UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR272C

Length:

384

Number of sequences:

5887

Description:

YMR272C SCS7 SGDID:S000004885, Chr XIII from 810777-809623, Genome Release 64-1-1, reverse complement, Verified ORF, "Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	P09437	573	CYB2_HANAN Cytochrome b2, mitochondrial OS=Ha...	57	0.0000007	54.7	47	67	GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004460; F:L-lactate dehydrogenase (cytochrome) activity; IEA:EC.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
62	P17571	621	NIA1_MAIZE Nitrate reductase [NADH] OS=Zea ma...	88	0.0000008	54.7	39	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
63	P00175	591	CYB2_YEAST Cytochrome b2, mitochondrial OS=Sa...	52	0.000001	53.9	50	62	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; IDA:SGD.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
									GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004460; F:L-lactate dehydrogenase (cytochrome) activity; IDA:SGD.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006089; P:lactate metabolic process; IMP:SGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
64	Q5UR80	124	CYB5L_MIMIV Cytochrome b5-like protein OS=Aca...	64	0.000003	49.7	41	61	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
65	P16081	916	NIA1_ORYSJ Nitrate reductase [NADH] 1 OS=Oryz...	91	0.000004	52.4	38	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
66	A4FV48	444	FADS2_BOVIN Fatty acid desaturase 2 OS=Bos ta...	94	0.000005	52	32	53	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
67	Q1ZXQ5	459	FAD5C_DICDI Probable Delta(5) fatty acid desa...	85	0.000008	51.2	33	62	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
68	P27967	915	NIA1_HORVU Nitrate reductase [NADH] OS=Hordeu...	80	0.000009	51.6	40	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
69	P27969	912	NIA2_HORVU Nitrate reductase [NADH] OS=Hordeu...	80	0.000009	51.6	40	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
70	Q4R749	444	FADS2_MACFA Fatty acid desaturase 2 OS=Macaca...	54	0.00001	50.8	39	67	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
71	Q9Z0R9	444	FADS2_MOUSE Fatty acid desaturase 2 OS=Mus mu...	94	0.00001	50.4	33	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0004768; F:stearoyl-CoA 9-desaturase activity; IDA:MGI.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
72	P39864	902	NIA_PHYIN Nitrate reductase [NADPH] OS=Phytop...	86	0.00001	50.8	36	53
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0050464; F:nitrate reductase (NADPH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
73	Q9Z122	444	FADS2_RAT Fatty acid desaturase 2 OS=Rattus n...	94	0.00002	50.4	33	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0004768; F:stearoyl-CoA 9-desaturase activity; TAS:RGD.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; TAS:RGD.
74	Q28CZ9	523	NB5R4_XENTR Cytochrome b5 reductase 4 OS=Xeno...	79	0.00002	50.1	32	58	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
									GO:0004128; F:cytochrome-b5 reductase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro.
75	Q0VAX3	487	FS2P1_MOUSE Fatty acid desaturase 2-like prot...	116	0.00002	50.1	31	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
76	O95864	444	FADS2_HUMAN Fatty acid desaturase 2 OS=Homo s...	105	0.00002	50.1	31	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006636; P:unsaturated fatty acid biosynthetic process; TAS:ProtInc.
77	Q5REA7	444	FADS2_PONAB Fatty acid desaturase 2 OS=Pongo ...	105	0.00002	49.7	31	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
78	Q9DEX7	444	FADS2_DANRE Fatty acid desaturase 2 OS=Danio ...	60	0.00006	48.5	37	62	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
79	Q502I6	527	NB5R4_DANRE Cytochrome b5 reductase 4 OS=Dani...	85	0.0001	47.8	29	55	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
									GO:0004128; F:cytochrome-b5 reductase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro.
80	Q7L1T6	521	NB5R4_HUMAN Cytochrome b5 reductase 4 OS=Homo...	117	0.0001	47.8	27	52	GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
									GO:0004128; F:cytochrome-b5 reductase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IDA:UniProtKB.
									GO:0048468; P:cell development; ISS:UniProtKB.::GO:0003032; P:detection of oxygen; NAS:UniProtKB.::GO:0006091; P:generation of precursor metabolites and energy; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0030073; P:insulin secretion; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
81	Q68EJ0	520	NB5R4_RAT Cytochrome b5 reductase 4 OS=Rattus...	79	0.0002	47	29	62	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
									GO:0004128; F:cytochrome-b5 reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.::GO:0020037; F:heme binding; IMP:RGD.::GO:0003958; F:NADPH-hemoprotein reductase activity; IDA:RGD.
									GO:0006739; P:NADP metabolic process; IDA:RGD.
82	Q6DDK2	446	FADS2_XENLA Fatty acid desaturase 2 OS=Xenopu...	61	0.0002	46.6	34	61	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
83	P27968	891	NIA7_HORVU Nitrate reductase [NAD(P)H] OS=Hor...	89	0.0002	47	36	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0050463; F:nitrate reductase [NAD(P)H activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.]
84	Q3TDX8	528	NB5R4_MOUSE Cytochrome b5 reductase 4 OS=Mus ...	79	0.0004	45.8	29	61	GO:0005783; C:endoplasmic reticulum; IDA:MGI.
									GO:0004128; F:cytochrome-b5 reductase activity; IDA:MGI.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0048468; P:cell development; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0046677; P:response to antibiotic; IMP:MGI.
85	Q32LH7	520	NB5R4_BOVIN Cytochrome b5 reductase 4 OS=Bos ...	78	0.0004	45.8	29	60	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
									GO:0004128; F:cytochrome-b5 reductase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro.
86	A4UVI1	444	FADS1_PAPAN Fatty acid desaturase 1 OS=Papio ...	96	0.0005	45.4	30	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
87	Q8X0J4	83	CYB5L_NEUCR Putative cytochrome b5 B11H24.095...	89	0.0006	42.7	34	49
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
88	Q01170	318	NIA_CHLVU Nitrate reductase [NADH] OS=Chlorel...	85	0.0008	44.7	39	49
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
89	Q9Y5Q0	445	FADS3_HUMAN Fatty acid desaturase 3 OS=Homo s...	93	0.0008	44.7	26	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; NAS:UniProtKB.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006636; P:unsaturated fatty acid biosynthetic process; NAS:UniProtKB.
90	A4IFP3	443	FADS3_BOVIN Fatty acid desaturase 3 OS=Bos ta...	81	0.003	43.1	30	51	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
91	Q8K1P9	449	FADS3_RAT Fatty acid desaturase 3 OS=Rattus n...	117	0.003	43.1	25	49	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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