Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR223W
Length:
471
Number of sequences:
5887
Description:
YMR223W UBP8 SGDID:S000004836, Chr XIII from 716715-718130, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P50102    471   UBP8_YEAST Ubiquitin carboxyl-terminal hydrol...4710     977     100     100GO:0071819; C:DUBm complex; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0032947; F:protein complex scaffold; IDA:SGD.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016578; P:histone deubiquitination; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IMP:SGD.::GO:0034729; P:histone H3-K79 methylation; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
2Q09738    449   UBP8_SCHPO Probable ubiquitin carboxyl-termin...4578e-70     235     33     51GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0035616; P:histone H2B conserved C-terminal lysine deubiquitination; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
3P0C8Z3    514   UBP22_BOVIN Ubiquitin carboxyl-terminal hydro...4622e-60     211     32     46
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
4Q5DU02    525   UBP22_MOUSE Ubiquitin carboxyl-terminal hydro...4623e-60     211     32     47
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:MGI.
5Q9UPT9    525   UBP22_HUMAN Ubiquitin carboxyl-terminal hydro...4626e-60     211     31     47GO:0000124; C:SAGA complex; IDA:UniProtKB.
GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; NAS:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:GOC.::GO:0016574; P:histone ubiquitination; IDA:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
6Q9VVR1    735   NOT_DROME Ubiquitin carboxyl-terminal hydrola...4586e-59     211     31     48GO:0000124; C:SAGA complex; IDA:FlyBase.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0021782; P:glial cell development; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0016578; P:histone deubiquitination; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:FlyBase.
7Q6GNI6    523   UB22A_XENLA Ubiquitin carboxyl-terminal hydro...4791e-58     207     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
8Q6DCJ1    523   UB22B_XENLA Ubiquitin carboxyl-terminal hydro...4797e-58     205     30     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
9A6H8I0    506   UBP22_DANRE Ubiquitin carboxyl-terminal hydro...4615e-57     202     31     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
10Q70EK9    711   UBP51_HUMAN Ubiquitin carboxyl-terminal hydro...4754e-56     203     30     45
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
11A6NNY8    438   UBP27_HUMAN Ubiquitin carboxyl-terminal hydro...3654e-52     187     33     49
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
12Q8CEG8    438   UBP27_MOUSE Ubiquitin carboxyl-terminal hydro...3631e-51     186     33     49
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
13Q9LEW0    557   UBP22_ARATH Ubiquitin carboxyl-terminal hydro...5321e-44     169     27     46
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
14O74442    457   UBP16_SCHPO Probable ubiquitin carboxyl-termi...3632e-43     164     32     49GO:0005730; C:nucleolus; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
15Q7M764    540   U17L2_MOUSE Ubiquitin carboxyl-terminal hydro...3326e-41     158     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031576; P:G2/M transition checkpoint; ISS:UniProtKB.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
16Q6R6M4    530   U17L2_HUMAN Ubiquitin carboxyl-terminal hydro...3674e-40     155     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031576; P:G2/M transition checkpoint; IMP:UniProtKB.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
17Q6QN14    398   U17L6_HUMAN Ubiquitin carboxyl-terminal hydro...3697e-40     153     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
18Q61068    526   UBPW_MOUSE Ubiquitin carboxyl-terminal hydrol...3362e-39     153     32     49
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.
GO:0016579; P:protein deubiquitination; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
19A8MUK1    530   U17L5_HUMAN Ubiquitin carboxyl-terminal hydro...3665e-39     152     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
20Q0WX57    530   UBP17_HUMAN Ubiquitin carboxyl-terminal hydro...3668e-39     152     30     48GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
21Q9FPS2    661   UBP25_ARATH Ubiquitin carboxyl-terminal hydro...3482e-38     151     32     49
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
22O57429    357   UBP2_CHICK Ubiquitin carboxyl-terminal hydrol...3618e-38     146     32     47GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:Roslin.
GO:0016579; P:protein deubiquitination; IDA:Roslin.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
23Q9P275    1121   UBP36_HUMAN Ubiquitin carboxyl-terminal hydro...3371e-37     151     31     51GO:0005730; C:nucleolus; IDA:HPA.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
24B1AQJ2    1098   UBP36_MOUSE Ubiquitin carboxyl-terminal hydro...3312e-37     150     31     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
25B2RQC2    1324   UBP42_MOUSE Ubiquitin carboxyl-terminal hydro...3313e-37     150     31     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
26D3ZU96    1325   UBP42_RAT Ubiquitin carboxyl-terminal hydrola...3313e-37     150     31     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
27P0C7I0    530   U17L8_HUMAN Inactive ubiquitin carboxyl-termi...3663e-37     147     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
28E1B9W9    1333   UBP42_BOVIN Ubiquitin carboxyl-terminal hydro...3314e-37     150     31     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
29A6NCW0    530   U17L3_HUMAN Ubiquitin carboxyl-terminal hydro...3664e-37     146     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
30B3M3M6    1091   UBP36_DROAN Ubiquitin carboxyl-terminal hydro...3344e-37     150     31     48GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
31Q9H9J4    1324   UBP42_HUMAN Ubiquitin carboxyl-terminal hydro...3314e-37     150     31     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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