Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR223W
Length:
471
Number of sequences:
5887
Description:
YMR223W UBP8 SGDID:S000004836, Chr XIII from 716715-718130, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271A5DAD0    1098   PAN2_PICGU PAB-dependent poly(A)-specific rib...510.015     41.6     47     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
272Q9P2H5    1018   UBP35_HUMAN Ubiquitin carboxyl-terminal hydro...780.8     36.2     31     49
GO:0005488; F:binding; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
273P57080    1055   UBP25_MOUSE Ubiquitin carboxyl-terminal hydro...510.11     38.9     33     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
274P38237    781   UBP14_YEAST Ubiquitin carboxyl-terminal hydro...3830.37     37     20     38GO:0005737; C:cytoplasm; IC:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045721; P:negative regulation of gluconeogenesis; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0016579; P:protein deubiquitination; TAS:SGD.
275Q9UHP3    1055   UBP25_HUMAN Ubiquitin carboxyl-terminal hydro...510.11     38.9     33     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032183; F:SUMO binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.
GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
276O94782    785   UBP1_HUMAN Ubiquitin carboxyl-terminal hydrol...1891.4     35.4     22     41GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0006281; P:DNA repair; TAS:Reactome.::GO:0035520; P:monoubiquitinated protein deubiquitination; IMP:UniProtKB.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
277Q1E873    1222   PAN2_COCIM PAB-dependent poly(A)-specific rib...2420.059     39.7     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
278Q29RP1    783   UBP1_BOVIN Ubiquitin carboxyl-terminal hydrol...1892.3     34.7     22     40GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006282; P:regulation of DNA repair; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
279Q5APK0    1190   PAN2_CANAL PAB-dependent poly(A)-specific rib...1330.071     39.7     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
280A1CEK7    1161   PAN2_ASPCL PAB-dependent poly(A)-specific rib...2450.084     39.3     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
281O42726    1220   UBP2_KLULA Ubiquitin carboxyl-terminal hydrol...500.086     39.3     36     50
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
282Q01476    1272   UBP2_YEAST Ubiquitin carboxyl-terminal hydrol...480.11     38.9     35     52GO:0005737; C:cytoplasm; IC:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
283Q0UPL5    1129   PAN2_PHANO PAB-dependent poly(A)-specific rib...1560.15     38.5     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
284Q8C2S0    505   UBP44_MOUSE Inactive ubiquitin carboxyl-termi...820.32     37.4     28     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
285Q09931    1307   UBPY_CAEEL Probable ubiquitin carboxyl-termin...1140.45     37     28     40
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
286Q569C3    784   UBP1_RAT Ubiquitin carboxyl-terminal hydrolas...2081     35.8     22     41GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006282; P:regulation of DNA repair; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
287A2QW83    1150   PAN2_ASPNC PAB-dependent poly(A)-specific rib...1420.59     36.6     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
288Q9P3U0    1141   UBP2_SCHPO Probable ubiquitin carboxyl-termin...1900.76     36.2     24     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
289Q6FS70    1093   PAN2_CANGA PAB-dependent poly(A)-specific rib...1370.79     36.2     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
290Q8BJQ2    784   UBP1_MOUSE Ubiquitin carboxyl-terminal hydrol...1500.92     35.8     26     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006282; P:regulation of DNA repair; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
291Q9UBN7    1215   HDAC6_HUMAN Histone deacetylase 6 OS=Homo sap...921.1     35.4     26     47GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0031252; C:cell leading edge; IDA:BHF-UCL.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; IDA:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0070840; F:dynein complex binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:BHF-UCL.::GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:BHF-UCL.::GO:0070846; P:Hsp90 deacetylation; IMP:BHF-UCL.::GO:0032418; P:lysosome localization; IMP:BHF-UCL.::GO:0016236; P:macroautophagy; IMP:BHF-UCL.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:BHF-UCL.::GO:0010727; P:negative regulation of hydrogen peroxide metabolic process; IC:BHF-UCL.::GO:0051354; P:negative regulation of oxidoreductase activity; IC:BHF-UCL.::GO:0045861; P:negative regulation of proteolysis; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0034983; P:peptidyl-lysine deacetylation; IMP:BHF-UCL.::GO:0070845; P:polyubiquitinated misfolded protein transport; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0090035; P:positive regulation of chaperone-mediated protein complex assembly; IMP:BHF-UCL.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0009967; P:positive regulation of signal transduction; IMP:BHF-UCL.::GO:0060765; P:regulation of androgen receptor signaling pathway; TAS:BHF-UCL.::GO:0060632; P:regulation of microtubule-based movement; IC:BHF-UCL.::GO:0010469; P:regulation of receptor activity; IMP:BHF-UCL.::GO:0070848; P:response to growth factor stimulus; IMP:BHF-UCL.::GO:0009636; P:response to toxin; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0090042; P:tubulin deacetylation; ISS:UniProtKB.
292P43093    417   CARP4_CANAW Candidapepsin-4 OS=Candida albica...582     34.7     40     55GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
293Q2ULU6    1155   PAN2_ASPOR PAB-dependent poly(A)-specific rib...2412.2     34.7     20     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
294Q7CRB7    288   ACCD_STRR6 Acetyl-coenzyme A carboxylase carb...702.4     33.9     30     50GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
295P0CC08    288   ACCD_STRPN Acetyl-coenzyme A carboxylase carb...702.4     33.9     30     50GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
296P53095    428   DSD1_YEAST D-serine dehydratase OS=Saccharomy...613.5     33.9     36     51
GO:0008721; F:D-serine ammonia-lyase activity; IDA:SGD.
GO:0070178; P:D-serine metabolic process; IMP:SGD.
297Q54QE6    512   SIR2A_DICDI NAD-dependent deacetylase sir2A O...756.7     32.7     24     44
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
records
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