UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR272C

Length:

384

Number of sequences:

5887

Description:

YMR272C SCS7 SGDID:S000004885, Chr XIII from 810777-809623, Genome Release 64-1-1, reverse complement, Verified ORF, "Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q03529	384	SCS7_YEAST Ceramide very long chain fatty aci...	384	0	799	100	100	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0080132; F:fatty acid alpha-hydroxylase activity; IMP:SGD.::GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006674; P:inositol phosphorylceramide metabolic process; IMP:SGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
2	O13846	347	SCS7_SCHPO Ceramide very long chain fatty aci...	351	3e-94	292	43	60	GO:0005789; C:endoplasmic reticulum membrane; IC:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0000170; F:sphingosine hydroxylase activity; ISS:PomBase.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006675; P:mannosyl-inositol phosphorylceramide metabolic process; IMP:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
3	Q2LAM0	372	FA2H_RAT Fatty acid 2-hydroxylase OS=Rattus n...	395	2e-50	179	32	49	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
4	Q5MPP0	372	FA2H_MOUSE Fatty acid 2-hydroxylase OS=Mus mu...	395	6e-49	175	33	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
5	Q4R4P4	372	FA2H_MACFA Fatty acid 2-hydroxylase OS=Macaca...	383	7e-48	172	32	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
6	Q7L5A8	372	FA2H_HUMAN Fatty acid 2-hydroxylase OS=Homo s...	383	1e-47	172	32	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
7	Q9HFV1	131	CYB5_RHIST Cytochrome b5 OS=Rhizopus stolonif...	90	2e-16	79.3	50	66	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
8	O48845	134	CYB52_ARATH Probable cytochrome b5 isoform 2 ...	80	0.0000000000004	70.1	44	68	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
9	P49098	136	CYB5_TOBAC Cytochrome b5 OS=Nicotiana tabacum...	78	0.000000000001	68.6	46	63	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
10	Q9P5L0	139	CYB5_NEUCR Probable cytochrome b5 OS=1257 / F...	78	0.000000000002	68.6	47	64	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
11	Q9V4N3	134	CYB5_DROME Cytochrome b5 OS=Drosophila melano...	96	0.000000000002	68.2	42	61	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0035206; P:regulation of hemocyte proliferation; IMP:FlyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
12	O04354	132	CYB5_BOROF Cytochrome b5 OS=Borago officinali...	78	0.000000000004	67.4	45	64	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
13	P40312	120	CYB5_YEAST Cytochrome b5 OS=Saccharomyces cer...	106	0.00000000002	65.1	38	54	GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:SGD.
									GO:0009055; F:electron carrier activity; IDA:SGD.::GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IDA:SGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
14	Q874I5	129	CYB5_CANTR Cytochrome b5 OS=Candida tropicali...	75	0.00000000002	65.1	44	64	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
15	P11035	917	NIA2_ARATH Nitrate reductase [NADH] 2 OS=Arab...	84	0.00000000003	68.9	46	62	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IDA:TAIR.
									GO:0042128; P:nitrate assimilation; IMP:TAIR.::GO:0006809; P:nitric oxide biosynthetic process; IMP:TAIR.::GO:0009635; P:response to herbicide; IEA:UniProtKB-KW.::GO:0009416; P:response to light stimulus; IMP:TAIR.::GO:0009610; P:response to symbiotic fungus; IEP:TAIR.
16	Q9USM6	129	CYB52_SCHPO Probable cytochrome b5 2 OS=Schiz...	108	0.00000000008	63.5	35	59	GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:PomBase.
									GO:0009055; F:electron carrier activity; ISS:PomBase.::GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
17	Q42342	134	CYB51_ARATH Cytochrome b5 isoform 1 OS=Arabid...	84	0.0000000001	63.2	40	60	GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0005789; C:endoplasmic reticulum membrane; NAS:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
18	P49099	135	CYB5S_TOBAC Cytochrome b5, seed isoform OS=Ni...	78	0.0000000001	63.2	44	60	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
19	P49096	134	CYB5_MUSDO Cytochrome b5 OS=Musca domestica (...	91	0.0000000001	63.2	37	63	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
20	P40934	134	CYB5_BRAOB Cytochrome b5 OS=Brassica oleracea...	73	0.0000000003	62	44	62	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
21	P49100	137	CYB5_ORYSJ Cytochrome b5 OS=Oryza sativa subs...	97	0.0000000004	61.6	36	60	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
22	P04166	146	CYB5B_RAT Cytochrome b5 type B OS=Rattus norv...	73	0.0000000006	61.2	47	64	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IDA:RGD.
									GO:0045153; F:electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity; TAS:RGD.::GO:0008047; F:enzyme activator activity; IDA:RGD.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
23	P39868	911	NIA2_BRANA Nitrate reductase [NADH], clone PB...	149	0.0000000006	64.7	33	50
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
24	P11832	917	NIA1_ARATH Nitrate reductase [NADH] 1 OS=Arab...	82	0.0000000007	64.7	46	61	GO:0005829; C:cytosol; TAS:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0042128; P:nitrate assimilation; IMP:TAIR.::GO:0006809; P:nitric oxide biosynthetic process; IMP:TAIR.::GO:0009635; P:response to herbicide; IEA:UniProtKB-KW.::GO:0009416; P:response to light stimulus; IMP:TAIR.
25	Q9Y1W0	464	FAD5A_DICDI Delta(5) fatty acid desaturase A ...	86	0.0000000007	63.9	41	62	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IC:dictyBase.
									GO:0020037; F:heme binding; IEA:InterPro.::GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IMP:dictyBase.::GO:0009408; P:response to heat; IMP:dictyBase.::GO:0006636; P:unsaturated fatty acid biosynthetic process; IDA:dictyBase.
26	P00171	134	CYB5_BOVIN Cytochrome b5 OS=Bos taurus (Bovin...	95	0.000000001	60.1	36	59	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
27	Q9CQX2	146	CYB5B_MOUSE Cytochrome b5 type B OS=Mus muscu...	73	0.000000001	60.5	45	64	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
28	O94391	124	CYB51_SCHPO Probable cytochrome b5 1 OS=Schiz...	78	0.000000001	59.7	38	64	GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; ISS:PomBase.::GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
29	P39867	911	NIA1_BRANA Nitrate reductase [NADH], clone PB...	82	0.000000002	63.2	45	60
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
30	P39870	890	NIA2_SOYBN Inducible nitrate reductase [NADH]...	88	0.000000002	62.8	44	57
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030151; F:molybdenum ion binding; IEA:InterPro.::GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.::GO:0009703; F:nitrate reductase (NADH) activity; IEA:EC.
									GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
31	P00172	134	CYB5_PIG Cytochrome b5 OS=Sus scrofa (Pig). G...	95	0.000000002	59.3	35	59	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0020037; F:heme binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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