1e-28	121	30	49	GO:0005739; C:mitochondrion; NAS:UniProtKB.
									GO:0008890; F:glycine C-acetyltransferase activity; NAS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; NAS:UniProtKB.
76	P40970	561	LCB2_YEAST Serine palmitoyltransferase 2 OS=S...	244	1e-28	123	28	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IPI:SGD.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IMP:SGD.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD.
77	O66875	373	BIOF_AQUAE Putative 8-amino-7-oxononanoate sy...	275	2e-28	120	27	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
78	A6UQL9	370	BIOF_METVS Putative 8-amino-7-oxononanoate sy...	290	4e-28	119	28	52
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
79	B1YMC6	390	BIKB_EXIS2 Putative 8-amino-7-oxononanoate sy...	289	5e-28	119	26	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
80	Q81I05	396	PPAT_BACCR Putative pyridoxal phosphate-depen...	259	6e-28	119	28	49
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
81	B7GHW7	390	BIOF_ANOFW Putative 8-amino-7-oxononanoate sy...	272	8e-28	119	28	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
82	B5YFU5	388	BIOF_THEYD Putative 8-amino-7-oxononanoate sy...	266	8e-28	118	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
83	Q81V80	396	PPAT_BACAN Putative pyridoxal phosphate-depen...	259	1e-27	118	28	49
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
84	Q3J9D6	377	BIOF_NITOC 8-amino-7-oxononanoate synthase OS...	278	1e-27	117	27	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
85	B9M8U3	393	BIOF_GEOSF 8-amino-7-oxononanoate synthase OS...	264	2e-27	117	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
86	Q0BUV6	382	BIKB_GRABC Putative 8-amino-7-oxononanoate sy...	276	3e-27	117	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
87	Q609V1	387	BIOF_METCA 8-amino-7-oxononanoate synthase OS...	243	6e-27	116	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
88	B1XL23	395	BIOF_SYNP2 Putative 8-amino-7-oxononanoate sy...	259	9e-27	115	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
89	A4G5N9	388	BIOF_HERAR 8-amino-7-oxononanoate synthase OS...	291	1e-26	115	28	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
90	Q3M9A4	386	BIOF_ANAVT Putative 8-amino-7-oxononanoate sy...	221	2e-26	114	32	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
91	P74770	393	BIOF_SYNY3 Putative 8-amino-7-oxononanoate sy...	243	3e-26	114	27	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.

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