Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR291W
Length:
586
Number of sequences:
5887
Description:
YMR291W TDA1 SGDID:S000004905, Chr XIII from 852630-854390, Genome Release 64-1-1, Verified ORF, "Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931A8XJL7    472   SAX1_CAEBR Serine/threonine-protein kinase sa...2630.000000000002     73.2     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
932P42685    505   FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo...2620.000000000002     73.6     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
933Q75LR7    342   SAPK1_ORYSJ Serine/threonine-protein kinase S...3660.000000000002     72.4     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
934Q75H77    362   SAPKA_ORYSJ Serine/threonine-protein kinase S...3130.000000000002     72.4     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
935A2VDV2    465   STK38_BOVIN Serine/threonine-protein kinase 3...2700.000000000002     73.2     26     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
936P34947    590   GRK5_HUMAN G protein-coupled receptor kinase ...3410.000000000002     73.6     25     41GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005080; F:protein kinase C binding; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
937Q8WXR4    1341   MYO3B_HUMAN Myosin-IIIb OS=Homo sapiens (Huma...2740.000000000002     73.9     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
938Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...2720.000000000002     73.2     25     42GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
939Q8BWW9    983   PKN2_MOUSE Serine/threonine-protein kinase N2...3540.000000000002     73.9     27     44GO:0043296; C:apical junction complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
940Q9W0V1    836   PDPK1_DROME 3-phosphoinositide-dependent prot...3590.000000000002     73.9     23     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0006916; P:anti-apoptosis; IMP:FlyBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007292; P:female gamete generation; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0046620; P:regulation of organ growth; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0007548; P:sex differentiation; TAS:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:UniProtKB.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.
941Q5QN75    355   M2K1_ORYSJ Mitogen-activated protein kinase k...3140.000000000002     72.4     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
942Q5R8M1    465   STK38_PONAB Serine/threonine-protein kinase 3...2700.000000000002     73.2     26     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
943Q15208    465   STK38_HUMAN Serine/threonine-protein kinase 3...2700.000000000002     73.2     26     41GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0070688; C:MLL5-L complex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
944Q9QY78    757   IKKB_RAT Inhibitor of nuclear factor kappa-B ...1880.000000000002     73.6     29     44GO:0008385; C:IkappaB kinase complex; IDA:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD.
945Q91VJ4    465   STK38_MOUSE Serine/threonine-protein kinase 3...2700.000000000002     73.2     26     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
946P51817    358   PRKX_HUMAN cAMP-dependent protein kinase cata...2490.000000000002     72.4     25     42GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0043542; P:endothelial cell migration; IMP:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; IDA:UniProtKB.::GO:0060993; P:kidney morphogenesis; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; IDA:UniProtKB.
947Q9JJX8    414   ST32B_MOUSE Serine/threonine-protein kinase 3...2630.000000000002     72.8     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
948O14328    474   KSP1_SCHPO Serine/threonine-protein kinase ks...2920.000000000002     72.8     26     39GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
949O94235    678   MPH1_SCHPO Serine/threonine-protein kinase mp...2900.000000000003     73.2     25     41GO:0000778; C:condensed nuclear chromosome kinetochore; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
950A7F0W2    951   ATG1_SCLS1 Serine/threonine-protein kinase AT...2970.000000000003     73.6     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
951O43930    277   PRKY_HUMAN Serine/threonine-protein kinase PR...2730.000000000003     70.9     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
952Q86UX6    486   ST32C_HUMAN Serine/threonine-protein kinase 3...2560.000000000003     72.8     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
953O74426    338   PPK33_SCHPO Serine/threonine-protein kinase p...2560.000000000003     71.6     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
954Q09690    1087   POM1_SCHPO Dual specificity protein kinase po...2610.000000000003     73.6     25     43GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
GO:0070650; P:actin filament bundle distribution; TAS:PomBase.::GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; IMP:PomBase.::GO:0071343; P:negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis; TAS:PomBase.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0071574; P:protein localization to medial cortex; IMP:PomBase.::GO:0008361; P:regulation of cell size; IGI:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0007165; P:signal transduction; IDA:PomBase.
955P35761    856   TTK_MOUSE Dual specificity protein kinase TTK...3380.000000000003     73.2     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
956Q9SMQ4    350   SRK2F_ARATH Serine/threonine-protein kinase S...3130.000000000003     71.6     26     42GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
957Q52EB3    982   ATG1_MAGO7 Serine/threonine-protein kinase AT...2730.000000000003     73.2     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:PAMGO_MGG.
GO:0048102; P:autophagic cell death; IMP:PAMGO_MGG.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0044409; P:entry into host; IMP:PAMGO_MGG.::GO:0009405; P:pathogenesis; IMP:PAMGO_MGG.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0009847; P:spore germination; IMP:PAMGO_MGG.
958P06803    397   PIM1_MOUSE Serine/threonine-protein kinase pi...3140.000000000003     72     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.
959Q03043    1088   KGP24_DROME cGMP-dependent protein kinase, is...1910.000000000003     73.2     27     44GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.
GO:0046959; P:habituation; IMP:FlyBase.::GO:0030536; P:larval feeding behavior; IMP:UniProtKB.::GO:0008345; P:larval locomotory behavior; IMP:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008016; P:regulation of heart contraction; IMP:FlyBase.::GO:0032095; P:regulation of response to food; IMP:FlyBase.::GO:0009744; P:response to sucrose stimulus; IDA:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.
960Q9R0G8    1455   NRK_MOUSE Nik-related protein kinase OS=Mus m...3530.000000000004     73.2     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007256; P:activation of JNKK activity; IDA:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007567; P:parturition; IMP:MGI.::GO:0060721; P:regulation of spongiotrophoblast cell proliferation; IMP:MGI.
961P38147    527   CHK1_YEAST Serine/threonine-protein kinase CH...3210.000000000004     72.4     24     46GO:0005634; C:nucleus; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.
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