rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | O18404 | 255 | HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty... | 198 | 0.000000006 | 58.9 | 30 | 44 | GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase. | | | | | | | | | | GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 422 | Q50L96 | 256 | ADH_DROAN Alcohol dehydrogenase OS=Drosophila... | 205 | 0.000000007 | 58.5 | 28 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; ISS:UniProtKB. | 423 | P81764 | 278 | ADHR_DROPS Alcohol dehydrogenase-related 31 k... | 136 | 0.000000008 | 58.5 | 32 | 49 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 424 | Q9URX0 | 258 | YLX6_SCHPO Uncharacterized oxidoreductase C92... | 247 | 0.000000009 | 58.2 | 26 | 45 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009060; P:aerobic respiration; IC:PomBase.::GO:0009107; P:lipoate biosynthetic process; ISS:PomBase.] | 425 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 211 | 0.000000009 | 58.5 | 27 | 45 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 426 | O75828 | 277 | CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho... | 184 | 0.000000009 | 58.5 | 28 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | | 427 | Q05528 | 253 | KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de... | 213 | 0.00000001 | 58.2 | 27 | 45 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 428 | P50200 | 267 | HDHA_CLOSO NADP-dependent 7-alpha-hydroxyster... | 250 | 0.00000001 | 58.2 | 22 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 429 | Q5R7K0 | 330 | HSDL1_PONAB Inactive hydroxysteroid dehydroge... | 195 | 0.00000001 | 58.5 | 29 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 430 | Q4X117 | 345 | MKAR_ASPFU 3-ketoacyl-CoA reductase OS=A1100)... | 201 | 0.00000001 | 58.5 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 431 | B0XSI3 | 345 | MKAR_ASPFC 3-ketoacyl-CoA reductase OS=(Asper... | 201 | 0.00000001 | 58.5 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 432 | Q6PUF3 | 287 | DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen... | 242 | 0.00000001 | 58.2 | 24 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN. | | | | | | | | | | | 433 | Q5ZJG8 | 331 | HSDL1_CHICK Hydroxysteroid dehydrogenase-like... | 192 | 0.00000001 | 58.5 | 28 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 434 | A1DH66 | 345 | MKAR_NEOFI 3-ketoacyl-CoA reductase OS=181) (... | 198 | 0.00000001 | 58.5 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 435 | Q17QK8 | 267 | SPRE_BOVIN Sepiapterin reductase OS=Bos tauru... | 205 | 0.00000001 | 58.2 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro. | 436 | Q24640 | 279 | ADHR_DROSU Alcohol dehydrogenase-related 31 k... | 136 | 0.00000001 | 58.2 | 31 | 49 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 437 | P0CR34 | 361 | MKAR_CRYNJ 3-ketoacyl-CoA reductase OS=ATCC M... | 213 | 0.00000001 | 58.2 | 26 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 438 | P0CR35 | 361 | MKAR_CRYNB 3-ketoacyl-CoA reductase OS=(Filob... | 213 | 0.00000001 | 58.2 | 26 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 439 | P71824 | 248 | Y769_MYCTU Uncharacterized oxidoreductase Rv0... | 218 | 0.00000001 | 57.4 | 28 | 45 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 440 | P26620 | 272 | ADHR_DROMA Alcohol dehydrogenase-related 31 k... | 137 | 0.00000002 | 57.8 | 31 | 48 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 441 | Q59V93 | 349 | MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid... | 210 | 0.00000002 | 58.2 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 442 | Q62904 | 334 | DHB7_RAT 3-keto-steroid reductase OS=Rattus n... | 92 | 0.00000002 | 58.2 | 36 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005148; F:prolactin receptor binding; IMP:RGD. | | | | | | | | | | | 443 | Q09007 | 279 | ADHR_DROGU Alcohol dehydrogenase-related 31 k... | 136 | 0.00000002 | 57.8 | 31 | 49 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 444 | P28485 | 202 | ADHR_DROER Alcohol dehydrogenase-related 31 k... | 137 | 0.00000002 | 56.6 | 31 | 48 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 445 | O05919 | 263 | Y927C_MYCTU Uncharacterized oxidoreductase Rv... | 249 | 0.00000002 | 57.4 | 27 | 44 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 446 | Q9MYP6 | 270 | DHB14_BOVIN 17-beta-hydroxysteroid dehydrogen... | 156 | 0.00000002 | 57.4 | 24 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 447 | P56937 | 341 | DHB7_HUMAN 3-keto-steroid reductase OS=Homo s... | 177 | 0.00000002 | 57.8 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 448 | A5DND6 | 341 | MKAR_PICGU 3-ketoacyl-CoA reductase OS=1539 /... | 210 | 0.00000002 | 57.8 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 449 | Q988B7 | 248 | PLDH_RHILO Pyridoxal 4-dehydrogenase OS=Rhizo... | 202 | 0.00000002 | 57 | 29 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050235; F:pyridoxal 4-dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0042820; P:vitamin B6 catabolic process; IDA:UniProtKB. | 450 | Q8K354 | 277 | CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu... | 171 | 0.00000002 | 57.4 | 29 | 45 | | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 451 | P50168 | 427 | DHI2_SHEEP Corticosteroid 11-beta-dehydrogena... | 196 | 0.00000002 | 57.8 | 25 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |