Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR226C
Length:
267
Number of sequences:
5887
Description:
YMR226C YMR226C SGDID:S000004839, Chr XIII from 722396-721593, Genome Release 64-1-1, reverse complement, Verified ORF, "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391A1C6J8    345   MKAR_ASPCL 3-ketoacyl-CoA reductase OS=3887 /...1980.0000000005     62.4     28     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
392P40579    254   YIV5_YEAST Uncharacterized oxidoreductase YIR...1940.0000000005     61.6     27     49GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
393Q7Z4W1    244   DCXR_HUMAN L-xylulose reductase OS=Homo sapie...2470.0000000006     61.6     27     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
394Q6GV12    332   KDSR_MOUSE 3-ketodihydrosphingosine reductase...1860.0000000008     62     27     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; IGI:MGI.
395P42317    257   YXJF_BACSU Uncharacterized oxidoreductase yxj...2590.0000000008     61.2     25     46
GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
396P50197    250   LINC_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,...1940.0000000009     61.2     28     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.
397Q0U3N7    341   MKAR_PHANO 3-ketoacyl-CoA reductase OS=(Glume...2000.000000001     61.6     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
398Q06136    332   KDSR_HUMAN 3-ketodihydrosphingosine reductase...1860.000000001     61.2     27     49GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
399P37769    253   KDUD_ECOLI 2-dehydro-3-deoxy-D-gluconate 5-de...2460.000000001     60.5     26     45
GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
400P23102    269   XYLL_PSEPU 1,6-dihydroxycyclohexa-2,4-diene-1...2130.000000001     60.8     27     42
GO:0047116; F:1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
401Q5E9H7    312   DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1...1990.000000002     60.8     28     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
402P10807    254   ADH_DROLE Alcohol dehydrogenase OS=Drosophila...1960.000000002     60.5     29     45
GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006066; P:alcohol metabolic process; IEA:InterPro.
403B0D8R3    338   MKAR_LACBS 3-ketoacyl-CoA reductase OS=deceiv...1970.000000002     60.8     27     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
404Q8RJB2    249   BZRD_BACCE Benzil reductase ((S)-benzoin form...1970.000000002     60.1     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.
405Q2KIJ5    331   KDSR_BOVIN 3-ketodihydrosphingosine reductase...1860.000000002     60.8     27     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
406A5E0R1    350   MKAR_LODEL 3-ketoacyl-CoA reductase OS=NBRC 1...2060.000000002     60.8     31     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
407Q9X6U2    258   BDHA_CUPNH D-beta-hydroxybutyrate dehydrogena...1960.000000002     60.1     29     43
GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
408Q13268    258   DHRS2_HUMAN Dehydrogenase/reductase SDR famil...2370.000000002     60.1     26     48GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.
GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB.
409A6QP05    317   DHR12_BOVIN Dehydrogenase/reductase SDR famil...1430.000000003     60.5     27     54
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
410P50163    260   TRN2_DATST Tropinone reductase 2 OS=Datura st...1990.000000003     59.7     27     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC.
411A2RVM0    322   TIC32_ARATH Short-chain dehydrogenase TIC 32,...1560.000000003     60.1     29     51GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
412P50205    241   PHBB_RHIME Acetoacetyl-CoA reductase OS=melil...1930.000000003     59.3     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW.
413Q4P622    350   MKAR_USTMA 3-ketoacyl-CoA reductase OS=Ustila...1960.000000003     60.1     26     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
414A5PJF6    330   HSDL1_BOVIN Inactive hydroxysteroid dehydroge...1910.000000004     60.1     28     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
415A8N6B4    339   MKAR_COPC7 3-ketoacyl-CoA reductase OS=9003) ...1750.000000004     60.1     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
416A0PJE2    317   DHR12_HUMAN Dehydrogenase/reductase SDR famil...1470.000000004     59.7     27     53
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
417O16091    278   ADHR_DROPE Alcohol dehydrogenase-related 31 k...1360.000000005     59.3     32     49
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
418Q12634    283   T4HR_MAGO7 Tetrahydroxynaphthalene reductase ...2560.000000005     59.3     24     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047039; F:tetrahydroxynaphthalene reductase activity; IEA:EC.
GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
419Q22230    309   YVX3_CAEEL Uncharacterized oxidoreductase T05...2540.000000006     59.3     26     44
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
420Q3SXM5    330   HSDL1_HUMAN Inactive hydroxysteroid dehydroge...1950.000000006     59.3     29     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
421O18404    255   HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty...1980.000000006     58.9     30     44GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase.
GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
records
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