Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR226C
Length:
267
Number of sequences:
5887
Description:
YMR226C YMR226C SGDID:S000004839, Chr XIII from 722396-721593, Genome Release 64-1-1, reverse complement, Verified ORF, "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421O18404    255   HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty...1980.000000006     58.9     30     44GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase.
GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
422Q50L96    256   ADH_DROAN Alcohol dehydrogenase OS=Drosophila...2050.000000007     58.5     28     43
GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0046164; P:alcohol catabolic process; ISS:UniProtKB.
423P81764    278   ADHR_DROPS Alcohol dehydrogenase-related 31 k...1360.000000008     58.5     32     49
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
424Q9URX0    258   YLX6_SCHPO Uncharacterized oxidoreductase C92...2470.000000009     58.2     26     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009060; P:aerobic respiration; IC:PomBase.::GO:0009107; P:lipoate biosynthetic process; ISS:PomBase.]
425O70351    261   HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type...2110.000000009     58.5     27     45
GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD.
GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
426O75828    277   CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho...1840.000000009     58.5     28     47GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.
427Q05528    253   KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de...2130.00000001     58.2     27     45
GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
428P50200    267   HDHA_CLOSO NADP-dependent 7-alpha-hydroxyster...2500.00000001     58.2     22     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
429Q5R7K0    330   HSDL1_PONAB Inactive hydroxysteroid dehydroge...1950.00000001     58.5     29     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
430Q4X117    345   MKAR_ASPFU 3-ketoacyl-CoA reductase OS=A1100)...2010.00000001     58.5     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
431B0XSI3    345   MKAR_ASPFC 3-ketoacyl-CoA reductase OS=(Asper...2010.00000001     58.5     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
432Q6PUF3    287   DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen...2420.00000001     58.2     24     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN.
433Q5ZJG8    331   HSDL1_CHICK Hydroxysteroid dehydrogenase-like...1920.00000001     58.5     28     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
434A1DH66    345   MKAR_NEOFI 3-ketoacyl-CoA reductase OS=181) (...1980.00000001     58.5     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
435Q17QK8    267   SPRE_BOVIN Sepiapterin reductase OS=Bos tauru...2050.00000001     58.2     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB.
GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
436Q24640    279   ADHR_DROSU Alcohol dehydrogenase-related 31 k...1360.00000001     58.2     31     49
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
437P0CR34    361   MKAR_CRYNJ 3-ketoacyl-CoA reductase OS=ATCC M...2130.00000001     58.2     26     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
438P0CR35    361   MKAR_CRYNB 3-ketoacyl-CoA reductase OS=(Filob...2130.00000001     58.2     26     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
439P71824    248   Y769_MYCTU Uncharacterized oxidoreductase Rv0...2180.00000001     57.4     28     45GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
440P26620    272   ADHR_DROMA Alcohol dehydrogenase-related 31 k...1370.00000002     57.8     31     48
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
441Q59V93    349   MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid...2100.00000002     58.2     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
442Q62904    334   DHB7_RAT 3-keto-steroid reductase OS=Rattus n...920.00000002     58.2     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005148; F:prolactin receptor binding; IMP:RGD.
443Q09007    279   ADHR_DROGU Alcohol dehydrogenase-related 31 k...1360.00000002     57.8     31     49
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
444P28485    202   ADHR_DROER Alcohol dehydrogenase-related 31 k...1370.00000002     56.6     31     48
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
445O05919    263   Y927C_MYCTU Uncharacterized oxidoreductase Rv...2490.00000002     57.4     27     44GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
446Q9MYP6    270   DHB14_BOVIN 17-beta-hydroxysteroid dehydrogen...1560.00000002     57.4     24     47
GO:0000166; F:nucleotide binding; IEA:InterPro.
447P56937    341   DHB7_HUMAN 3-keto-steroid reductase OS=Homo s...1770.00000002     57.8     27     47GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
448A5DND6    341   MKAR_PICGU 3-ketoacyl-CoA reductase OS=1539 /...2100.00000002     57.8     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
449Q988B7    248   PLDH_RHILO Pyridoxal 4-dehydrogenase OS=Rhizo...2020.00000002     57     29     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050235; F:pyridoxal 4-dehydrogenase activity; IDA:UniProtKB.
GO:0042820; P:vitamin B6 catabolic process; IDA:UniProtKB.
450Q8K354    277   CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu...1710.00000002     57.4     29     45
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.
451P50168    427   DHI2_SHEEP Corticosteroid 11-beta-dehydrogena...1960.00000002     57.8     25     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
records
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