Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR217W
Length:
525
Number of sequences:
5887
Description:
YMR217W GUA1 SGDID:S000004830, Chr XIII from 701790-703367, Genome Release 64-1-1, Verified ORF, "GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901P71811    376   CARA_MYCTU Carbamoyl-phosphate synthase small...1810.067     39.3     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
902Q65RB8    194   HIS5_MANSM Imidazole glycerol phosphate synth...1290.068     38.5     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
903Q9CCR3    375   CARA_MYCLE Carbamoyl-phosphate synthase small...1980.068     39.3     22     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
904Q6F0U4    244   NADE_MESFL NH(3)-dependent NAD(+) synthetase ...2050.08     38.5     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
905P05328    770   TRPG_ASPNG Anthranilate synthase component 2 ...1590.08     39.3     23     38
GO:0004049; F:anthranilate synthase activity; IEA:EC.::GO:0004425; F:indole-3-glycerol-phosphate synthase activity; IEA:EC.::GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
906Q66ER8    391   CARA_YERPS Carbamoyl-phosphate synthase small...2100.081     39.3     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
907Q8ZIL5    391   CARA_YERPE Carbamoyl-phosphate synthase small...2100.081     39.3     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
908Q0U5H7    476   CARA_PHANO Carbamoyl-phosphate synthase argin...1870.091     38.9     21     33GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.
909Q9HNM7    268   NADE_HALSA NH(3)-dependent NAD(+) synthetase ...2020.11     38.5     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
910B0R6W9    268   NADE_HALS3 NH(3)-dependent NAD(+) synthetase ...2020.11     38.5     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
911P38098    378   CARA_PSEAE Carbamoyl-phosphate synthase small...970.11     38.5     30     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
912Q88DU5    378   CARA_PSEPK Carbamoyl-phosphate synthase small...910.12     38.5     31     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
913Q9PEC2    374   CARA_XYLFA Carbamoyl-phosphate synthase small...970.12     38.5     32     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
914Q8A7Z4    196   HIS5_BACTN Imidazole glycerol phosphate synth...1400.13     37.7     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
915Q752N9    399   CARA_ASHGO Carbamoyl-phosphate synthase argin...1260.13     38.5     29     34GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.
916P58893    393   CARA_CORGL Carbamoyl-phosphate synthase small...1990.13     38.5     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
917P58896    375   CARA_XANCP Carbamoyl-phosphate synthase small...1990.13     38.5     25     37
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
918P58895    391   CARA_XANAC Carbamoyl-phosphate synthase small...2020.13     38.5     24     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
919Q7MAJ5    257   NADE_WOLSU NH(3)-dependent NAD(+) synthetase ...320.13     38.1     50     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
920Q741H2    373   CARA_MYCPA Carbamoyl-phosphate synthase small...1770.13     38.5     23     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
921Q3A3F8    352   MNMA_PELCD tRNA-specific 2-thiouridylase MnmA...2010.15     38.1     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
922P36838    353   CARX_BACSU Carbamoyl-phosphate synthase argin...1860.15     38.1     26     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.
923Q9ZJY9    375   CARA_HELPJ Carbamoyl-phosphate synthase small...1800.15     38.1     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
924P62448    210   HIS5_PHOPR Imidazole glycerol phosphate synth...1340.17     37.4     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
925Q8FT41    400   CARA_COREF Carbamoyl-phosphate synthase small...1770.17     38.1     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
926Q97KI0    203   HIS5_CLOAB Imidazole glycerol phosphate synth...1320.19     37.4     32     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
927Q8PVD5    202   HIS5_METMA Imidazole glycerol phosphate synth...1390.19     37.4     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
928Q5SLL3    391   CARA_THET8 Carbamoyl-phosphate synthase small...1750.21     37.7     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
929Q72GZ0    391   CARA_THET2 Carbamoyl-phosphate synthase small...1750.21     37.7     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
930Q91437    2242   PYR1_SQUAC CAD protein OS=Squalus acanthias (...980.24     38.1     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
931P07259    2214   PYR1_YEAST Protein URA2 OS=Saccharomyces cere...1780.25     38.1     23     42GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:SGD.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0045984; P:negative regulation of pyrimidine base metabolic process; IDA:SGD.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
records
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