Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR226C
Length:
267
Number of sequences:
5887
Description:
YMR226C YMR226C SGDID:S000004839, Chr XIII from 722396-721593, Genome Release 64-1-1, reverse complement, Verified ORF, "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P48814    257   ADH1_CERCA Alcohol dehydrogenase 1 OS=Ceratit...1981e-16     80.1     30     47
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
122O88451    316   RDH7_MOUSE Retinol dehydrogenase 7 OS=Mus mus...2051e-16     80.9     30     50GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.
123O32291    356   YXNA_BACSU Uncharacterized oxidoreductase yxn...2011e-16     81.3     30     51
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
124Q5N800    504   NYC1_ORYSJ Probable chlorophyll(ide) b reduct...2112e-16     82     28     51GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0034256; F:chlorophyll(ide) b reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0015996; P:chlorophyll catabolic process; IMP:Gramene.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; IMP:Gramene.
125P70684    265   PGDH_CAVPO 15-hydroxyprostaglandin dehydrogen...1952e-16     79.7     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
126P55336    244   FABG_VIBHA 3-oxoacyl-[acyl-carrier-protein] r...1963e-16     79.3     30     50
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
127Q8N3Y7    309   RDHE2_HUMAN Epidermal retinol dehydrogenase 2...2013e-16     80.1     31     49GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
GO:0050908; P:detection of light stimulus involved in visual perception; NAS:UniProtKB.::GO:0043616; P:keratinocyte proliferation; IMP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
128Q99LB2    279   DHRS4_MOUSE Dehydrogenase/reductase SDR famil...2515e-16     79     27     49GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
129P15428    266   PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen...1956e-16     78.6     30     48GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
130O54753    317   H17B6_RAT 17-beta-hydroxysteroid dehydrogenas...2057e-16     79     30     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; TAS:RGD.
GO:0008209; P:androgen metabolic process; TAS:RGD.
131Q9BY49    303   PECR_HUMAN Peroxisomal trans-2-enoyl-CoA redu...2157e-16     78.6     27     49GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0033306; P:phytol metabolic process; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
132Q8MJY8    266   PGDH_MACFA 15-hydroxyprostaglandin dehydrogen...1957e-16     78.2     30     48GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
133P73574    247   FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] ...2248e-16     77.8     30     48
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
134O31680    248   YKVO_BACSU Uncharacterized oxidoreductase ykv...1959e-16     77.8     34     51
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
135P50162    273   TRN1_DATST Tropinone reductase 1 OS=Datura st...2219e-16     78.2     28     48
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050356; F:tropine dehydrogenase activity; IEA:EC.
136Q59787    256   DHSO_RHOSH Sorbitol dehydrogenase OS=Rhodobac...1969e-16     77.8     34     47
GO:0003939; F:L-iditol 2-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
137P06234    245   NODG_RHIME Nodulation protein G OS=meliloti)....1979e-16     77.8     29     50
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009877; P:nodulation; IEA:UniProtKB-KW.]
138O16925    314   STDH4_CAEEL Putative steroid dehydrogenase 4 ...1940.000000000000001     78.2     35     50
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
139Q8VCC1    269   PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen...1950.000000000000002     77.4     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
140A2QCH3    346   MKAR_ASPNC 3-ketoacyl-CoA reductase OS=Asperg...1990.000000000000002     77.8     29     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
141Q70UP5    258   ADH2_CERCO Alcohol dehydrogenase 2 OS=Ceratit...1990.000000000000002     76.6     31     47
GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
142O54939    306   DHB3_RAT Testosterone 17-beta-dehydrogenase 3...1920.000000000000002     77.4     33     54GO:0005792; C:microsome; IDA:RGD.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD.
143Q3T0C2    266   PGDH_BOVIN 15-hydroxyprostaglandin dehydrogen...1950.000000000000003     76.6     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0060206; P:estrous cycle phase; IEP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
144Q9BTZ2    278   DHRS4_HUMAN Dehydrogenase/reductase SDR famil...2570.000000000000003     76.6     28     48GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB.
GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.
GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.]
145P37058    310   DHB3_HUMAN Testosterone 17-beta-dehydrogenase...2040.000000000000003     77     32     52GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030539; P:male genitalia development; TAS:ProtInc.
146Q8LEU3    348   NOL_ARATH Chlorophyll(ide) b reductase NOL, c...1970.000000000000003     77.4     29     53GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0034256; F:chlorophyll(ide) b reductase activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0015996; P:chlorophyll catabolic process; IDA:TAIR.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; TAS:TAIR.
147P29147    343   BDH_RAT D-beta-hydroxybutyrate dehydrogenase,...1970.000000000000004     77.4     29     53GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:RGD.
GO:0060612; P:adipose tissue development; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
148Q8CQD2    257   BUTA_STAES Diacetyl reductase [(S)-acetoin fo...1960.000000000000004     75.9     31     51
GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0045150; P:acetoin catabolic process; IEA:InterPro.
149Q80XN0    343   BDH_MOUSE D-beta-hydroxybutyrate dehydrogenas...1970.000000000000004     77     28     53GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
150Q8KWT4    253   BACC2_BACIU Bacilysin biosynthesis oxidoreduc...2400.000000000000005     75.9     25     47
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
151P39483    261   DHG2_BACME Glucose 1-dehydrogenase 2 OS=Bacil...2650.000000000000005     75.9     25     49
GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.]
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