Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR217W
Length:
525
Number of sequences:
5887
Description:
YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931P07259    2214   PYR1_YEAST Protein URA2 OS=Saccharomyces cere...1780.25     38.1     23     42GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:SGD.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0045984; P:negative regulation of pyrimidine base metabolic process; IDA:SGD.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
932Q44696    200   TRPG_BUCAI Anthranilate synthase component 2 ...1100.25     37     25     45
GO:0004049; F:anthranilate synthase activity; IEA:EC.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
933Q2RGW0    210   HIS5_MOOTA Imidazole glycerol phosphate synth...1400.3     36.6     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
934Q4JCP0    279   NADE_SULAC NH(3)-dependent NAD(+) synthetase ...330.3     37     48     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
935P59118    210   HIS5_LEPIN Imidazole glycerol phosphate synth...2280.31     36.6     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
936P61780    210   HIS5_LEPIC Imidazole glycerol phosphate synth...2280.31     36.6     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
937Q2JN09    218   HIS5_SYNJB Imidazole glycerol phosphate synth...1280.33     36.6     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
938Q3A450    376   CARA_PELCD Carbamoyl-phosphate synthase small...1950.36     37     26     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
939Q87EB9    374   CARA_XYLFT Carbamoyl-phosphate synthase small...970.37     37     32     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
940A4SFG4    277   NADE_PROVI NH(3)-dependent NAD(+) synthetase ...1910.37     36.6     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
941A0Q152    350   MNMA_CLONN tRNA-specific 2-thiouridylase MnmA...760.42     36.6     34     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
942Q49WY3    366   CARA_STAS1 Carbamoyl-phosphate synthase small...2110.43     36.6     20     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
943Q8RG87    358   CARA_FUSNN Carbamoyl-phosphate synthase small...1770.48     36.6     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
944Q2YAU8    212   HIS5_NITMU Imidazole glycerol phosphate synth...1370.49     36.2     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
945Q9X7C0    206   HIS5_MYCLE Imidazole glycerol phosphate synth...1330.52     35.8     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
946Q91TW9    2027   POLG_MRFVC Genome polyprotein OS=Maize rayado...710.55     37     34     52GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:InterPro.::GO:0008174; F:mRNA methyltransferase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.
947A4SXM1    397   CARA_POLSQ Carbamoyl-phosphate synthase small...2020.55     36.6     25     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
948C6A5B5    254   NADE_THESM NH(3)-dependent NAD(+) synthetase ...660.56     36.2     29     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
949Q2RNA5    214   HIS5_RHORT Imidazole glycerol phosphate synth...1290.61     35.8     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
950Q8KF56    201   HIS5_CHLTE Imidazole glycerol phosphate synth...2050.68     35.4     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
951O27568    198   HIS5_METTH Imidazole glycerol phosphate synth...1250.73     35.4     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
952Q4J8E9    371   CARA_SULAC Carbamoyl-phosphate synthase small...1660.74     36.2     27     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
953Q12V31    263   NADE_METBU NH(3)-dependent NAD(+) synthetase ...330.75     35.8     39     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
954A8M7X6    154   NRDR_SALAI Transcriptional repressor NrdR OS=...950.82     34.7     34     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
955C4XRH8    375   CARA_DESMR Carbamoyl-phosphate synthase small...1780.89     35.8     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
956Q8ZU97    397   ASSY_PYRAE Argininosuccinate synthase OS=/ NB...680.94     35.8     26     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004055; F:argininosuccinate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.
957O28995    358   CARA_ARCFU Carbamoyl-phosphate synthase small...1780.94     35.8     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
958P61782    203   HIS51_METMP Imidazole glycerol phosphate synt...1311.1     35     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
959Q7VBF5    213   HIS5_PROMA Imidazole glycerol phosphate synth...1301.2     34.7     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
960A4X4W8    154   NRDR_SALTO Transcriptional repressor NrdR OS=...951.3     34.3     33     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
961B5Y8Q4    296   NADE_COPPD NH(3)-dependent NAD(+) synthetase ...391.4     35     44     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
records
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