Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR276W
Length:
373
Number of sequences:
5887
Description:
YMR276W DSK2 SGDID:S000004889, Chr XIII from 818827-819948, Genome Release 64-1-1, Verified ORF, "Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P48510    373   DSK2_YEAST Ubiquitin domain-containing protei...3730     752     100     100GO:0005635; C:nuclear envelope; IGI:GOC.
GO:0030674; F:protein binding, bridging; IMP:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0007103; P:spindle pole body duplication in nuclear envelope; IGI:SGD.
2Q10169    354   DSK2_SCHPO Deubiquitination-protection protei...3765e-72     234     44     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0031593; F:polyubiquitin binding; IDA:PomBase.
GO:0033554; P:cellular response to stress; NAS:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0042177; P:negative regulation of protein catabolic process; IMP:PomBase.::GO:0030474; P:spindle pole body duplication; ISS:PomBase.
3Q8R317    582   UBQL1_MOUSE Ubiquilin-1 OS=Mus musculus (Mous...2280.00001     50.8     30     43GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019215; F:intermediate filament binding; NAS:UniProtKB.::GO:0019900; F:kinase binding; ISS:UniProtKB.::GO:0005102; F:receptor binding; NAS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:HGNC.::GO:0031396; P:regulation of protein ubiquitination; ISS:HGNC.::GO:0001666; P:response to hypoxia; ISS:HGNC.
4Q9JJP9    582   UBQL1_RAT Ubiquilin-1 OS=Rattus norvegicus (R...3020.000003     52.8     27     42GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0006915; P:apoptotic process; ISS:HGNC.::GO:0031396; P:regulation of protein ubiquitination; ISS:HGNC.::GO:0001666; P:response to hypoxia; ISS:HGNC.
5Q99NB8    596   UBQL4_MOUSE Ubiquilin-4 OS=Mus musculus (Mous...420.0003     46.2     45     67GO:0005829; C:cytosol; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.
GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
6Q9UHD9    624   UBQL2_HUMAN Ubiquilin-2 OS=Homo sapiens (Huma...420.0006     45.4     45     67GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0008219; P:cell death; IEA:UniProtKB-KW.
7Q9UMX0    589   UBQL1_HUMAN Ubiquilin-1 OS=Homo sapiens (Huma...2500.000002     53.5     28     42GO:0005783; C:endoplasmic reticulum; IDA:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; NAS:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019900; F:kinase binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:HGNC.::GO:0031396; P:regulation of protein ubiquitination; IDA:HGNC.::GO:0001666; P:response to hypoxia; IMP:HGNC.
8Q5R684    589   UBQL1_PONAB Ubiquilin-1 OS=Pongo abelii (Suma...2820.00002     50.1     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
9Q9NIF3    523   UBQL_DICDI Ubiquilin OS=Dictyostelium discoid...600.0002     46.6     38     60GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
10Q8C5U9    658   UBQL3_MOUSE Ubiquilin-3 OS=Mus musculus (Mous...2170.00000000005     67.8     26     47
11P46379    1132   BAG6_HUMAN Large proline-rich protein BAG6 OS...1670.00000000006     67.8     31     50GO:0071818; C:BAT3 complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
12Q9QZM0    638   UBQL2_MOUSE Ubiquilin-2 OS=Mus musculus (Mous...420.0006     45.4     45     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
13O14399    78   UBL1_SCHPO Ubiquitin-like protein 1 OS=Schizo...570.0000000006     60.1     44     67GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0031386; F:protein tag; IDA:PomBase.
GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; NAS:PomBase.::GO:0045116; P:protein neddylation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
14Q9NRR5    601   UBQL4_HUMAN Ubiquilin-4 OS=Homo sapiens (Huma...460.0004     46.2     41     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
15A7X5R6    1088   BAG6_ORNAN Large proline-rich protein BAG6 OS...1480.000000001     63.5     34     51GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
16Q9H347    655   UBQL3_HUMAN Ubiquilin-3 OS=Homo sapiens (Huma...410.2     37.4     41     61
17Q9Z1R2    1154   BAG6_MOUSE Large proline-rich protein BAG6 OS...1480.000000004     62     32     51GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:UniProtKB.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IMP:UniProtKB.::GO:0007420; P:brain development; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; IMP:UniProtKB.::GO:0030324; P:lung development; IMP:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
18Q6MG49    1146   BAG6_RAT Large proline-rich protein BAG6 OS=R...1240.000000004     62     35     54GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IEP:RGD.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
19P0C031    153   RUB2_ORYSJ Ubiquitin-NEDD8-like protein RUB2 ...560.001     42.4     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
20Q9SHE7    156   RUB1_ARATH Ubiquitin-NEDD8-like protein RUB1 ...560.001     42.4     39     57GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0009790; P:embryo development; IGI:TAIR.::GO:0009693; P:ethylene biosynthetic process; IMP:TAIR.::GO:0045116; P:protein neddylation; TAS:TAIR.::GO:0009733; P:response to auxin stimulus; TAS:TAIR.
21P0C030    153   RUB1_ORYSJ Ubiquitin-NEDD8-like protein RUB1 ...560.001     42.4     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
22P0C073    153   RUB1_DESAN Ubiquitin-NEDD8-like protein RUB1 ...560.001     42.4     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
23Q8RUC6    154   RUB2_ARATH Ubiquitin-NEDD8-like protein RUB2 ...560.001     42.4     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
24Q9VJ33    84   NEDD8_DROME NEDD8 OS=Drosophila melanogaster ...570.00000001     56.2     42     61GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031386; F:protein tag; NAS:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045116; P:protein neddylation; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; IMP:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:UniProtKB.::GO:0051438; P:regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0030431; P:sleep; IMP:FlyBase.
25P54728    416   RD23B_MOUSE UV excision repair protein RAD23 ...930.00000002     59.3     32     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; ISS:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:MGI.
26Q29RK4    408   RD23B_BOVIN UV excision repair protein RAD23 ...940.00000002     59.3     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; ISS:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.
27A5D9M6    1128   BAG6_PIG Large proline-rich protein BAG6 OS=S...710.00000003     59.3     41     65GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
28Q05120    93   UBIL_NPVOP Ubiquitin-like protein OS=Orgyia p...560.00000004     55.1     46     63
29Q4KMA2    415   RD23B_RAT UV excision repair protein RAD23 ho...750.00000004     58.2     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; ISS:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.
30P54727    409   RD23B_HUMAN UV excision repair protein RAD23 ...780.00000005     57.8     36     62GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; IDA:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:UniProtKB.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
31Q14DL0    610   UBQLN_MOUSE Ubiquilin-like protein OS=Mus mus...2240.00000007     57.8     25     47
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