UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR296C

Length:

558

Number of sequences:

5887

Description:

YMR296C LCB1 SGDID:S000004911, Chr XIII from 860891-859215, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	Q7N6Q6	383	BIOF_PHOLL 8-amino-7-oxononanoate synthase OS...	268	2e-20	97.1	26	43
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
182	Q92G23	414	HEM1_RICCN 5-aminolevulinate synthase OS=Rick...	275	2e-20	97.4	25	46
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
183	Q8YZT3	386	BIOF_NOSS1 Putative 8-amino-7-oxononanoate sy...	221	2e-20	97.1	32	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
184	P43090	582	HEM0_OPSTA 5-aminolevulinate synthase, erythr...	256	2e-20	98.6	27	45	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
185	A6UYW1	401	BIOF_PSEA7 8-amino-7-oxononanoate synthase OS...	369	2e-20	97.1	24	41
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
186	Q4ZMA9	396	BIOF_PSEU2 8-amino-7-oxononanoate synthase OS...	265	4e-20	96.3	25	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
187	Q9XS79	640	HEM1_DELLE 5-aminolevulinate synthase, nonspe...	265	4e-20	97.8	27	43	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
188	B5EUP9	383	BIOF_VIBFM 8-amino-7-oxononanoate synthase OS...	219	4e-20	95.9	27	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
189	Q6BX71	575	HEM1_DEBHA 5-aminolevulinate synthase, mitoch...	270	4e-20	97.8	24	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
190	Q9ZCB8	414	HEM1_RICPR 5-aminolevulinate synthase OS=Rick...	274	5e-20	95.9	25	47
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
191	B0KJ54	390	BIOF_PSEPG 8-amino-7-oxononanoate synthase OS...	254	6e-20	95.5	27	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
192	Q7RVY5	629	HEM1_NEUCR 5-aminolevulinate synthase, mitoch...	305	6e-20	97.4	24	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
193	Q9KSZ3	384	BIOF_VIBCH 8-amino-7-oxononanoate synthase OS...	271	8e-20	95.1	26	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
194	A5FZN8	381	BIOF_ACICJ Putative 8-amino-7-oxononanoate sy...	267	9e-20	94.7	25	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
195	A6W0Y0	403	BIOF_MARMS 8-amino-7-oxononanoate synthase OS...	237	1e-19	95.1	27	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
196	Q88A97	396	BIOF_PSESM 8-amino-7-oxononanoate synthase OS...	256	1e-19	94.7	26	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
197	Q6FXE3	530	HEM1_CANGA 5-aminolevulinate synthase, mitoch...	297	1e-19	95.9	24	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
198	C4LK80	720	BIOWF_CORK4 Biotin biosynthesis bifunctional ...	303	1e-19	96.3	26	42
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
199	Q740R7	381	BIKB_MYCPA Putative 8-amino-7-oxononanoate sy...	262	2e-19	94	27	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
200	Q68VS3	414	HEM1_RICTY 5-aminolevulinate synthase OS=Rick...	274	2e-19	94.4	25	46
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
201	A4XZR8	389	BIOF_PSEMY 8-amino-7-oxononanoate synthase OS...	265	2e-19	94	27	44
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
202	Q88QX1	390	BIOF_PSEPK 8-amino-7-oxononanoate synthase OS...	252	2e-19	93.6	25	44
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
203	Q6A6M4	653	BIOWF_PROAC Biotin biosynthesis bifunctional ...	238	2e-19	95.5	23	47
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
204	P38092	648	HEM1_EMENI 5-aminolevulinate synthase, mitoch...	314	2e-19	95.5	25	43	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
205	Q75DX7	556	HEM1_ASHGO 5-aminolevulinate synthase, mitoch...	257	3e-19	95.1	26	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
206	P08680	587	HEM0_MOUSE 5-aminolevulinate synthase, erythr...	254	3e-19	95.1	27	46	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
207	Q6D3C0	385	BIOF_ERWCT 8-amino-7-oxononanoate synthase OS...	187	4e-19	93.2	33	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
208	P08080	404	HEM1_RHIME 5-aminolevulinate synthase OS=meli...	239	4e-19	93.2	26	45
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
209	D4H9Y2	668	BIOWF_PROAS Biotin biosynthesis bifunctional ...	237	6e-19	94	23	47
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
210	Q5R557	587	HEM0_PONAB 5-aminolevulinate synthase, erythr...	254	8e-19	93.6	26	44	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
211	O94069	564	HEM1_CANAL 5-aminolevulinate synthase, mitoch...	266	8e-19	93.6	23	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IMP:CGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IMP:CGD.

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