UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR296C

Length:

558

Number of sequences:

5887

Description:

YMR296C LCB1 SGDID:S000004911, Chr XIII from 860891-859215, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q9NUV7	552	SPTC3_HUMAN Serine palmitoyltransferase 3 OS=...	278	5e-34	139	28	52	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0046520; P:sphingoid biosynthetic process; IDA:MGI.
32	Q5KY23	390	BIOF_GEOKA Putative 8-amino-7-oxononanoate sy...	275	6e-34	136	28	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
33	B0C205	394	BIOF_ACAM1 Putative 8-amino-7-oxononanoate sy...	312	6e-34	136	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
34	Q73KM3	395	BIKB_TREDE Putative 8-amino-7-oxononanoate sy...	284	1e-33	135	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
35	Q8NXY3	395	PPAT_STAAW Putative pyridoxal phosphate-depen...	259	1e-33	135	31	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
36	Q6GBT7	395	PPAT_STAAS Putative pyridoxal phosphate-depen...	259	1e-33	135	31	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
37	P60120	395	PPAT_STAAN Putative pyridoxal phosphate-depen...	259	1e-33	135	31	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
38	P60121	395	PPAT_STAAM Putative pyridoxal phosphate-depen...	259	1e-33	135	31	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
39	Q5HIC5	395	PPAT_STAAC Putative pyridoxal phosphate-depen...	259	2e-33	135	31	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
40	O54694	560	SPTC2_CRIGR Serine palmitoyltransferase 2 OS=...	290	2e-33	137	29	50	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
41	P97363	560	SPTC2_MOUSE Serine palmitoyltransferase 2 OS=...	290	3e-33	136	29	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:MGI.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0046511; P:sphinganine biosynthetic process; IDA:MGI.::GO:0006686; P:sphingomyelin biosynthetic process; IMP:MGI.::GO:0046512; P:sphingosine biosynthetic process; IMP:MGI.
42	B7IWN1	395	BIOF_BACC2 Putative 8-amino-7-oxononanoate sy...	267	7e-33	133	30	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
43	Q818X0	395	BIOF_BACCR Putative 8-amino-7-oxononanoate sy...	267	1e-32	132	30	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
44	B7HAZ0	395	BIOF_BACC4 Putative 8-amino-7-oxononanoate sy...	267	1e-32	132	30	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
45	Q0P5L8	419	KBL_BOVIN 2-amino-3-ketobutyrate coenzyme A l...	269	1e-32	133	31	50	GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.
									GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
46	A6UWX3	381	BIOF_META3 Putative 8-amino-7-oxononanoate sy...	257	2e-32	132	31	55
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
47	B9IWY0	394	BIOF_BACCQ Putative 8-amino-7-oxononanoate sy...	269	2e-32	132	31	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
48	B7HNN4	394	BIOF_BACC7 Putative 8-amino-7-oxononanoate sy...	269	2e-32	132	31	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
49	Q6GJB8	395	PPAT_STAAR Putative pyridoxal phosphate-depen...	259	3e-32	131	31	49
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
50	P22806	389	BIOF_LYSSH 8-amino-7-oxononanoate synthase OS...	272	3e-32	131	29	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
51	A9VG56	395	BIOF_BACWK Putative 8-amino-7-oxononanoate sy...	267	3e-32	131	30	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
52	B5ELF7	389	BIOF_ACIF5 8-amino-7-oxononanoate synthase OS...	238	4e-32	131	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
53	B7J3Y7	389	BIOF_ACIF2 8-amino-7-oxononanoate synthase OS...	238	4e-32	131	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
54	P53556	389	BIOF_BACSU 8-amino-7-oxononanoate synthase OS...	263	6e-32	130	28	53
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
55	Q3A3Z8	390	BIOF_PELCD Putative 8-amino-7-oxononanoate sy...	282	9e-32	130	31	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
56	B5EEV8	389	BIOF_GEOBB 8-amino-7-oxononanoate synthase OS...	261	2e-31	129	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
57	Q8KZM9	371	BIOF_BACNA Putative 8-amino-7-oxononanoate sy...	259	3e-31	128	31	53
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
58	A7Z4X1	391	BIKB_BACA2 Putative 8-amino-7-oxononanoate sy...	278	4e-31	128	27	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
59	Q8BG54	563	SPTC3_MOUSE Serine palmitoyltransferase 3 OS=...	325	5e-31	130	27	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
60	A3DBD5	388	BIOF_CLOTH Putative 8-amino-7-oxononanoate sy...	275	6e-31	127	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
61	B8J3V0	384	BIOF_DESDA Putative 8-amino-7-oxononanoate sy...	228	6e-31	127	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.

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