UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YMR223W

Length:

471

Number of sequences:

5887

Description:

YMR223W UBP8 SGDID:S000004836, Chr XIII from 716715-718130, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q9H9J4	1324	UBP42_HUMAN Ubiquitin carboxyl-terminal hydro...	331	4e-37	150	31	51
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
32	A6NCW7	530	U17L4_HUMAN Inactive ubiquitin carboxyl-termi...	366	6e-36	143	29	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
33	A5D9H7	369	UBP12_BOVIN Ubiquitin carboxyl-terminal hydro...	356	7e-36	140	30	47
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
34	Q9Y6I4	520	UBP3_HUMAN Ubiquitin carboxyl-terminal hydrol...	375	3e-35	140	34	46	GO:0000790; C:nuclear chromatin; IDA:UniProtKB.
									GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IMP:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
35	Q9FPS4	859	UBP23_ARATH Ubiquitin carboxyl-terminal hydro...	332	4e-35	143	32	48
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
36	Q91W36	520	UBP3_MOUSE Ubiquitin carboxyl-terminal hydrol...	377	5e-35	140	33	46
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
37	Q7ZUM8	695	UBP44_DANRE Ubiquitin carboxyl-terminal hydro...	91	0.07	39.3	25	44	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021551; P:central nervous system morphogenesis; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
38	Q7RTZ2	530	U17L1_HUMAN Putative ubiquitin carboxyl-termi...	368	5e-35	140	29	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
39	Q9D9M2	370	UBP12_MOUSE Ubiquitin carboxyl-terminal hydro...	357	7e-35	138	29	46
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
40	B4LG38	1214	UBP36_DROVI Ubiquitin carboxyl-terminal hydro...	336	7e-35	143	28	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
41	B3NC86	1085	UBP36_DROER Ubiquitin carboxyl-terminal hydro...	335	2e-34	141	29	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
42	Q9SB51	1008	UBP16_ARATH Ubiquitin carboxyl-terminal hydro...	334	5e-34	140	30	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0008283; P:cell proliferation; IGI:TAIR.::GO:0009908; P:flower development; IGI:TAIR.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0048364; P:root development; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
43	B4IXE0	1240	UBP36_DROGR Ubiquitin carboxyl-terminal hydro...	337	6e-34	140	28	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
44	B4KXJ5	1185	UBP36_DROMO Ubiquitin carboxyl-terminal hydro...	336	6e-34	140	28	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
45	A4FUN7	371	UBP12_DANRE Ubiquitin carboxyl-terminal hydro...	360	7e-34	135	31	46
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
46	B4PIW8	1082	UBP36_DROYA Ubiquitin carboxyl-terminal hydro...	335	7e-34	140	29	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
47	Q2LZB1	1059	UBP36_DROPS Ubiquitin carboxyl-terminal hydro...	334	9e-34	139	29	48	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
48	O75317	370	UBP12_HUMAN Ubiquitin carboxyl-terminal hydro...	357	1e-33	134	29	46
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
49	B4QIS3	988	UBP36_DROSI Ubiquitin carboxyl-terminal hydro...	335	1e-33	139	28	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
50	O75604	605	UBP2_HUMAN Ubiquitin carboxyl-terminal hydrol...	357	2e-33	136	31	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
51	C0HB46	372	UBP12_SALSA Ubiquitin carboxyl-terminal hydro...	361	2e-33	134	30	45
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
52	Q52KZ6	370	UB12A_XENLA Ubiquitin carboxyl-terminal hydro...	357	2e-33	134	29	46
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
53	Q5M981	370	UB12B_XENLA Ubiquitin carboxyl-terminal hydro...	357	2e-33	134	29	46
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
54	Q9FKP5	731	UBP17_ARATH Ubiquitin carboxyl-terminal hydro...	334	7e-33	135	30	47
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
55	O88623	613	UBP2_MOUSE Ubiquitin carboxyl-terminal hydrol...	358	1e-32	134	30	47	GO:0005938; C:cell cortex; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
56	Q5U349	618	UBP2_RAT Ubiquitin carboxyl-terminal hydrolas...	358	1e-32	134	29	47	GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
57	B4MLR8	1311	UBP36_DROWI Ubiquitin carboxyl-terminal hydro...	346	1e-32	136	28	47	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
58	Q9VRP5	1085	UBP36_DROME Ubiquitin carboxyl-terminal hydro...	335	4e-32	134	28	47	GO:0005730; C:nucleolus; IDA:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; IMP:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:FlyBase.::GO:0045824; P:negative regulation of innate immune response; IMP:FlyBase.::GO:0042981; P:regulation of apoptotic process; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
59	D2HBJ8	711	UBP44_AILME Ubiquitin carboxyl-terminal hydro...	91	0.028	40.8	26	44	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
60	Q9H0E7	712	UBP44_HUMAN Ubiquitin carboxyl-terminal hydro...	66	0.15	38.5	27	47	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; IMP:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
61	P40818	1118	UBP8_HUMAN Ubiquitin carboxyl-terminal hydrol...	358	8e-32	133	31	50	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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