Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR247C
Length:
1562
Number of sequences:
5887
Description:
YMR247C RKR1 SGDID:S000004861, Chr XIII from 768039-763351, Genome Release 64-1-1, reverse complement, Verified ORF, "RING domain E3 ubiquitin ligase; involved in the ubiquitin-mediated degradation of non-stop proteins; functional connections to chromatin modification; nuclear protein that also co-localizes with ribosomes; homolog of mouse Listerin, whose mutation has been reported to cause neurodegeneration in mice"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q8LDB8    381   RING2_ARATH E3 ubiquitin-protein ligase At1g6...521.8     36.6     38     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
182O82353    214   ATL67_ARATH RING-H2 finger protein ATL67 OS=A...362     35.8     42     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
183Q803I4    336   RING2_DANRE E3 ubiquitin-protein ligase RING2...1112     36.2     25     42GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
184P0CH01    372   AT21A_ARATH Putative RING-H2 finger protein A...852.1     36.2     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
185Q8GUU2    359   RIE1_ARATH E3 ubiquitin protein ligase RIE1 O...582.1     36.2     36     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009790; P:embryo development; IMP:UniProtKB.
186Q9FG21    197   ATL71_ARATH Putative RING-H2 finger protein A...492.1     35.4     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
187Q95K04    376   RN133_MACFA E3 ubiquitin-protein ligase RNF13...552.2     36.2     36     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
188Q95QN6    590   YQOE_CAEEL Uncharacterized RING finger protei...482.3     36.6     35     50
GO:0008270; F:zinc ion binding; IEA:InterPro.
189Q28EX7    246   MARH2_XENTR E3 ubiquitin-protein ligase MARCH...552.6     35.8     33     42GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
190Q5PQ35    246   MARH2_XENLA E3 ubiquitin-protein ligase MARCH...552.6     35.8     33     42GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
191Q8N7C7    305   RN148_HUMAN RING finger protein 148 OS=Homo s...552.9     35.8     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
192Q9WTZ1    113   RBX2_MOUSE RING-box protein 2 OS=Mus musculus...333.1     33.9     36     55GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:MGI.::GO:0045116; P:protein neddylation; ISS:UniProtKB.
193Q9UBF6    113   RBX2_HUMAN RING-box protein 2 OS=Homo sapiens...333.1     33.9     36     55GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005507; F:copper ion binding; TAS:ProtInc.::GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; TAS:ProtInc.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0051775; P:response to redox state; TAS:ProtInc.
194Q9SRM0    158   ATL66_ARATH RING-H2 finger protein ATL66 OS=A...343.2     34.7     35     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
195Q99496    336   RING2_HUMAN E3 ubiquitin-protein ligase RING2...1113.7     35.4     24     41GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
196Q9CQJ4    336   RING2_MOUSE E3 ubiquitin-protein ligase RING2...1113.8     35.4     24     41GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0016604; C:nuclear body; IDA:MGI.::GO:0001739; C:sex chromatin; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0009948; P:anterior/posterior axis specification; IMP:MGI.::GO:0001702; P:gastrulation with mouth forming second; IMP:MGI.::GO:0000278; P:mitotic cell cycle; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
197Q7Z7L1    901   SLN11_HUMAN Schlafen family member 11 OS=Homo...724.2     35.8     28     49GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
198Q5R9J5    336   RING2_PONAB E3 ubiquitin-protein ligase RING2...1114.2     35.4     24     41GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0016567; P:protein ubiquitination; ISS:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
199P87176    269   SLX8_SCHPO E3 ubiquitin-protein ligase comple...1674.6     35     26     41GO:0033768; C:SUMO-targeted ubiquitin ligase complex; IPI:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006310; P:DNA recombination; IGI:PomBase.::GO:0033234; P:negative regulation of protein sumoylation; IMP:PomBase.
200Q6PAF4    270   NSE1_XENLA Non-structural maintenance of chro...1904.7     35     21     37GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.
201Q68D06    897   SLN13_HUMAN Schlafen family member 13 OS=Homo...724.9     35.4     28     49GO:0005622; C:intracellular; IDA:LIFEdb.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
202Q8LE94    231   RING3_ARATH E3 ubiquitin-protein ligase At3g0...557.1     34.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
203Q4KLY4    308   RING2_RAT E3 ubiquitin-protein ligase RING2 O...1118.8     34.3     24     41GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0016567; P:protein ubiquitination; ISS:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
records
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